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Fertility Network UK
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Low amh, high fish and 40 years old

Hi there,

Anyone in similar situation and have had success?

We’ve completed 3 Ivf cycles without success. We’ve always done a short protocol, the first Ivf using gonal f and the other two using menupur. Daily injection 375. Always had something to transfer but low numbers collected (3,7 and 4) and low numbers fertilised (1 or 2). One of the cycles we used icsi but had low number fertilise so nothing to freeze. Not sure we’d bother using icsi again.

We’re looking to do another cycle in a couple of months so have stocked up on vitamins, dhea, royal jelly, Ubiquinol, high vitamin c and e, vitamin c, inositol. I’m rattling lol.

Any thoughts or your experiences would be welcome!! 😀😀

16 Replies
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Hey there! Hope you're doing good. I can totally understand what you're going through. Having no luck with the IVF cycles can be extremely saddening. I would suggest you try a different clinic. A known one who is famous for this treatment. A lot of people on this forum suggest a clinic in Eastern Europe try that out. Also, try changing your daily habits. Excercise and do yoga! Also, eat healthy vegetables and fruits. Drink water and be stress-free. Do your research and be more informed about this process. I hope this cycle goes well. All my best wishes are with you. Best of luck.

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Thank you so much for replying.

Just as you suggest we are going to try a different clinic for our next go, just waiting for them to receive the referral. It’s actually made me feel excited and hopeful again. Hoping a fresh pair of eyes will give us some much needed good luck.

We did think about a clinic well known for dealing with low amh in London but what with the travel, daily blood tests and huge costs they charge (3x what we have/will pay elsewhere) have decided to go somewhere within an hours drive.

Will take your advice and ensure I have lots of fruit and veg each day.

Hoping the dhea I’m taking will help with my amh/afc.

Best wishes

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Hi Jules, I would be careful with total jelly, my nutritionist advised against it and I have done some research to confirm this. Also, inositol only works well for PCOS so if you don’t have it, it may do more harm than good. You might like to read “It starts with the egg “ by Rebecca Fett. Good luck x

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*royal jelly

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Hey, thanks for your reply. What were the reasons royal jelly isn’t considered a good idea? I will defo stop if there is data to say it could have a negative impact. The info I’ve read regarding inositol is that it is good for pcos sufferers but is also good for people who’ve had previous failed ivf’s. It’s apparently good for the liquid in the egg and has helped with quality. x

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My nutritionist said that there is no good quality research to support the theory that royal jelly suppports human fertility. According to Fett it can be harmful as it contains some of the allergens found in bee venom. She also talks about studies in Italy where women without PCOS were given inositol before IVF and the number of mature eggs and embryos were reduced. Of course these are just my personal research, I’m not an expert but I thought I would mention it as you might want to dig a bit deeper. X

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Thanks for the info. I will definitely look into a little more. x

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I’ve conceived twice naturally in 3 months after being on inositol every day, i believe in it! Also 600mg ubiquinol per day xxx

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I should add I’m a low amh not a pcos case, so was just agreeing that inositol is good for egg quality x

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Thanks for sharing your experience. That’s great to hear it helped. How much did you take a day? I have the powdered form that you mix into water.

Wow 600mg is a lot. Was it definitely ubiquinol or coq10? I’m already taking quite a few tablets. I’m currently taking 200mg ubiquinol so would mean another 4 tablets!! Have you done Ivf, if so what was your amh level? My last check was 7. x

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I have Jarrow inositol powder and take a heaped teaspoon mixed in water every morning. And the ubiquinol - yes to 600! Some top places are recommending 1000mg but it’s is too expensive. I buy the 300mg capsules on amazon from the brand Health Thru Nutrition which is the best value and have one in the morning and one in the evening and I also take PQQ by the same brand as it enhances the effect of the ubiquinol xx

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Oh and my amh is around 2.8 (it has measured at 2.2, 4.6 and 2.87 so they are taking the middle value). I’ve done 2 failed ivfs but then had 2 pregnancies which is so sad but I guess promising xx

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What have the doctors said/recommended you do next? There is definitely hope, 2 pregnancies is great. Can I ask what egg numbers you had collected with your Ivf’s? What protocols did you do? Mine have been low and only half fertilise which is frustrating. Haven’t had one stick as yet. x

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I did 2 x short protocol, maximum dose ivfs on the nhs. 1st round disastrous and left me really disheartened - I had 7 follicles of a good size at trigger and by collection only 4 follicles and 2 eggs collected. Only 1 fertilised and arrested at day 2, so no transfer. The second cycle I had only 5 measurable follicles but got 4 eggs, 3 fertilised, 2 transferred at day 3 knowing they were poor quality and bfn. The 3rd embryo stopped developing at day 3. No Frosties. Then these two natural pregnancies were a shock but both ended at 5 weeks. About to try modified natural ivf now which is good for low ovarian reserve. I have an AFC of 8 x

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My clinic prefers long protocol and has very good success rates, is it worth trying this?

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I’ll definitely ask when we go for our consult with our new clinic. I always assumed the follicles would be too sleepy/ slower to grow after a long protocol. Mine take nearly two weeks of meds on short protocol to get to the right size and then I only have a few to collect.

Fingers crossed they come up with something new to try.

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