Doctors should use different therapies when treating older and younger CLL patients

[Cllcanada]

From Science Daily...

'Doctors should use different therapies when treating older and younger patients with chronic lymphocytic leukemia, according to a new study led by researchers at the Ohio State University Comprehensive Cancer Center.

Key conclusions include:

Fludarabine versus chlorambucil: Fludarabine improved progression-free survival and overall survival among patients younger than age 70 but chlorambucil tended to produce higher overall survival in patients older than 70.

Rituximab combined with fludarabine, versus fludarabine alone, improves progression-free and overall survival in both younger and older patients.

Alemtuzumab, aka Campath, ,consolidation therapy after chemotherapy or chemoimmunotherapy does not improve progression-free or overall survival in either younger or older patients.'

Article...

sciencedaily.com/releases/2...

Source

jco.ascopubs.org/content/ea...

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