Testosterone and PSA drop and sore nipples

[cancerking]

Prostatectomy Gleason 8, Lupron, and pelvic radiation. I am now off of Lupron and testosterone went up to 341 with a PSA of 0.014. Three months later the PSA rose to 0.025. I developed nipple soreness and started on tamoxifen. On my last test, the PSA dropped to 0.014 and the testosterone had dropped 266.

I assume the testosterone was being converted to estrogen, and therefore the sore nipples.

Question: Why did the testosterone drop? Was this associated with the estrogen?

If the estrogen is beneficial, should I stop the tamoxifen and put up with sore nipples?

[Tall_Allen]

I don't know why T dropped - it tends to fluctuate.

I'm not sure why you think the excess estrogen was beneficial. Your PSA is very low- suggest changing to a conventional PSA test (lowest value 0.1) so you don't drive yourself crazy reading things into random fluctuations.

[cancerking in reply to Tall_Allen]

Thanks for the insight. It is easy to fixate on numbers in the meaningless range. If "Tall_Allen" doesn't know why the testosterone dropped, then why am I concerned, You are respected. Thanks again.