Its getting worse.

[TrippyMcGuire762]

So I upped my dose of sertraline on Saturday as my doctor recommended, but both last night and Friday night, my anxiety has been unbearable, especially at night. I know it can take 4-8 weeks for it to start taking effect, but it should help in the interim right? It just feels like its getting worse.

[Tempestteapot]

Trippy, can your doctor give you a short course of diazepam to help you get over the tough start up? It really can help a lot! Please give them a call if you haven't already been prescribed this -they won't mind you asking as my psych. regularly prescribes diazepam for start up on SSRI's for anxiety sufferers. Hugs! xxxxx

[TrippyMcGuire762 in reply to Tempestteapot]

Talked to the doc about it (as my doc is a friend's dad), apparently, drinking citrus beverages is not good. I did not know that. Well, gotta cut it out for a good long while to get things back to normal.

[Agora1 in reply to TrippyMcGuire762]

TrippyMcGuire762, Grapefruit is one of the "no no's" . I think it amplifies the dose??

[Tempestteapot in reply to TrippyMcGuire762]

Yes, Trippy! Grapefruit in particular causes Sertraline to be metabolised differently. Good luck! xxxxx

[TrippyMcGuire762 in reply to Tempestteapot]

Well, it wasn't grapefruit, it was lemonade, rather large quantities over about a week could have the same effect according to my doc.

[Bethxxany]

I've been taking sertraline for a while now but I'm starting to feel it's not working anymore as I'm still as anxious but I'm also really sad I'm thinking about asking my doctor to change my medication as it's been upped 3 times and I just don't feel it works have you been on this long or do you know of anything else that may work that I can speak to my doctors about

[Facm1]

How does drinking citrus beverages (orange juice) affect the anxiety? Is it the sugar or what about it? Person is having horrible increased anxiety/paranoid thoughts after upping the dose of sertraline from 50mg to 100mg and lowered back to 75mg. Drinking OJ twice a day but feeling better after drinking it.