Nocturia...Waking up more than once at night to urinate

[rokks]

I can hardly sleep at a stretch...i have to wake up more than once ...sum tyms three-four times to urinate....I have endometriosis found on lap ...on zoladex injection...friends do you experience nocturia along with frequent urination and urge to urinate throughout the day??

[Impatient]

It may be a side effect of the zoladex. Check with your GP for any urinary tract infections and rule them out if that is the case or get them treated.

After that you need to consider whether to stay on zoladex or stop it and let your pituitary gland start waking up and producing the hormones that regulate the kidney function.

I've just copied and pasted the details i put on a recent post about which hormones are affected and can be shut down by zoladex ..

"Antidiuretic hormone (ADH (also called vasopressin) : this hormone is produced by the posterior or back part of the pituitary and is responsible for water and sodium (salt) balance. Deficiency of this hormone causes excessive and frequent urination and excessive thirst. If the patient does not drink an adequate amount of water, the blood sodium can increase abnormally and causes dehydration. Many patients can drink enough water to maintain a normal blood sodium level, but this is extremely inconvenient for the patient - having to drink large amounts of water (day and night) and urinating every hour or so to make up for the large urine losses from the kidneys."

Have a word with your GP about possibly getting HRT hormone replacement therapy for the missing ADH. It has risks, and you may want to look in to those and weigh up that against stopping zoladex.

[rokks]

Thanx for the reply...but i was facing this problem prior to the zoladex injection and was seeking for patients with similar experience i.e.frequent urination at night along with frequency althroughout the day

[Impatient]

You weren't clear on that side of things in the 1st post - about it happening prior to the GnRH.

After gynae surgery i had 17 months of trouble with the bladder, not in contol either retaining wee, and in pain or racing to the nearest loo, I was checked for a bladder prolapse at 1st with a urologist, but that wasn't the problem, then after trying a couple of different tablets for bladder spasms which is what my GP suspected given that I'd had surgery, I found oxybutynin really did help and stuck with those for most of the duration. buscopan didn't sort out my bladder but we are all different and it is worth trying a few drugs to see if any can ease up on loo trips. My record was 6 times to the loo in 60 minutes, I remember it well because we were out visiting relatives and frustrating just didn't cover it. I work in a school and was really struggling having to race off to the loo at such short notice. The Oxybutynin didn't cure or resolve the problem entirely but it did mean the bladder was relaxed and I could empty out more in one go which meant usually a longer wait till the next loo trip but when I got the urge there wasn't much notice and holding it in till i got to a loo was always a big struggle.

Bladder spasms can be triggered by infection, endo, surgery or trauma to the bladder which knocks the electrical signals out of rhythm and usually it is a temporary thing after a surgery, rectifying itself with in a few days to weeks, but sometimes it can take a great deal longer and some poor patients never get their bladder pulsations back in order.

There are plenty of things to try and see if they do help and different forms of the tablets too, so if at 1st one doesn't suit you, don't be shy about asking to try something else.

It is really common - I had to explain to my colleagues that I had a problem and 5 yes 5 of the female staff admitted they too had problems with bladders (all of them got their problems as a result of child birth.) It didn't matter what hour of the day or night, I fluctuated from retention to incontinence over days and couldn't seem to find the middle ground.

That is to say until one morning I woke up and i felt i wasn't needing to race to the loo. Just felt different and I decided not to take my tablet and see how i got on. and I haven't needed one since that day.

I know mine wasn't caused by zoladex because my surgery and zoladex were the same day and the bladder problems kicked in when i got home 3 days later before the zoladex had time to kick off and shut down hormones. I had had a catheter in during and after my surgery - which may or may not have been the trigger.

It was a long frustrating and embarrassing at times 17 months but i am delighted to be back to normal again. I spent a long time doing pelvic floor exercises as per instructions from the GP, but it didn't change a thing. So I can't from my own experience recommend that as a way to get back control.

Aside from zoladex for the endo, have you tried out any of the bladder pills yet? or been checked for a prolapse or tested recently for UTI?

Some infections can also cause the bladder electrical signals to go out of synch so that's always something to check for periodically too.

I had given up all hope of ever having normal bladder function, but it did sort itself out so I would advise that you do try things, and don't give up hope of it rectifying itself. It can happen, I'm living proof of that.

I don't have the plastic coated bottom sheet on the bed these days, we had one for my toddler nephew who occasionally came for a night's stay, and I ended up using it myself just incase of mishaps in the night...or indeed in the day time if I was having a nap.

Really hope you manage to find something to help give you an improved state of bladder control. It sure does rule your life when you have bladder probs.

[wp22]

Hi, I am with you on this one, up to 2weeks before my period I cannot stop peeing and my bladder wakes me up a few times a night. I wake up shattered. When I come on most symptoms go, thank god. X

[wp22]

I have endo on my bladder x