Hello. I'm a newbie to the site. I wonder if someone could put my mind at rest? I've been on 200mg of Sertraline for the past 14 years following a major work related breakdown. I've always been a bit concerned as I understand this is the max dose. I'm now having problems with chronic pain so my GP as today prescribed Amitrip: 10mg to start. Has anyone had experience of this "cocktail"? At the moment I take 100mg of Sertraline in the morning & the other at night. I've been told to take the Amitrip at night to help with sleeping so should I take 200mg Sertraline in the morning. Any advice greatly appreciated.