Fibromyalgia Action UK
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CRP level

My CRP count has come back at 15 my consultant doesn’t seem overly worried but it’s sent me into panic mode anyone else have a high CRP count. Thanks xx

75 Replies
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Hi Shazanabs,

Don't panic, I had a high CRP level before. It means there is inflammation some where in the body but unfortunately it can't be pinpointed to a particular part of the body.

That was a few years ago and my GP didn't seem overly concerned about it either.

Take care,

Mags 🌼💐🌼

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CRP should be less than 5. The lower, the better. Chronic inflammation causes &/or worsens Cardiovascular Disease.

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Really unless it is monitored very regularly and is consistently high it's not something to be overly concerned about and although outside ideal range 15 isn't so bad! It does relate to inflammation 'somewhere' in the body but really just at the time of testing and can be related to any passing infection causing inflammation.it goes both up and down quickly when problem arises and then passes. Don't worry too much about it!

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If your consultant doesn't seem overly worried then there is nothing for you to panic about. However if it's causing you stress then I would express your concerns to your consultant so they can re-assure you. x

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Thank you all for your reply’s I do feel a bit better about it, but will speak to my consultant xx

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What is your consultant a specialist of?

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He is a professor in gastroenterology xx

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He should know that if your CRP remains elevated on a longterm basis, it is not a good thing. If he doesn't know this, I'd be concerned as to why he doesn't know it.

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I think he will know and keep an eye on it being a professor he should know what your saying x

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Hi,

I've been seeing a professor on and off for years. At no time did he ever reveal or mention that chronic infection/inflammation causes or worsens cardiovascular disease. So I asked him, at my last appt, if he was aware of this? And he asfmitted that he did. And yet, not once, had he ever shown or expressed any concern for my frequently elevated CRP.

Next month I will be seeing a Heart Surgeon.

Cheers. 🖖🏻

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That doesn’t sound good I’m quite worried now I will be getting in touch with him on Monday X

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From here on, keep a check on your CRP and everything else.

That means getting a printout of your lab results with the reference ranges every single time a new lab test is done for anything.

Was your Vit D level tested? Inadequate levels will also affect inflammation/infection/cancer/etc.

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I’m on vitamin D daily and my levels are now fine, I will definitely be asking for printout of further blood work, does high CPR mean I’m at a higher risk of cancer?x

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What level is your Vit D? And how much Vit D do you take daily?

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I had a booster course of 2000 daily for a month I then had blood test the doctor said it shown normal range but to take 400 daily for the rest of my life x

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What is "normal"?

Did you not get the actual result?

When were you put on the 400 IU daily dose?

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The doctor just said within normal range and I was put on 400 after booster course and blood test x

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Best to get your own copy of the lab results and references ranges... otherwise, you will not know what your exact result was.

400 IU is very likely to be totally adequate.

Assuming you're of average height and weight, I'd say that 2000 IU most probably did not get you to the Optimal range.

I've just seen your other posts - how long have you been experiencing physical pain? And whereabouts was/is the pain?

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I have had physical pain for the last 4 years, the pain is neck shoulders lower back hips wrists elbows knees and feet,been diagnosed with fibro and osteoarthritis I also have a lot of stomach issues x

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The symptoms that you just gave me are frequently associated to Vit D that is low or inadequate. Your Vit D level was not optimal and is (probably) still not optimal.

For further info see my Vit D post. First focus on the very first PDF in my post, signed by 48 scientists who have each researched Vit D for many years and even decades. For example, Prof Michael Holick has researched Vit D for over 40 years and is also an Endocrinologist.

The thyroid, the brain, and just about everything else has less chance of functioning optimally if/when we are deficient in Vit D.

Any competent doctor should know that Low Vit D causes/exacerbates bone pain, joint pain, muscle pain, fatigue, poor stamina, poor quality sleep, depression, inflammation, osteoporosis, cardiovascular disease, cancer... and many other symptoms and conditions.

healthunlocked.com/thyroidu...

🖖🏻

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“I have had physical pain for the last 4 years, the pain is neck shoulders lower back hips wrists elbows knees and feet”

Hi Shazanabs

I too have FIBRO, had it for many years, but got to a stage last year where I had no good days at all, it felt like my body was completely seizing up. Especially, in the areas you stated above.

Five visits to doctors over months & blood tests always done, (unknown to me they were actually LOOKING for a raised CRP & ESR) But my results were always normal.

My own registered GP decided to go with her own thoughts as to what was causing all this pain & weakness, especially in the upper part of the body, but it is typically in every area you described, She started me on a dose of steroids. By next day, I felt every part of my body start to “free” itself. By day two, I could lift my arms had NO frozen shoulder, no real pain at all, This is the indicator for PMR (Polymyalgia Rheumatica)

PMR IS inflammation in the BLOOD VESSELS.. If your doctor is the sort that you can talk to, I would suggest raising PMR with her, as the USUAL way to diagnose PMR is with a blood test (Not everyone has the raised blood markers) & those markers are raised CRP & ESR. And no I do not have a clue what they stand for..

PMR is also considered an older persons disease, this could be why your doctors are not considering it at all, if you are under under 60, but there are many people who do get it younger, it is also a condition many doctors are quite ignorant about.

But if you continue to be in pain with no relief, ASK your doctor to try you on a dose of steroids for a week, (this won’t harm you) if it is PMR, it will feel like a miracle cure, however there is no cure, the steroids only keep the inflammation at bay. But it burns itself out eventually over a period of years...

Take care...

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Thank you I will be asking my doctor about this xx

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No it does not.

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Does not mean risk of cancer do you mean ? X

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Yes. Thing is long term highly raised crp is an indicator of inflammation in the body,somewhere. your reading of 15 although may seem alarming being over the range, is nothing to get panicked about! All test results such as this must be read and acted on from a position of knowledge of the particular patient - not just on the isolated results that are sometimes thrown up from blood tests-and this is what your consultant will be aware of when coming to his conclusions. Crp can rise alarmingly and quickly resolve also i.e. Pneumonia can give it in the 100's, and treatment for an acute illness can see it back under 10 or so very soon, any, even slight inflammatory condition can raise it, and this can be very transient, a flare of say IBS, arthritis, cold or day to day viruses that many times we are unaware of even having,can do this, hence it's so important for it to be read along with knowledge of the patient ,then a sensible conclusion can be arrived at.it is true that a long term raised crp needs to be looked into thoroughly but from what you have said at present you really would do well to put the worry of it aside as your consultant has indicated. since it has been flagged as slightly raised this one time it probably useful to have it checked again in a while to see where it's at but again in conjunction with your gp who knows what background you have. The stress and worry long term is more likely to trigger cancer than a crp 1 off of 15, so try to relax lol. Hope that helps a bit

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Thank you that’s made me feel slightly better x

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Mine is 16 so every 3 months I have a blood test

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Chronic/longterm raised CRP is an issue. Your consultant should be aware of the health implications. Not all consultants know or care.

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It is the first time it’s come back this high

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Mine is always raised when i have blood. and as i see from patient access, doctor writes acceptable

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Hi Matt,

How raised? 🤔

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Hi Londinium

I have not had a normal CRP level or ESR in several years I also have Vit D problems.

I have chronic pancreatitis, lymphedema, raynauds, anemia Hashimotos disease & psoriasis. My endocrinologist appears to be of the opinions I am suffering from dome type of systemic or mixed connective tissue disease but because my antigen tests have come back normal over the last year my rhuemotologist wont officially diagnose Lupus SLE but has said they are 99.9% I have it as I also have a Malar rash & hair loss on top of everything else. I did however have 3 positive (albeit weak) lupus tests 4 yrs ago but it went back to normal. My sister passed away with multiple organ failure from an undiagnosed unknown illness. I am really worried but can't seem to get anywhere yet they have me on so many meds I just want to be treated for one thing. I will read your posts and PDF thanks for the advice you've been giving people it's helping me.

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You're welcome. Would be great if you had the actual result of your Vit D blood test with the reference range. It should all be on the printout that you're entitled to ask for and get, cos it's your data. 🖖🏻

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Thank you again Londinium

I will ask for a print out tomorrow as I also need my TSH print out too. I do know the doctor said (even after 2 yrs on Vit D tablets) it's not where had like it to be but it's improved and I need to stay on them. I'm also concerned though about a vit E test thats just come back from my gastorologist who said they will discuss it with me at this week's appointment. My rhuemotologist said my bloods are all over the place my esr, crp my lymphocytes and platelets and Vits D & E and my TSH levels.

It's a worry. 🤘

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You need a printout of your full thyroid panel of FT3, FT4, TSH, and antibodies etc... plus any other blood tests that were done. For example, any tests that were done to measure inflammation, vitamins, minerals, etc. When you get those results, make sure to post the results WITH the reference ranges on the Thyroid UK forum:

healthunlocked.com/thyroiduk

Remember to give brief detail of what you were/are diagnosed with and what you have been prescribed, etc.

Every time the GP or hospital run some lab tests, make sure to say that you want the printout of the results WITH the reference ranges.

How long in total have you been on Vit D? And what dose have you been prescribed or advised to take throughout all this time? 🤔

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last 5 blood tests=25 then 20 then 32 then 17.5 latest 13.7 I was also put on statins seems to be coming since But i have other health conditions and am under two different consultants

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Matt,

Were you told why you were prescribed statins? Which statin, and what dose?

Any symptoms since starting them? 🤔

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Doctor said because of bad cholesterol strength Atorvastatin 20 mg. No side effects since starting them . Also been put on Irbesartan 75 mg around the same time

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You have high cholesterol and high blood pressure?

Always get the printout of your lab results with the reference ranges - it's your data.

Cholesterol in and of itself isn't terribly useful. It's best to get the breakdown of all the lipids, plus any other lab results that are done.

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About the time my CRP was 32 my GFR for kidneys went down to 35. Since starting Irbesartan my GFR has come up to 48 and CRP down to 13,7 last blood test so must be doing some good then

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Matt,

Hopefully, you'll find my reply above to Shazanabs helpful. 🖖🏻

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Don't worry about CRP as a common cold will rase it.

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Hi Sazanabs

I was hospitalised a few years ago with Diverticulitis my CRP then was 239 it was all a bit dramatic with emergency scans in the middle of the night - Dr's took notice then I had a posse of them around my bed.So I was hooked up to intravenous antibiotics and pain relief. I had to stay in hospital until the CRP levels dropped below 50 which took a week. CRP levels should be under ten I was told.

I think my CRP levels are always raised a bit because of my osteoarthritis and probably Fibro as well. So that could be the reason for your raised level.

So do not worry too much.

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An autoimmune specialist informed me at a social gathering that she likes to see CRP consistently less than 5. She was shocked that my CRP and ESR are consistently elevated but not one had medic cared or showed interest. My Homocysteine is often also high. In three decades my ESR has never been in range but not one medics gave a damn and always brushed it off when I queried it.

I'll soon be seeing a Cardiologist. I think he'll give a damn but it's a shame it had to get to this. I put the above down to medical ignorance, medical incompetence and medical disinterest.

🖖🏻

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Hi Shazanabs, this is my first comment on here although I have been here for some time - My CRP has been as high as 41 and I was booked in for an ablation on my heart and the anaesthetists came to me as I sat all prepped ready for the procedure and said they couldn't risk doing it as it was through the roof, they asked me to go to my GPs and get the reason found, this was 4 years ago now and my rheumatologist who diagnosed me with Fybro and all Drs have just said its high but we cant find why but its ok! - I have had countless bloods done like 11 bottles at a time and they cant find a cause, although the Rheumy did say maybe it was due to me being overweight, until I told her that its been like it for 9 years now and before I gave up smoking 7 years ago I was 6 stone lighter and it was still in its late 30s! If you can get them to find a cause please let me know what they done ! Happy mothers day all the mums x-x

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Amen to that. 🖖🏻

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Please see my reply to vivdk above. 🖖🏻

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I will be sure to let you know if I find out the cause for it xx

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Hi try not to worry. Mine have been up and down currently it has been at 64. And last blood test done it has come down to 33. So my Rhemotogly dr is happier. But my elevate all the time. Even thou I’m on humira. Keep a positive mind I’m sure it will eventually come down. I have inflammatory arthritis and fibromyalgia Hope you feel better soon

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Aww thank you hope your well also xx

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My husbands was 391. Went to hospital was in for 14 days. His crap was 15 then 40 and 2 weeks later 13. So no worries

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Hi for the last 10 yrs my CRP levels have never dropped below 19 at one time it was 104 yes really and that did cause panic its now just normal for me to have a high reading now but as i say to my doctor maybe you understand the permanent pain im in

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I had to go google CRP to know what it was. C-reactive protein which is a liver function test which can be elevated due to infection, (anithesia sent mine through the roof if 5 is normal high end mine was 500!) to cancer. Is this the first time it was elevated? 🤔hmm? Come to think of it I have some stuff which was high on my last lab test that the doctor wasn’t concerned about. How high is your CRP? It may be one of those things that doctors just watch along with other data symptoms, medications side effects etc. If it continues to remain high talk to your doctor in ways to bring it down or if need to do farther testing. Fibromyalgia is an autoimmune disease which means inflammation. Right now mine feels like it is high. Oh puma granite juice is a good source of anti inflammatories. I have been drinking it every morning after breakfast for the last year or two.

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I have had physical pain for the last 4 years, the pain is neck shoulders lower back hips wrists elbows knees and feet,been diagnosed with fibro and osteoarthritis I also have a lot of stomach issues

Your post above sounds like I wrote it, I have all the same problems. I think that you need to leave the worrying to your doctor, if you have no confidence in him ask for a second opinion or change your doctor. There are so many variables in regard to your CRP levels that without the appropriate training you will in all probability be worrying for nothing. I often had very serious lung infections but my CRP levels mostly stayed low but it has been in the 200's and I am still here, of course it was only that high with an active infection present. To sum up I really would place my faith in my doctor and try to stop worrying. Good luck I hope that you feel better soon.

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I hope your Vit D was tested and treated as it can help with pain, etc. 🖖🏻

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I have osteopenia and as such take Calcichew, I have found nothing that can help with my pain other than not moving ! (seriously). I am much too complicated to get things fixed without being hospitalised for a comprehensive review of my medication and treatments. No one is willing to fund such an exercise. So I am putting my faith in the fact that my health care professionals are doing their best and will get on with my life until an alternative treatment plan and medication review can be arranged.

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Thank you for your reply. You didn't say how many calcichew you take daily or whether, and how much, Vit D the calcichew contains. If you have a link to the exact product that would be helpful.

As you have bone density issues, and you have pain and inflammation issues, it's important to keep your Vit D level Optimal.

I guess I'd be wondering what your actual Vit D result was when it was tested, and what dose of Vit D you were then prescribed?

🤔

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Calcichew D3 Forte chewable tablets, see link;

medicines.org.uk/emc/files/...

I have been very ill for a long time, I have over 20 diagnosis' ( I think ) with 35 repeat prescriptions. I have been experiencing a hiatus in my hospitalisations with no inpatient treatment for infections for four years. Mostly now I am in pain and am extremely fatigued.

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Hi Wheezybronch,

Thank you for your reply... but it did saddened me.

If that is the correct link to the product, and you are taking just one of that per day, you can check for yourself that it appears that you're taking a daily dose of just 400 IU. Is that correct? Please confirm.

When was your Vit D tested? Were you given the printout of your lab result with the lab reference range? It is a good idea to get the printout of your lab results and reference ranges.

If your Vit D was tested and found to be low, and you were then after that prescribed just 400 IU per day of Vit D, I think I can safely assume that your Vit D never had a chance of getting into the optimal range on that dose. And that is why your reply saddened me.

So I'm left wondering who tested your Vit D? When did they test it? What was your actual score? And why did they only prescribe 400 IU?

And, was your Vit B12 also tested? If so, what was the actual score?

The following PDF statement was signed by 48 scientists who have each researched Vit D for many years and even decades e.g. Prof Holick has researched Vit D for over 40 yrs and is also an Endocrinologist.

grassrootshealth.net/wp-con...

healthunlocked.com/thyroidu...

🖖🏻

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I am also on Adcal D3 as a maintenance follow up. I was given a high dose of something else first for 6 weeks to bring my Vit D levels up. Then keep on Adcal D3 for maintenance, Also my doctor told me as I have CKD and I am under a Nephrologist he said its ok for me to take them

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What dose of Vit D is in the Adcal? Do you have the link? I'm guessing you take just one per day?

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2 a day Adcal D3 1.5g/400iu

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Matt,

If they're 400 IU each and you take two, you're taking 800 IU total per day i.e. not much.

Here's the PDF statement of 48 scientists regarding Low/Inadequate levels of Vit D causing or exacerbating many symptoms and conditions. Vit D is not just for bones. It is vital for the immune system. It empowers the immune system to fight infections, disease, inflammation, cancer, etc. It is also necessary for the brain. For the avoidance of doubt, it is best that you read the PDF statement yourself and look at the list of scientists, most of whom are PhD professors and MD medics, and draw your own conclusions.

Prof. Holick has researched Vit D for over 40 years and he is also a professional Endocrinologist. He takes a daily Maintenance dose of 3000 IU per day, all year round. He tests his blood levels of Vit D to ensure that he remains in the Optimal range of Vit D, rather than in a Low or Inadequate range.

The Optimal range is stated in BOLD FONT in the PDF statement of the scientists below.

The Maintenance dose is the dose you take AFTER you get into the Optimal range.

In other words, your first goal is to get into the Optimal range. Your second goal is to Maintain the Optimal range. If your Vit D level was/is Low, and you took the Maintenance dose, you will still not be in the Optimal range. And the only way to know, is to get a Vit D blood test before supplementing and then again (afterwards) to see if you find that you're in the Optimal range, you can then lower your daily dose to a Maintenance dose.

Each time you have a lab test for anything, remember to get the hprintout of your lab results WITH the reference ranges (which should be stated alongside each lab result).

Magnesium is one of the Co-Factors of Vit D. So, in some rare instances, a person on a loading dose of Vit D may experience some pain - this is often because they require more Magnesium.

grassrootshealth.net/wp-con...

healthunlocked.com/thyroidu...

Of the many stories that I could give you, I shall provide you with just a fraction of one - mine.

I was ill for many, many years. I suffered many chronic chest infections including pneumonia and pleurisy. I also had chronic pain in my bones, limbs, joints, muscles, wrists, arms, fingers, knuckles, etc. My movement became increasingly limited. My shoulders and hips were in pain and I had less flexibility and mobility. My stamina was poor. My energy was low. I had chronic fatigue. Etc, etc, etc. Eventually, a chest/respiratory professor referred me to a renowned Immunologist. The Immunologist did a load of blood tests. He concluded that all my bloods were fine but he suggested a pneumonia vaccine. I declined. He wrote to my GP saying all my bloods were fine. He wrote to the professor of chest/respiratory saying all my bloods were fine. About 4 years or so later I got a copy of my medical file from the hospital and I insisted that all my hospital lab results and reference ranges be included too. It should have all been provided within 40 days - according to regulations relating to a Subject Access Request. (You can get further info from the ICO about getting a copy of your data). The hospital took almost 1 year, instead of the maximum 40 days. When I eventually looked through it, I found that the renowned Immunologist had done a Vit D test, and the result was Low and he'd drawn a circle around it and, if I remember correctly, had added an exclamation mark. So he knew that my Vit D was low. And yet he never informed me, or my GP, or my chest/respiratory Professor. He just let me continue with chronic bone, joint and muscle pain, and infections, and inflammation, and less mobility, and fatigue, etc, etc, etc. Instead of prescribing/advising Vit D... he prescribed/advised me to have a vaccine. 😟

So I researched Vit D to see if there was any connection between my symptoms/conditions and Low/Inadequate Vit D? I watched scores of online lectures, conferences and interviews by professors, medics, scientists and researchers in this field. And I also viewed scores of published scientific and medical papers on Vit D and associated symptoms/conditions.

I then requested a DEXA Bone Scan from my GP which he declined and (wrongly) advised that there was absolutely no possibility of me having bone density/loss issues until I was at least in my sixties or so. When the GP left the practice, I made the same request from a locum for a DEXA Bone Scan. He agreed, and I was then found to have Osteoporosis.

I had reported bone pain and muscle pain and joint pain and chronic fatigue etc for at least two decades. I had, in effect, reported the common symptoms of Low/Inadequate Vit D... which went unrecognised by every single GP and every single hospital consultant that I'd seen throughout the entire two decades and more.

In addition to the above, it is important to test Vit B12, and a full thyroid panel.

Low Vit D, Low Vit B12 and other low levels of nutrients etc can/will impair health and thyroid function. So it is important to maintain Optimal levels of these things - and I've had that corroborated by a private Professor of Endocrinology.

🖖🏻

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I have low Vit B12 and have Injections every three months. I have no idea about lab results for vit D levels, I was pxd Calcichew to combat low bone density and I take two a day. I am adrenal insufficient and am on Hydrocortisone. Frankly, if I delved into my problems and each and every drug and treatment I would have no time left to live. So I trust my doctors/consultants to do the best they can for me. I will continue to do that until I feel that it is not in my best interests. Although I have often said that knowledge is power it is not that simple, the interpretation of statements and trials or research is very variable and to the layman often quite incomprehensible. The interaction between various drug combinations is endless and unless I get a team of specialists in each and every problem I have I can see no useful information for me. I have just had an horrendous bout of GORD with acid affecting my mouth , nose and even my eyes although already on 20mg omeprazole twice a day it was doubled, I was offered Ranitidine but for the moment settled for doubling my omeprazole as it had been very effective for a long time. The strategy worked and I am now stabilised. I will be looking into that situation as that dose is too high even for me. Most of the evidence against omeprazole is anecdotal and I prefer to gauge my reaction to certain drugs and then discuss it with my doctors. I could investigate, weigh up evidence write summary's etc. but I would rather get on with living. Thank you for your interest and imparting your knowledge. Regards.

PS I am aware of the importance of vit D, this is from answer I posted to someone else;

As to Vitamin D ;"Experts aren't sure exactly why, but they think that you can get muscle and bone pain if you don't get enough of this nutrient. In one study, researchers gave people with fibromyalgia who had low levels of vitamin D a daily supplement or a placebo (a dummy pill) for about 6 months. Those who took the supplement had less pain and fatigue

Thanks again !

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I agree with Londinium as Rheumatologist wrote to my GP telling them to stop my Adcal D3.Then for 8 weeks give me a high dose replacement therapy and after that and more blood tests put me back on Adcal D3 as a maintenance 2 a day. Without the high dose therapy for 8 weeks it will never come up to required level

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Thank you for your input.

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Hi Matt,

You should get the printout to see what your Vit D result was BEFORE and AFTER those 8 wks. Out of interest, what dose of Vit D did they prescribe for those 8 wks?

Even if your Vit D level was perfectly Optimal on completion of 8 wks of a loading dose, your level would be unlikely to remain Optimal if you've taken just 800 IU per day ever since. So I'd suggest re-testing and checking to see if you're in the Optimal range recommended by the 48 scientists in their PDF statement.

🖖🏻

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This was suggested twice by rheumatologist once in 2016 and again in July 2017. T his is some of what is written to my GP by Rheumatologist. We suggest high dose replacement therapy with 40,000 IU Cholecalciferol orally once a week for 8 weeks or a possible alternative 300,000 units of Cholecalciferol or .Ergocalciferol intramuscularly. Then the letter goes on about maintenance with Acal D3 twice a day .Does not state what strenght though.

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Matt,

I presume you took the 40,000 IU orally, for 8 weeks, which equates to slightly over 5,700 IU per day.

You then took Adcal D3 twice per day. There are m, it seems, two types of Adcal D3 on the Nhs. One ia 400 IU each, and the other is 200 IU each.

So you're either taking 800 IU per day, or 400 IU per day. If you're of average height and weight, both the 800 IU per day and the 400 IU per day are inadequate. Unless, of course, you happen to spend loads of time undressed in Barbados in the sunshine and without any sunblock lotion. 🤔

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Wheezybronch, thank you for your reply. It's correct that you do what feels right for you.

Best wishes. 🖖🏻

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Thank you very much, spreading relevant information is essential and you are doing a great job, thanks.

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I really have to go to bed, I am desperately tired, good night, been good talking.

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Thank you x

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Thank you hope you well also x

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Hi as others posters said .

I have endometrosis and had a CRP 124 once when I was having a massive flare up and needing an op . This was caused by inflammation.

Xx

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