When does supplementation become toxic or counter-productive?

[Jdig]

My Dear Fellow Adventurers,

Firstly, thank you for the wealth of information and inspiration - having this commuity makes so much difference!

I have a question today, that I have already asked both my doctor and pharmacist (neither were able to help): as I add a new supplement every few months (usually as a result of a recommendation here, usually something that has been the subject of research posted in a respected journal, after a double-blind study), I wonder whether there are things I am taking that counteract others, or, worse still, become toxic in the swirl of products that form my ‘stack’.

Here they are:

C/L 25/100 4 times a day, plus an extended release at night

Lion’s Mane

Mannitol

Vitamin D3/K2

PEA (Palmitoylethanolamide)

sesamin

Co-Q 10

Curcumin

R-Alpha Lipoic Acid

NAC (N-Acetyl L-Cysteine)

MagEnhance

Ginkgo Biloba

Vitamin C

Mega Folinic

Vitamin B12

Melatonin (10mg)

Krill Oil

Cholestoff

Losartan

The last three are not for PD.

I’m also waiting to get a blood-level test for B1, B6, B9, B12, so that I can start taking Benfotiamine (100mg with 25mg of Thiamine HCL) 4x a day. I have previously tried much larger doses of B1 but haven’t yet found the right dose.

Lastly, I was taking a B-Complex supplement, but stopped it after finding levels of B6 were very high in a blood test (and I have peripheral neuropathy).

Many thanks for your thoughts - and if you have any information about a good supplement for general gut biome health, I would love to hear it!

Jonathan

[crewmanwhite]

Hi Jonathan

You really need guidance from a healthcare practitioner who has experience in treating the causes of Parkinson's.

While some of your supplements are helpful (assuming they are good quality and correct doses, etc), some are a waste of money and/or doing the same job as others.

Once you define the causes of your illness process (trauma, toxins and/or infection) you will be able to aim your supplement regimen more accurately and save some money while getting better results.

[Jdig in reply to crewmanwhite]

Thanks, John. I recently started reading your book, and am finding it very interesting.

[chartist]

Scroll down to the bottom of your post and you will see the word " More" . Click on the down arrow to the right of it and the drop down menu will give you the option to edit your post.

Art

[Jdig in reply to chartist]

thanks, Art. That was useful!

[Rafiki2]

Hi Jdig,

Have a look at the website examine.com this is a website dedicated to all sorts of supplements with many clinical tests as well. Unfortunately one needs to subscribe in order to get the full value of their information, but there is a lot one can find without subscription.

[Jdig in reply to Rafiki2]

Thanks Rafiki, looks like a great idea!

[Sydney75]

I subscribe to a site to check all supplements against meds and other supplements. It has been very informative and I have stopped some supplements because the benefit was not worth risk bc of other supplements and meds my HWP takes. He has PD as well as BP and cholesteral problems, (can't tolerate statins). I think it costs about $15 month for version I use (not a medical professional).

naturalmedicines.therapeuti...

Good Luck!

[Jdig in reply to Sydney75]

Thanks for that, Sydney, could be just what the doctor ordered, so to speak! Good luck to you and your HWP.

[Jdig in reply to Sydney75]

Hi Sydney,

I noticed you said your HWP had issues with statins, so I wanted to share my experience.

A supplement called Cholestoff seems to have helped my cholesterol levels: down 60 points over several months! This came after Covid shut down the gyms, so the improvement wasn’t the result of exercise. Perhaps you have already found something similar, in which case great!

Best wishes,

Jonathan

[Sydney75]

Thank you!