My husband recently had PET PSMA scan last Feb 4, 2019 after 6months of treatment with Zytiga+pred, Xgeva and Eligard. Below is the general impression of the scan and its a mixed result with more positives and MO also agreed with it (we take whatever positive we can get from it)
However, when it comes to the PSA result, from 33 in July 2018, it has come down to 0.889 in December 2018 and slightly went up in Feb 2, 2019 just before PET PSMA scan to 1.05 😔
PET PSMA result (Feb 4, 2019):
- Size of prostate became smaller (from 3.4x3.4x3.5cm in July 2018 to 3x2.5x2.6 in Feb 2019)
- Interval regression in size and number of the subcentimeter left paraaortic, bilateral iliac chain and pelvic lymph nodes
- General decrease in number of metastases in the ribs/vertebrae/pelvis
- Still no mass lesions seen in brain, head, neck, lungs
- Gallbladder, pancreas, spleen and adrenals are unremarkable
- one node in lumbar area increased in size and intensity (SUV 91.6)
- Some pelvic lesion and rib lesions increased in size and intensity
Now based on the latest PET PSMA scan results and PSA results, our MO suggested Xtandi or chemo (Docetaxel/Taxotere) if in case husband’s PSA continues to increase in March 2019. He still wouldnt suggest radiation due to a lot of side effects.
Now, my question is, will it be better to do chemo or Xtandi? Would Xtandi still work if Zytiga stops working?
Also, does the side effects of radiation outweigh the benefits which is the reason why our MO doesnt like to include it in our treatment protocol?
Appreciate any inputs I can get please.
Thank you in advance Pca warriors and carers!