New to site: My husband is 76 years old... - Advanced Prostate...

Advanced Prostate Cancer

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My husband is 76 years old. In 2017 his Ps a was over 200. He went though all the normal test, his gs was 4+5, his urologist said his bone scan lot up like a Christmas tree. Stage 4 prostate cancer. He was put on casodex and started lupron shots. Two months later his Ps a was not going down much, the oncologist started him on zytiga and prednisone. He was doing much better, he gained weight and was feeling his normal self. He was also given xgeva shots. October of 2018, the treatments stopped working, he started taking xtandi, his Ps a was still going up, did more scans. Cancer spread much more. He just received his first shot of xofigo. He is still losing weight and has no energy. Next week he gets a blood test for his Ps a and blood count. I take this one day at a time. I know that not all prostate cancer victims have the same experience but I would like to hear more stories like mine.

12 Replies

Dr. Sartor in New Orleans LA. is doing a trial for LU-177

Also I would call Dr. Bob Leibowitz in Ca. he has had great results with advanced PCa patients / many with worse situation than you described -- but I would move asap.

All the regulars on here have seen this -- but you probably have not

There are many clinical trials. You might particularly consider the VISION trial of Lu-177-PSMA-617. Check the locations list - there's probably one not too far from you:

We live in Wisconsin

I guess the site at Northwestern in Chicago is closest

I wonder if chemo has been discussed after failing Zytiga and Xtandi. You could talk with your oncologist about chemo.

Sometimes adding indomethacin could prolong Xtandi efficacy.

There are also clinical trials for abiraterone and enzalutamide plus niclosamide. Niclosamide could make the cancer to respond again to enza or abi.

The oncologist thinks he would do better on xofigo. Told us about the options and we decided the xofigo.

i had provenge but ones psa has to be lower. u know trial is the only way if hes been through all of it. 76 is a good year what does his doc suggest clinical trials is most likely the way to go now.


Always hurt when I read that the monster is fighting another brother, has he had chemo. That’s the first thing they did on me. Good luck and keep us informed. 🙏🙏🙏🙏🙏

No chemotherapy yet, think if the xofigo doesn't work that will be the next step.

Greetings again Mama... Keep on Keeping on. Remember God is on your side.

Good Luck, Good Health and Good Humor.

j-o-h-n Wednesday 04/17/2019 6:35 PM EDT

Mamabakes994 in reply to j-o-h-n

Thank you j-o-h-n! Yes, I know God is in our side. Good luck to you!

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