New meds: I've just been prescribed... - Fibromyalgia Acti...

Fibromyalgia Action UK

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New meds

ladyhm profile image
25 Replies

I've just been prescribed duluxotine after trying everything else. Has anyone else had any success with this med. Nothing seems to help think this is a last resort. Soft hugs to you all.

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ladyhm profile image
ladyhm
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25 Replies
Janet28 profile image
Janet28

Hi ladyhm , I'm sorry I haven't used this drug myself but I'm sure other members will reply as I have seen it mentioned quite a bit on the forum.

It takes a long time to get meds right and even then our body changes and they don't have same effect.

I do wish you well and they help your symptoms.

Luv Jan x

ladyhm profile image
ladyhm in reply to Janet28

Thank you for your reply. I'm desperate now for something that will work. X

Trikki profile image
Trikki in reply to ladyhm

Oh dear.....I cannot help either...Never prescribed for me....Have you typed it into our search engine top right of the screen to see if there have been any other posts re. Duloxetine. Hope you are able to get some relief very soon....x

BlueMermaid3 profile image
BlueMermaid3

Hi ladyhm

Do you mind me asking what you are looking for from this med?

I was prescribed Duloxetine but I personally couldn't cope with the side effects.

I really should point out that I have tried just about every antidepressant there is and have only found one that I can tolerate.

I have a terrible intolerance to antidepressants and antibiotics.

The only way you will know if it is right for you is to see how you get on with it yourself.

I just wanted to be honest with you but I really do wish you all the very best of luck with it. There is no reason why it shouldn't work for you.

Wishing you much peace

Lu x

Administrator

neesey1005 profile image
neesey1005

hi I was put on duluxotine 3 months ago and i was very poorly for two weeks (also was coming off pregabalin) but now i am much better on the duluxotine, less pain in my legs and walking better Neese x

ladyhm profile image
ladyhm

I also have intolerance to antibiotics. Am hoping this med might take away the pain . What side effects did u have to suffer

neesey1005 profile image
neesey1005

I am allergic to pencillin and have intolerances - gluten, wheat, sugar, dairy, - I had awful side effects for nearly 3 weeks, and the doctor told me to keep with it - aches and pains flu like symptoms , fatigue was terrible - was in bed for a week - splitting headache and going hot and cold. - then I started walking better and less pain in legs and fatigue is better - I am glad I stuck with it but we are all different - good luck. x

ladyhm profile image
ladyhm

Thanks I'm going to start them tomorrow. Xx

TheAuthor profile image
TheAuthor

Hi ladyhm

I have never used this drug myself but I have pasted you a *Goolge search below:

*Duloxetine, sold under the brand name Cymbalta among others, is a serotonin–norepinephrine reuptake inhibitor. It is mostly prescribed for major depressive disorder, generalized anxiety disorder, fibromyalgia and neuropathic pain. Wikipedia

Molar mass: 297.4146 g/mol

CAS ID: 136434-34-9

I want to sincerely wish you all the best of luck with this and please take care of yourself.

All my hopes and dreams for you

Ken

Kathy70 profile image
Kathy70

I am just starting on it. My dr says it takes a few months to kick in. My daughter who also has fibro at age 28 has been on this for a while but says she does not feel it helps her overly much. Be very careful if you decide to stop taking this. they have just settled a lawsuit for problems with people coming off the medication.

BlueMermaid3 profile image
BlueMermaid3 in reply to Kathy70

Hi there

It usually takes about 6 weeks for an antidepressant to kick in.

Some do start working before then.

Lu xx

lilly60 profile image
lilly60

Hi I have tried Duloxetine it did not work for me I have tried several but cannot get on with them the thing is with me I like to "think"I am in control I don't like feeling like a" foggy zombie " only way I can describe it 😥😥

I do take celebrex 4 a day and was told by my specialist that if I have a night that I cannot bare I can take another 2 I did this at 5am this morning wish I had succumbed earlier but I do try to tolerate it 😥

Healing fibes to you all x x x

angiesmith50 profile image
angiesmith50

I have never tried those but I have been taking Fluxitine for depression for years. I don't get side effects. I go through short periods when I think I need something stronger but I don't want to move up the scale any farther if you know what I mean. But on the whole I'm happy with them x

Midnightstarr profile image
Midnightstarr

I was on this years ago and it didn't help me, but I have just started using a cream that really seems to be helping. To the point I am taking my med's a lot later than usual and I think I'm going to try and cut back on the tramadol I take. It's called Celafen. My daughter read an article on it and sent it to me. I've also let friends try it, that have muscle and joint pain and they have seen improvements too. Hope this helps

ladyhm profile image
ladyhm in reply to Midnightstarr

Thanks I might give that a try where can I get it from x

Midnightstarr profile image
Midnightstarr in reply to ladyhm

My husband Got it off the Internet for me. Really has made a difference.

Angelesc profile image
Angelesc

I would be really careful about getting an SNRI antidepressants prescription medication on the internet. GPs can prescribe it and it's approved for fibromyalgia so at least in Australia it's affordable. I took it years ago and seemed to help with pain for the 2 wks and as I kept taking it it made me more and more I'll. eg brain zaps, headaches, sweating all day and hot flushes.

My neuro put me on joncia which is the brand name- can't spell the chemical name! It's only been a few weeks and I'm supposed to go up slowly. Yesterday I came home late from work and took it late and had an early start at work and had a horrible time as with cymbalta for the whole day. I'm looking forward to going up on my dose if I'm going to have these side effects!

It's worth a try, everyone has a different reaction to meds! Good luck!

terri19 profile image
terri19

I have been on doloxatine for months, , I was put on them for neuropathic pain, but they are an antidepressant, I take 120mg, the only thing I notice is when I don't take them I go dizzy and feel really sick, so I think they are addictive. Worth giving them a chance , I think Iv tried nearly every tablet around for nerve and lower back pain good luck, hope they help 😜

ladyhm profile image
ladyhm

Thanks everyone I can but try them. Don't hold out much hope though xx

denvajade profile image
denvajade

Hi there I find this medication wonderful. 60mg 1 per day. Wishing you well

ladyhm profile image
ladyhm in reply to denvajade

Thanks for that, I feel a bit better now x

Maladjusted profile image
Maladjusted

Hi Ladyhm

As you know what suits one person doesn't necessarily suit another. I seem to be intolerant to most things my doctor offers.

However I have been taking Cymbalta (Duloxetine) for over 3 years and find that they help enormously. I began on 30mg per day to get used to them, then upped to 60mg. During a flare or on a day when the pain is particularly bad I will take 90mg, but go back down to 60mg as soon as I can so that my body doesn't get too accustomed to the higher dose.

I did initially have side effects such as nausea, bad headaches and inability to sleep, though I put up with it as it did help the pain in my legs.

That all seems such a long time ago now. I take my tablet every morning, no side effects now, and little if no pain. Taking it in the morning works best for me because if I take it too late I am unable to sleep. I also know very quickly if I have forgotten my tablet as I feel the pain building up in my thighs, so for me this drug works. I have heard the stories of how difficult it is to withdraw from, and will cross that bridge if I should come to it. However right now I have no plans to stop it because without it I can barely walk.

I hope it helps you. Good luck. Em xxx

ladyhm profile image
ladyhm

Thanks for that positive feedback, I'm still nervous of taking them but I will now give them a go from tomorrow. Regards helen

Lydia200 profile image
Lydia200

Hi

I'm currently reading a book called 'Fibromyalgia Your Treatment Guide by Christine Craggs-Hinton. It was published in 2013 and I believe she had another book since. Its really well written and explains different types of medication and self help things too. There's several types of pills to try. Often GP's give us antidepressants first.

I borrowed the book from the library. It's worth reading as you may find it useful.

I've tried about 5 types of antidepressants for fibromyalgia, each resulted in quite bad depression and feeling totally drugged up. I've decided that I'm not depressed chemically, I can make happy hormones. I believe thats why my brain chemistry reacted badly.

I'm in body pain, migrain pain and anxiety. So I'm in the process of working with a Rheumatologist and trying anticonvulsants.

Has your GP referred you to one yet?

Mine is very nice and understanding.

Also has your GP checked your Vitamin D and B levels? Low levels will heighten pain, depression and Fibro fog.

We also have to treat ourselves by lifestyle.

Don't give up, keep going, baby steps.

Best wishes

Lydiah

ladyhm profile image
ladyhm

Yes my rheumatologist suggested the duluxotine, have tried quite a few tablets I am intolerant to them all unfortunately, I take a vit d supplement and my b12 levels are fine so this tab hopefully will be the one lol

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