Two questions

[Scootman]

I have been on lupron and casodex which worked for a while tried xtandi and did not work had 42 days of radiation now on Zytiga for about 3 months. Have had 2 rounds of sbrt in pelvis for mets in bone, Last sbrt oncologist mentioned that the one met they did not treat had grown and felt that the zytiga is probably not working even though psa is dropping slowly. My questions are he said that maybe starting chemo after I have bone scan and cat scan on thursday. How effective is chemo and secondly how bad are the side effects of the treatment. I have lived my whole life hearing people talk about chemo and how sick they were. This has me very concerned about chemo and was is there anything to combat side effects. I appreciate any input from others who have gone through this. Scootman

[Shooter1]

I've seen people on chemo for other cancers who have had a really bad time... The chemo for prostate is not usually that bad.. Mine before adding xtandi wasn't too bad, after adding xtandi it got tough. Most people don't take both together, but my PSA started rising during chemo. Whole different story. Ice feet and hands and listen to music or a book and relax.

[tango65]

Chemo seems effective when the new anti androgens fail and it is probable the best sequence instead of using other new anti androgen.

nejm.org/doi/full/10.1056/N...

This link has info about chemo for PC by a real expert:

grandroundsinurology.com/dr...

[j-o-h-n]

I've seen many posts here where members said it wasn't a piece of cake.... but more like a donut.... (gotta make sure you don't drop it)....

Good Luck, Good Health and Good Humor.

j-o-h-n Wednesday 01/06/2021 12:01 AM EST

[bhr17]

I had no problems with Chemo except I had them back off some of the steroids as I was lit up for a week afterwards