Why Cycling in and out of Nutritional Ketos... - Diabetes India

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Why Cycling in and out of Nutritional Ketosis Is Recommended. Burn fat for fuel.

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suramoStar
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This article has been originally posted on: January 19, 2018. It explains about the differences between the KETO and other low carb diets. The article has been edited for health and safety issues. A person can ask their doctor before starting any low carb or any diet/exercise routine change, first. If type 1, please consult your doctor and continue on your insulin. Low carb dieting doesn't cure type 1 Diabetes, but it helps with the blood sugar control. (Administrator's note)

Why Cycling in and out of Nutritional Ketosis Is Recommended. Burn fat for fuel.

Low-fat, high-carb diets prevent healthy mitochondrial function, thereby contributing to chronic diseases such as obesity, Type 2 diabetes, heart disease, Alzheimer’s, cancer and more

Studies suggest low-carb, high-fat diets — and eating less frequently — may be the answer to the obesity epidemic.

When your body is able to burn fat for fuel, your liver creates water-soluble fats called ketones that burn far more efficiently than carbs, thus creating far less damaging reactive oxygen species and secondary free radicals

Multiday water fasting activates autophagy, allowing your body to clean itself out, and triggers the regeneration of stem cells. Having as little as 200 or 300 calories a day is enough to abort the autophagy process.

Fasting has been shown to trigger the regeneration of the pancreas in both Type 1 and Type 2 diabetics — a testament to the regenerative power unleashed in your body when fasting.

The notion that your body needs to regularly consume glucose for energy has become a deeply ingrained myth. As a result of this misguided advice, obesity, diabetes, heart disease and cancer prevalence have all spiked, burgeoning into national if not global epidemics. The truth is, most long-term low-fat, high-carb diets prevent healthy mitochondrial function, thereby making a greater contribution to disease than most people are willing to even consider.

Dietary fats are actually the preferred fuel of human metabolism. In 2016, the British National Obesity Forum and the Public Health Collaboration issued a joint report on obesity based on the analysis of 43 studies, warning the policy to encourage people to eat a low-fat diet is having a "disastrous impact on health."1,2,3 According to the authors, the current guidelines have been manipulated and corrupted for commercial gain by the food and beverage industries, and are based on flawed science.

Low-Carb, High-Fat Diet and Reducing Meal Frequency Can Solve Many Common Ailments

In conclusion, the report suggests a low-carb, high-fat diet — and eating less by cutting out between-meal snacks — may be the answer to the obesity epidemic. The benefits of this type of diet is the primary focus, which guides you through seven engaging lessons to teach you how your body works at the molecular level, and how different foods affect your body.

Traditional weight loss advice suggests all you need to do is count calories, eat less and exercise more. Somewhat better recommendations specifically recommend cutting down on sugar. However, while many will initially lose weight doing this, it usually doesn't take long to gain the weight back. Before you know it, you're caught in a loop of yo-yo dieting. There's a better way. A great many of the disease epidemics facing us today could be turned around by educating people about the benefits of:

A diet high in healthy fats, moderate in protein and low in net carbohydrates (total carbs minus fiber)

Intermittent fasting

Longer water fasting

It's important to realize that calories are not created equal, and this is why counting calories doesn't work for weight loss and health in the long run. The metabolic effects of calories differ depending on their source — a calorie from a Twinkie is not equivalent to a calorie from an avocado or a nut. That said, excessive snacking is a significant contributing factor to obesity, so, to lose weight and keep it off, you may need to reduce your meal frequency.

The Case for Fasting

I recommend limiting it to two meals per day, either breakfast/lunch or lunch/dinner, within a six- to eight-hour window each day. This meal timing is a form of intermittent fasting, as by eating all your meals within a certain span of time each day, you end up fasting daily as well. Longer water fasts also offer powerful health benefits, although you need to work your way into them.

One strategy I've found to be extremely helpful is to gradually increase the time of your daily intermittent fasting until you're fasting 20 hours a day. After about a month of this, doing a four- or five-day long water fast will not be nearly as difficult, as you're already used to not eating for extended periods.

I was skeptical about water fasting for a long time, but after learning more about the metabolic benefits of it, the relative safety and testing it out for myself, I've become convinced it's a powerful tool that is vastly underutilized. The clarity of thinking alone, which occurs around Day Three or Four, makes it worth it.

That's not the only benefit though. Importantly, water fasting activates autophagy, allowing your body to clean itself out, and triggers the regeneration of stem cells. Remarkably, whereas low-calorie dieting will cause morbidly obese people to develop skin folds that must be surgically removed after significant weight loss, this typically does not occur when you lose the weight by water fasting. Your body actually metabolizes the excess skin as you go along, because it's in such efficient regeneration mode.

Even having as little as 200 or 300 calories a day is enough to abort the autophagy process, though, which is why I started doing complete water fasts. I now do a five-day water fast on a monthly basis, and since I was used to doing 20-hour daily intermittent fasting, I experienced no significant hunger at all. It was really pretty effortless right from the start.

If you're severely overweight or have Type 2 diabetes, water fasting may be the answer you've been looking for. Recent research confirms that fasting can effectively reverse Type 2 diabetes in a relatively short amount of time. Type 2 diabetics were placed on a severely restricted calorie diet where they ate just 600 calories a day for eight weeks.

By the end of their fast, all were disease-free and three months later, having returned to their regular diet, seven of the 11 participants were still disease-free. Fasting has also been shown to trigger the regeneration of the pancreas in both Type 1 and Type 2 diabetics— a testament to the regenerative power unleashed in your body when fasting.

Burning Fat for Fuel Improves Mitochondrial Function

Eating a diet low in net carbs and high in healthy fats and/or fasting will allow your body to burn fat rather than glucose as its primary fuel. This has the sought-after side effect of improving mitochondrial function, which is foundational for disease prevention and optimal health. The mitochondria within your cells are largely responsible for generating the energy (adenosine triphosphate or ATP) your body needs to stay alive and thrive.

They're also responsible for apoptosis (programmed cell death) and act as signaling molecules that help regulate genetic expression. When your mitochondria are damaged or dysfunctional, not only will your energy reserves decrease, resulting in fatigue and brain fog, but you also become vulnerable to degenerative diseases such as cancer, heart disease, diabetes and neurodegenerative decay.

Why Cycling in and out of Nutritional Ketosis Is Recommended

The devil's in the details, though, and an important yet rarely discussed facet of nutritional ketosis — which is when your body burns fat as its primary fuel instead of sugar — is feast-and-famine cycling. The reason for this has to do with the fact that long-term uninterrupted nutritional ketosis can trigger a rise in blood sugar by driving your insulin level too low.

This paradoxical situation can arise because the primary function of insulin is not to drive sugar into the cell, but to suppress the production of glucose by your liver (hepatic gluconeogenesis). If your blood sugar is high due to chronically and excessively low insulin, eating a piece of fruit or other sugar-containing food will actually lower your blood sugar rather than raise it. Your microbiome may also be compromised in the long term, as chronic low-carb diets will not optimally feed your gut flora.

All of this can be avoided by cycling in and out of nutritional ketosis, basically going through a one-day-per-week fast and one or two days a week of feasting, where you eat double or quadruple the amount of net carbs. Your body is designed to have the metabolic flexibility to use both glucose and fat for fuel. The problem is, when you eat a high-carb diet for a long period of time, your body ends up losing its ability to burn fat. The good news is, you can regain it by inverting the carb and fat ratios of your diet.

Fat Is Your Body's Preferred Fuel

When your body is able to burn fat for fuel, your liver creates water-soluble fats called ketones that burn far more efficiently than carbs, thus creating far less damaging reactive oxygen species and secondary free radicals. This is why being an efficient fat burner is so important for optimal health. Ketones also improve glucose metabolism and lower inflammation.

Recent research suggests a ketogenic (high-fat, low-carb) diet may even be key for reducing brain inflammation following stroke and other brain trauma. Chronic inflammation is a hallmark of most chronic disease, including pain-related conditions such as arthritis. As noted in one study, ketogenic diets appear to be helpful for inflammation-associated pain by:

Generating fewer inflammatory reactive oxygen species

Lowering the excitability of neurons involved in pain signaling

Boosting signaling of the neuromodulator adenosine, which has pain-relieving effects

How to Implement a Ketogenic Diet

To implement a ketogenic diet, the first step is to eliminate packaged, processed foods. The emphasis is on real whole foods, plenty of healthy fats and, initially, as few net (nonfiber) carbs as possible. This typically involves dramatically reducing or temporarily eliminating all grains and any food high in sugar, particularly fructose, but also galactose (found in milk) and other sugars — both added and naturally-occurring.

As a general rule, you'll want to reduce your net carbs to 20 to 50 grams a day or less, and restrict protein to 1 gram per kilogram of lean body mass. To make sure you're actually meeting your nutritional requirements and maintaining the ideal nutrient ratios, use an online nutrient tracker.

Beneficial Fats to Eat More Of

Another key to success is to eat high-quality healthy fats, NOT the fats most commonly found in the American diet (the processed fats and vegetable oils used in processed foods and fried restaurant meals). Just about any fat found naturally in food — whether animal- or plant-based — is in fact healthy for you. For example, saturated fat found in animal products and coconut oil:

Increases your large fluffy LDL particles, which are not associated with an increased risk of heart disease

Increases your HDL levels, which is associated with lower heart disease risk. This also compensates for any increase in LDL

Does not cause heart disease, as made clear in a large number of studies9,10,11,12,13,14

Serves as a "clean-burning fuel" for your brain and mitochondria, producing far less damaging free radicals than sugars and nonfiber carbs

Examples of healthy fats to eat more of include:

Olives and olive oil (look for third party certification, as 80 percent of olive oils are adulterated with vegetable oils.

Avoid cooking with olive oil; use it cold)

Coconut oil (excellent for cooking as it can withstand higher temperatures without oxidizing)

Animal-based omega-3 fat from fatty fish low in mercury like wild-caught Alaskan salmon, sardines, anchovies and/or krill oil

Butter made from raw grass fed organic milk

Raw nuts such as macadamia and pecans

Seeds like black sesame, cumin, pumpkin and hemp seeds

Avocados

Grass fed meats

MCT oil

Ghee (clarified butter); lard and tallow (excellent for cooking)

Raw cacao butter

Organic, pastured eggs

Harmful Fats to Avoid

The harmful fats you need to steer clear of are all man-made. This includes trans fats, which are pro-oxidant, and all highly refined polyunsaturated vegetable oils,15 which are high in damaged omega-6 and produce toxic oxidation products like cyclic aldehydes when heated. Vegetable oils promote oxidized cholesterol, which becomes destructive when entering your LDL particles.

Also, when consumed in large amounts, omega-6 polyunsaturated fats — and especially industrially processed ones — cannot be effectively burned for fuel. Instead, they're incorporated into cellular and mitochondrial membranes where they become susceptible to oxidative damage, which ultimately damages your metabolism. These harmful fats have been shown to:

Contribute to heart disease

Promote gut inflammation

Disrupt arterial blood flow through your brain

Deplete your brain of antioxidants

Attack the cellular architecture of your nerves and impair brain development through mutagenic effects on DNA and altered epigenetic expression.

Even with a regular, well-rounded workout routine, you may still find it an uphill battle to keep your body in its best shape if you’re not fully committed to changing your habits. It can be a real struggle, especially if you don’t know where to begin.

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HOBIEONE profile image
HOBIEONE

Keeping active is good for us all.

Mercmancouchto5k profile image
Mercmancouchto5k

This post has been really useful to me in my T2D journey. Thank you for posting.

Sandy001 profile image
Sandy001

Hi Suramo, Thank you for taking time to post thorough guide and benefits of intermittent fasting besides other valuable, thought provoking information. I really enjoyed reading it.

Really appreciate if you can respond to my questions.If you are on 20 hour fast daily, means you consume food within 4 hours? How many calories and what would your typical meal/meals consist of? Can you give a meal plan/times for a day please? And then you mentioned fasting just on water for a day. What does your week look like?

suramo profile image
suramoStar in reply toSandy001

The food you need to consume is low carb or keto. Calories are the same as recommended, 30% less than necessary.

We are here to discuss the principles of diet.Meal plans one can prepared according to one's preferences for the food items and availability of those items.

If you are entering a keto cycle initial few days you might have flu like symptoms but after 2-3-4 days those symptoms go away.

Sandy001 profile image
Sandy001

Principles are a result of scientific theory first and experimentation. But if someone has already tried it and can attest to it with practicing and share testimonies. That would be really helpful.

suramo profile image
suramoStar in reply toSandy001

Watch this video.

youtu.be/7lKGCdwN4-Q

Activity2004 profile image
Activity2004Administrator in reply toSandy001

Hi Sandy001,

Please consult your doctor before you go and change your diet plan to be on the safe side of things.

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