2012-Urologist biopsy with Gleason 9; (2012)-Dattoli Cancer Center, Sarasota, FL for Color Dopler affirmative PCA; 8 weeks Conformed Radiation, seeding, follow-up radiation; ADT. (2014) PSA doubling-Sand Lake Imaging Pet,CT/MRI, Ferheim (sp) imaging-no mets found. Continued ADT and supplements+Metformin. Oct 2015 off of Lupron and Casodex, still on supplements. Jan 2016 PSA doubling, back to Sand Lake Imaging-CT/MR AND F-18 Pet Bone Scan-Positive Met indicators of Pelvic and T5 & T8. Scheduled for Zytiga and prednisone, Xrelto and patch, back on casadex, and remain on Metformin, Avodart, flomax....... then???