lynparza : my dad failed zytiga and... - Advanced Prostate...

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lynparza

Chris52981 profile image
18 Replies

my dad failed zytiga and xtandi- he has a somatic BRCa 2 mutation and they are switching him

To lynpraza- I am a nervous wreck and just wondering if anyone has a positive experience with a parp - he’s 81 some normal heart issues that are stable- he has bone mets and the last two

Years they were stable and just recently mildly progressed. Any suggestions or positive thoughts would be helpful.

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Chris52981
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18 Replies
Lemonpower profile image
Lemonpower

One day at a time Chris. My dad is 80. He broke his leg, went rapidly downhill, and got nixed from radium 223 treatment he was supposed to start in April. Now I wonder whether all his chemo/treatments etc was worth it, it's made his bones so frail and he lost all muscle tone. Zytiga worked for him for less than a year. Now I'm just thankful every day he's still with us. Every day is a gift. There is so much suffering involved in this awful illness. At this point I want comfort and peace of mind for my dad above anything.

Try to focus dad on basics of living like keeping him busy, active and engaged. Keeping the mind engaged is possibly better than any drug.🙏

mrscruffy profile image
mrscruffy

I too am BRCA2 positive. Started Lynparza in December of 2023 and have had great luck with it. It worked quickly and effectively. Only SE I have to deal with is anemia which is annoying but manageable. Currently on a 3/4 dose to help with red and white blood cell count. See MO next month and am hoping to reduce dosage to half dose. Been great for me. Good luck to your dad moving forward. No new mets nor progression of existing ones. Also, this med is quite expensive, if you go to "AZ and Me" they have assistance programs. I make too much for low income program but was accommodated any ways. Have been receiving free meds for duration of treatment

Chris52981 profile image
Chris52981 in reply tomrscruffy

Awesome

To hear thank you so much I will

Look into it -

MarylandGuy profile image
MarylandGuy

I am on it after nubeqa stopped working. It is better than if I did not take it, but my psa is rising again. The side effects are manageable for me, but I may have to do other treatments.

davebliz profile image
davebliz

I’m BRCA2. Olaparib worked for me 8 months.

Lawrencee profile image
Lawrencee in reply todavebliz

what’s after that?

davebliz profile image
davebliz in reply toLawrencee

Well, I’m on Zoladex and Xgeva. Failed Zytiga. Had Radium223 and Docetaxal.

Chris52981 profile image
Chris52981 in reply todavebliz

Did you have a ton of side effects

Mormon1 profile image
Mormon1

get a second opinion.

Psaman profile image
Psaman

I have taken the same path. I’m 77 and have prostate cancer with bone Mets

I too went though all the pills and came to Lymparza. I had to Ween myself on to it for about a month. The hardest of drugs to that point but I got 2 years out of it.

Currently im on my 4 th round of Pluvicto

It’s a marathon. Your Dad has Plenty to go. Just support him. Your DRs are doing their job

Psaman profile image
Psaman

I’m doing it for 12 years

Chris52981 profile image
Chris52981 in reply toPsaman

Have you been on lynparza

Chris52981 profile image
Chris52981 in reply toChris52981

For a while and how

Was ur side effects

Psaman profile image
Psaman

it was highly poisonous to me. I could only do one a day

Chris52981 profile image
Chris52981 in reply toPsaman

Lynparza one day - or did u get 2 years

Chris52981 profile image
Chris52981 in reply toChris52981

Oh I see I’m

Sorry one pill a day

Chris52981 profile image
Chris52981 in reply toChris52981

Did that still

Control for the two years?

Psaman profile image
Psaman

yes it did

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