Experiences with

Avodart

We had a discussion about Avodart and he said he would consider a prescription if I could show him persuasive studies. The following 5 are the best I could find. Does anyone have a favorite study that helped them convince their MD to prescribe Avodart?

6 PCa , I stopped Avodart for one month 2 years ago .

hence their is no need for Avodart? Component DHT, LC-MS/MS Your Value <2.5 pg/mL Standard Range 106.0 - 719.0 pg/mL http://www.theprostateadvocate.com/pdf/DIHYDROTESTOSTERONE%20DHT%20CONTROVERSY.pdf

I know there are oral meds out there such as avodart. Anyways, when I got home after the scope, I was not able to urinate. I rushed myself to ER and they put a catheter. it's discomforting but I'll take it in emptying my bladder. God bless you all. Nick

However, from what I know, Avodart will inhibit the final step that results in DHT. How often is Enzalutamide [Xtandi] resistance due to intratumor DHT? I don't know, but Avodart is an inexpensive safety play.

PSA under Avodart had been running around 2.0 since 2014. Had a follow-up biopsy in 2014, 18 core, was negative, but received a severe infection, prostatitis from it. Almost went sepsis, because they had me on CIPRO, and the e-coli infection was resistant to fluoroquinolones.

They said the size of my prostate even after 12 years of Avodart precludes me having brachytherapy. RO and MO said they can treat me with “ curative intent “ as shown in STAMPEDE trial.

PSA before - 4.0 PSA after - 0.3 He has been able to control with Avodart, Casodex and Metformin. 06/27/18 started Lupron when PSA was 1.1 10/16/19 started Xtandi PSA 9.3 6/16/21 Pet CT PSMA mets to liver.

I know we have some members who will vouch for the effectiveness of Avodart in managing their own disease state.

Another escape pathway is the manufacture of DHT (dihydrotestosterone) via the alternate pathway that does not require testosterone, Avodart will inhibit that.

FYI, apart from statins, Avodart and a long list of supplements I am not under any treatment.

I have not had Avodart but might consider it down the road. My main complaints about Lupron include: decreased metabolism leading to obesity, loss of muscle mass, loss of bone density, fatigue and lethargy.

I haven't really seen anything on this since Patrick (pjoshea13) had written about it a few years ago: https://healthunlocked.com/advanced-prostate-cancer/posts/139885449/dutasteride-avodart-abiraterone-zytiga Has anyone discussed it with their docs? I plan to, later this week.

Again slow rise and I off and on used Avodart and Casadox during the last three years. Had two 68 GL PSMA in the last three years which came out negative. Now I am planning to start EstroGel therapy. Had been closely monitoring the progress of some of the esteemed members who are on this group.

I am Al Mayo from canada .I am 86 years old .I have been fighting with my urologist for the past 17 years not to get a biopsy .My psa last Dec was 52.2 and I still refused a biopsy .I have taken many herbs and they work for awhile then stop.My urologist put me on avodart last Jan and he said that if

I use Avodart as do some of Ar. Myers ex-patients. "Overall, 943 males were enrolled; 45 (4.77%) were exposed to 5ARI.

George71 in reply to kaptank neither Avodart or finasteride are blocking the cells from getting testosterone -- nor are they blocking you from making testosterone -- they only keep you from converting testosterone to DHT. Kaptank: I don't know the answer and cannot find it in the literature.

[1] Note: 5α-Reductase Inhibitors [5ARIs] - such as Dutasteride [Avodart] - inhibit the conversion of testosterone to dihydrotestosterone [DHT]. "SARS-CoV-2 has a disproportionately severe effect on men, suggesting that the androgen pathway plays a role in the disease.

I see that a lot of members here are taking Avodart to reduce DHT level (5-alpha-reductase inhibitor) and since it is hard to get this medication without a prescription, I searched for herbal replacement such as: 1) Pumpkin Seed 2) Saw Palmetto 3) Green Tea 4) Giant Dodder 5) Reishi mushroom 6) Fatty

Dr wants me to take avodart to shrink prostate. Don't care for sounds of possible side affects. What are the other and best options? New Dr would prefer it smaller before next biopsy due to very large.