Just for thought- i copied a paragraph from an article i read
The study was supported by AbbVie, the manufacturer of venetoclax. AbbVie also owns Pharmacyclics, the manufacturer of ibrutinib . Several authors report relationships with industry, including AbbVie, as detailed in the article. Wiestner reports grants from Merck, Pharmacyclics, and Acerta Pharma (member of the AstraZeneca group), outside of the submitted work.
Impressive to have both the big drugs
Celera sold the ibrutinib molecule to Pharmacyclics for 3 mil. Janssen (a subsidiary of J&J) joint ventured with Pharmacyclics to develop ibrutinib. That deal has paid Pharmacyclics about a billion over time.
Abbvie purchased Pharmalcyclics for 21 billion. That's what a blockbuster drug can do for a company.
Currently ibrutinib is owned by J&J and Abbvie.
There are a lot of small, start up companies out there who hire scientists in the hope of developing some great cancer drug or a cure for the cold. Typically when they are on to something they have to bring in one of the bigger companies who have large distribution channels. Celera pulled the trigger way too early. Pharmacyclics did a great job hedging their bet and keeping a piece of the action.
AstraZeneca has acalabrutinib and you can bet they will be sending waves and waves of supermodel looking sales reps into doctor's offices trying to steal market share from inbrutinib.
Abbvie is the former Abbot Laboratories
The origin of ibrutinib dates back to the 1950s with the discovery of BTK. It was discovered in 1952 by Colonel Ogden Bruton, a pediatrician at Walter Reed Army Hospital, who reported the first case of congenital agammaglobulinemia in an 8 year-old boy.
As I understand it, he was looking for a cure for children with the immune disease and although he never found a cure, he kept the samples he was working on. This research eventually led it to ibrutinib.
Thank you Colonel Bruton!
It's all about connecting the dots, baby...
What is I find so interesting about this story is how research can play such an important role, even when the research was for an original purpose.
nothing gets past you, Scott!
Me too - I've yet to see hide or hair of a supermodel ... I hope approve acalabrutinib in the UK soon, I did not realize that it came with such good side-effects.
Vertigo and Venclexta?
Cll, venclexta, and anemia
Factors affecting pricing for Ibrutinib and Venetoclax
Imbruvica and Heart Issues
