Fairly active 70-yr old, Dx 18 months ago, Gleason 10, several bone and lymph node mets. On Lupron since Dx, chemo & RP in first 8 months. PSA now undetectable for almost a yr, testosterone <3 ng/dl. For the first year, mild side effects of ADT: hot flashes, shrinkage of "the boys", etc. But starting ~6 months ago, I began to have what I can best describe as "creakiness". No constant pain, but I stiffen up when lying down or sitting for awhile, and hurt all over when I get up, until I get moving again. The creakiness is getting worse with time, and it feels like I've aged 20 yrs in the last 6 months. I'm scheduled to have my 1st prolia treatment in a couple of days, & I read that a common side effect of prolia is joint stiffness and pain. Yikes! Another 20 years next week?
When I describe the creakiness, my MO who give me the lupron says only "You can blame that on us." Likely so. You guys have any ideas about what might help me with it? Alligator blood, cannabinoids, or...? I take Crestor, aspirin, vitamins C & D3, curcumin, ursolic acid, resveratrol, astaxanthin, fish oil, melatonin, sometimes zinc, and hope to start metformin soon.