Started taking cyclogest too early - Fertility Network UK

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Started taking cyclogest too early

2nonblondes profile image
12 Replies

In the process of FET and had an appointment yesterday. Good news was that the lining is thick enough (10.5mm) and we were told to stop taking Buserelin injections and the clinic would call later that day about the next round of drugs.

We hadn't heard from clinic yesterday so started taking Progesterone and Cyclogest last night. We have spoken to the clinic today and now they say we have started taking them too early and we have to terminate this cycle.

The problem is that we were oestrogen medication for 8 days instead of the recommended 10. I spoke to the NHS earlier and we can probably force the issue and continue with the cycle. I feel whilst this is outside their regular protocol it still might work. Does anyone have any idea of how important those days of oestogen medication might be?

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2nonblondes
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12 Replies
Gueritarubia profile image
Gueritarubia

I’ve had three medicated FETs now and the only thing my clinic has been concerned about has been lining thickness. Due to calendars and availability, I’ve started taking progesterone anywhere from between day 9 of cycle (7 days of oestrogen) to 14 days. So I don’t think it’s a problem as long as you get a transfer five days after starting to take progesterone. Good luck!

2nonblondes profile image
2nonblondes in reply to Gueritarubia

Thanks Gueritaubia. Maybe it's a scheduling thing. I thought the estrogen was to thicken the lining so once that is good enough I did wonder why we need to wait to begin with cyclogest.

We were very disappointed to lose this cycle cause the clinic didn't call us back. It's with the NHS so we will go to the hospital on Monday and see what we can do.

Gueritarubia profile image
Gueritarubia in reply to 2nonblondes

It mUst be a scheduling thing. You’re right that oestrogen is to thicken the lining. Normally your body produces progesterone after you ovulate, and then the ideal timing for implantation is 5 days after ovulation. So, FET transfers are after five days of progesterone. You having started taking it, means the clock on when transfer should be is now ticking. I cross my fingers the clinic can squeeze you in!

KiboXX profile image
KiboXX in reply to Gueritarubia

Yeah I’d have to agree with it being scheduling. They always do transfers 5 days after starting progesterone so it might be they don’t have space for a transfer in 5 days but I would stamp my feet and make it happen as they didn’t get back to you when they were supposed to! Good luck x

Purplis profile image
Purplis

It depends on how old your embryos are - 3day or 5 day? If 3 day, then you ought to be having the transfer on Monday, I think? Hoping you get positive answers on Monday

2nonblondes profile image
2nonblondes in reply to Purplis

Embryos are 5 day. We have 2 and were planning to out them both in.

Cinderella5 profile image
Cinderella5

Hopefully they will be able to just transfer sooner than normal. It may be that they only do transfers on certain days and you need to transfer 5 day blastocysts after 5 days of progesterone. I do hope they manage to schedule everything ok!xx

2nonblondes profile image
2nonblondes in reply to Cinderella5

Thanks. Going to go to the hospital this morning and see if we can salvage this cycle. All of this half baked information we have been getting from them doesn't make sense so hopefully we can get to the bottom of it this morning.

Cinderella5 profile image
Cinderella5 in reply to 2nonblondes

Great news, good luck!xx

2nonblondes profile image
2nonblondes

So we met the consultant yesterday. She has told us that as we have started taking progesterone too early (albeit after the lining has developed to a sufficient level - 10.5mm) and that this upsets the cycle which is no longer in sync. She has told us that this upsets the success rate to around 10% so we have decided to cancel this cycle.

It is frustrating to cancel a cycle over something so stupid but so be it. We are going on a shorter protocol this time which means we can hopefully do the FET within just over 3 weeks.

NHS is so bad though. They had a different lining level on the system than the nurse had told us. So much different information from them you really need to on the ball dealing with them.

Cinderella5 profile image
Cinderella5 in reply to 2nonblondes

I'm sorry to hear that & not sure what is behind the reasoning but better to be safe than sorry!xx

RhinoCat profile image
RhinoCat in reply to 2nonblondes

What a nightmare 🙄, at least three weeks isn’t two months 👌🏻 Nicer to know reasons etc and now you have a plan to move ya forward. No embryos wasted ✅ you’ve still got this chance 😘🙏🏻💐💖

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