Feeling drunk after prometrium

[pursuitofhappiness1]

Hi Team!

i'm currently 6 weeks and 2 days pregnant. Because of my previous losses, I take lots of progesterone - 2 pessaries in the morning (200mg each) and 2 at night (200mg each). I also take Prometrium (100mg) during the middle of the day and find that I get a super tipsy/dizzy feeling about 1/2 hr after taking it. It lasts about an hour. Tbh, I don't mind it haha its kinda nice but I'm wondering - does anyone else feel like this? I've always had blood pressure that's kinda on the low side so I'm not sure if it lowers my BP even more?

Anyway, sorry if this doesnt make much sense. I'm writing in a prometrium-induced haze atm... keen to hear from fellow prometrium takers!

Cheers,

PoH x

[Purpledoggy]

Are you taking it orally? If so then it's the metabolites making you feel drunk - they act on the same receptors as alcohol and some sedatives like diazepam (Valium). It's a known 'thing' with oral and cutaneous progesterone administration due to the way they are absorbed and metabolised xx

[pursuitofhappiness1 in reply to Purpledoggy]

Hey Purpledoggy!

Thanks for your response!! That’s so interesting! Yes I do take orally.

Is cutaneous progesterone an injection? Or pessaries? Sorry I’m a noob 😞

[Purpledoggy in reply to pursuitofhappiness1]

Sorry, cutaneous meaning skin cream. You can get natural bioidentical progesterone cream in the US-I have some I tried as I have low progesterone and it makes me dopey after applying. When I noticed that effect I looked into the metabolism and why pessaries/injections don’t do it so much. Xx

[pursuitofhappiness1 in reply to Purpledoggy]

Wow how clever of you! Thanks for the insight x

[Cinderella5]

I've not taken the meds you're on but I tried utrogestan orally (as it was giving me trouble downstairs) and felt completely out of my face at work of all places!🙈🤣 Didnt try that again. I ended up only taking these at bedtime orally after that.xx

[pursuitofhappiness1 in reply to Cinderella5]

Hey! I didn’t realise we could take utrogestan orally! I take 4x200mg per day but vaginally so it def doesn’t make me feel drunk like the prometrium. As I said in my OP, I’m not entirely hating the feeling but I’m glad to know other ladies have felt it and there’s not something seriously wrong with me haha

Xx

[Cinderella5 in reply to pursuitofhappiness1]

I didnt feel like that when I used then vaginally....only orally! It was the oddest feeling!🤣 I couldn't have functioned. Its defo not just you!!xx

[pursuitofhappiness1 in reply to Cinderella5]

Hahaha thanks gal x