Hi! I am new here. Actually just found this site today. I am 78 years old and have been taking medication for osteoporosis for many years. Alendronate was taken for over 5 years and one of my bone density scans showed a slight improvement. My doctor decided to give me a drug holiday and I did not take anything other than vitamin D and calcium for almost 2 years. I then had another bone scan and it showed that I now had osteopenia.My doctor put me back on Alendronate. After a couple of months I began to have severe leg cramps/pain. I discontinued the alendronate and the pain went away. I was on and off the alendronate pills several times, each time the leg pain recurring. After one year my doctor sent me for another bone density scan and she said she was referring me to an endocrinologist as my T score was in the osteoporosis numbers. The endocrinologist says I must go on prolia and I cannot try any other oral medication. I am feeling negative about taking the prolia shots, after reading about all the possible side effects .I will be seeing my family physician soon to discuss this. Does anyone have any advice...it will be greatly appreciated. Thanks.