Experiences with

Xofigo

I asked if I could do Provenge and Xofigo together and he said no. He still pushes for that first instead of docetaxel. I asked him if we could do xofigo directly after the Provenge and he seemed agreeable to that.

cid=eb_govdel https://clinicaltrials.gov/ct2/show/NCT04206319 Xofigo is radium 223 but Xofigo is indicated and approved for the treatment of patients with castration-resistant prostate cancer, symptomatic bone metastases and no known visceral metastatic disease..

Xofigo was suggested I will see a prostate specialist Tues. To discuss the new game plan I am concerned chemo is a big commit to be have such a PSA uptick. Any have anything to add as other possible treatment plan or combinations with xofigo or something else .

Several years ago it was prominent in the news; now seldom mentioned other than Xofigo which is not a primary treatment, but rather palliative for pain.

Looking for anyone's experience with Xofigo, and preferably with Xtandi. And feedback appreciated!

Hello Warriors, since taking Xtandi 3 months ago, my PSA is now undetectable. it was up to 6.5 which my Onc recommended doing Xofigo. Now my Onc wants to hold off on it. my body has adjusted to it with less fatigue. Life is good. wishing everone a great summer. Keep fighting Nick

They will do a PET scan to make sure it hasn't spread to organs and start Xofigo 30th April. The would have started the Xofigo next week but they said this Virus crap makes everything logistically more complicated.

His platelets were extremely low, due to bone marrow failure caused by his Xofigo treatments ( recent research indicates patients like my husband may have up to a 45% chance that Xofigo will cause bone marrow failure! - had we known this, we would have taken a pass on Xofigo!

Hussain again on August 6th to decide what's next, but she mentioned both Xofigo and Jevtana as options. (I'm also going to push to switch to dexamethasone before we give up on Zytiga.) Dr. Hussain sounded like she favors Xofigo.

MO is suggesting Xofigo as next step, based on recent scans that show Mets have small increase since first scans to bones but no soft tissue spread.

Topics include: treatment sequencing, side effects, fears of chemotherapy, Docetaxel, Xofigo, Abiraterone, Enzalutamide, CARD trial, and Provenge. https://www.onclive.com/insights/chemotherapy-in-metastatic-prostate-cancer/maintaining-quality-of-life-in-metastatic-crpc

What about Xofigo as a next step? My MO did not mention it and just wants to keep me on Firmagon and see how things go. Any thoughts?

Casodex, lupron, taxotere, Zytiga, Xtandi, Keytruda, cabazitazel + carboplatin, xofigo (1 dose). Adenocarcinoma and neuroendocrine. PC now in his bone marrow. Trying low dose cabazitazel. Anyone done the same? He so tired.

He also highly suggested Xofigo. I'm not experiencing any bone pain but due to the rising PSA, I will pursue it. I finished my 3 infusions of Provenge 3 months ago. Others here believe that having Provenge and xofigo is beneficial.

My docs are hitting me with Lupron/Zytiga, Provenge, SBRT to the bone mets, Xgeva, and eventually Docetaxel and Xofigo.

Unfortunately, some of us here have been suspecting this, due to personal experience: "Twenty-three patients received Xofigo at UF Health, and one was lost to follow-up. Sixteen patients (73%) completed the full course (six doses) of Xofigo, while six did not.

We are going to be receiving our 4th Xofigo treatment. Can anyone fill us in as to what happens from here? We just had a scan. Still no Mets in the soft tissue just the bones. We would just appreciate some honesty. Should we be looking to go to Germany for treat with LU177?

My doc and I agreed to take Xtandi again for 2 months or so to see if it can attack the PSA again, then to consider Xofigo radiation to attack the bones. Do you folks have any suggestions?

Anyone out there have experience with these two drugs together or for that matter Xitiga with Xofigo? Steve in Maui

I guess cost wasn't in the insurance reps mind as Xofigo is 130k where chemo would be 20k. My headstone will read "im here because insurance wouldn't let me have life saving treatment" First injection done today, so far so good. PS. got results back from Gardant.