Looking for similar experiences here,
hope you ladies don’t mind. So our little euploid embryo (our last one!), which we had PGS tested last year, is now unbelievably 14 weeks! I need to pinch myself everyday - it has been an emotional roller coaster every week! Last week when we had our dating scan we did also the combined screening test, a test which measures the risks of the foetus to have Down Syndrome, Edwards and Patau syndrome. The test uses an algorythm and brings together age (in my case 44), the nuchal measurement of the foetus (which was normal) and the values of PAPP-A and Beta HCG from a blood test. My result came with a high risk, 1 in 11 chances of the baby having Down Syndrome. It is not a diagnosis, it is a rough measurement of risk, which could be high because of my age anyway or possibly also because I have been taking heparin, steroids, progesterone and oestrogen until a few
days before the test. We did the PGS on the embryo and it was confirmed that it was a euploid, so I am a bit shaken by this result. I am now presented with the choice of doing another test that can be more accurate in meausuring the risk, called PNTI (which is a simple blood test) and/or a diagnostic test, an amniocentesis, which is the only one which could really confirm a
diagnosis of DS or not. However the risk of miscarriage for an amniocentesis is 1 in 200 for IVF pregnancies.
Is anyone here facing similar circumstances? Has anyone done PGS on their embryo and then had a false positive for the combined screening? If so, how are you dealing with it all? I would be grateful for anyone sharing their experiences. I am trying to stay calm and it is not easy. And i don’t want the baba to feel in any way unwanted, if you know what I mean.
Thank you for anyone out there willing to share.