DX 7 yrs ago at age 54 with several bone mets, PSA in 40s and Gleason 9. Went on Lupron and Zytiga INTERMITTENTLY for 5 yrs with 3 "vacations". (also, had prostate removed along with >30 lymph nodes). After last vacation, my doc allowed the PSA to rise to 5.2 and 1-2 mets showed slight increase and a met in lymph node may have developed, (I wish "we" hadn't let the PSA go up so much before ending my vacation). I re-started Lupron. My old doc stopped seeing patients and my new doc took me off the Zytiga. I continued to respond to Lupron (without Zytiga) for 2+ years, with PSA dropping over time to <.05., until: Oct/19 PSA .08 Then, 2 weeks later in Oct.19 , PSA rose to .12.
Zytiga added to Lupron results: PSA went to .08, .08, .10. and back up to .12. in 2 week intervals. I assume PSA will be .16 or higher when tested again next week.
So- it appears as though the PSA will continue to rise with both the Lupron and Zytiga. Doc wants to continue with the same treatment and scan me in 6 months.( I think scan should be sooner.) Wondering what next step(s) should be and when. If scans show changes, do I take Docetaxel? OR something else. I appreciate your responses.