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Intemittent hormone therapy with orgovyx (relugolex) plus nubequa and avodart
Anyone doing this and what’s your protocol and how are you doing. Iam going on my third month this Friday. Psa went from 3,5 to .8 in the first mo.
Anyone doing this and what’s your protocol and how are you doing. Iam going on my third month this Friday. Psa went from 3,5 to .8 in the first mo.
rococo
in
Advanced Prostate Cancer
6 months ago
Is this a rare event?
Saw Tanya Dorff in USC and was put on triple hormone therapy with 90 day lupron. and Casodex and
Avodart
Dorff believed in intermittent therapy and was i was given a holiday from treatment if psa and testosterone were hormone sensitive between 9 months to a year until psa started its climb.
Saw Tanya Dorff in USC and was put on triple hormone therapy with 90 day lupron. and Casodex and
Avodart
Dorff believed in intermittent therapy and was i was given a holiday from treatment if psa and testosterone were hormone sensitive between 9 months to a year until psa started its climb.
arizonablue
in
Advanced Prostate Cancer
4 months ago
Wondering which arm of STAMPEDE dictated my 18 to 16 month ADT plus Zytiga treatment plan ?
Taking
Avodart
for ten years and doing many lifestyle changes per Snuffy Meyers kept my PSA low for a decade but when I stopped
Avodart
for a month 3 years ago PSA began to rise .
Taking
Avodart
for ten years and doing many lifestyle changes per Snuffy Meyers kept my PSA low for a decade but when I stopped
Avodart
for a month 3 years ago PSA began to rise .
PBnative
in
Advanced Prostate Cancer
1 year ago
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Dutasteride and Apalutamide
Is there any support for taking
Avodart
with Apalutamide to extend castrate sensitivity? I have been on Lupron/Apalutamide for >2 years now. Are there any studies that suggest Lu177 is effective in a castrate sensitive patient?
Is there any support for taking
Avodart
with Apalutamide to extend castrate sensitivity? I have been on Lupron/Apalutamide for >2 years now. Are there any studies that suggest Lu177 is effective in a castrate sensitive patient?
Squirrel71
in
Advanced Prostate Cancer
11 months ago
Avodart / Dutasteroid
We had a discussion about
Avodart
and he said he would consider a prescription if I could show him persuasive studies. The following 5 are the best I could find. Does anyone have a favorite study that helped them convince their MD to prescribe
Avodart
?
We had a discussion about
Avodart
and he said he would consider a prescription if I could show him persuasive studies. The following 5 are the best I could find. Does anyone have a favorite study that helped them convince their MD to prescribe
Avodart
?
Scout4answers
in
Advanced Prostate Cancer
1 year ago
DHT lab report
hence their is no need for
Avodart
? Component DHT, LC-MS/MS Your Value <2.5 pg/mL Standard Range 106.0 - 719.0 pg/mL http://www.theprostateadvocate.com/pdf/DIHYDROTESTOSTERONE%20DHT%20CONTROVERSY.pdf
hence their is no need for
Avodart
? Component DHT, LC-MS/MS Your Value <2.5 pg/mL Standard Range 106.0 - 719.0 pg/mL http://www.theprostateadvocate.com/pdf/DIHYDROTESTOSTERONE%20DHT%20CONTROVERSY.pdf
Scout4answers
in
Advanced Prostate Cancer
1 year ago
High intratumoral dihydrotestosterone is associated with antiandrogen resistance in VCaP prostate cancer xenografts in castrated mice
However, from what I know,
Avodart
will inhibit the final step that results in DHT. How often is Enzalutamide [Xtandi] resistance due to intratumor DHT? I don't know, but
Avodart
is an inexpensive safety play.
However, from what I know,
Avodart
will inhibit the final step that results in DHT. How often is Enzalutamide [Xtandi] resistance due to intratumor DHT? I don't know, but
Avodart
is an inexpensive safety play.
pjoshea13
in
Advanced Prostate Cancer
1 year ago
Non - metastatic (per PSMA-PET ) but high risk due to PSA 61 . Am I hastening CRPC with ADT and Zytiga
6 PCa , I stopped
Avodart
for one month 2 years ago .
6 PCa , I stopped
Avodart
for one month 2 years ago .
PBnative
in
Advanced Prostate Cancer
1 year ago
After Active Surveillance since 2013, time to explore treatment options
PSA under
Avodart
had been running around 2.0 since 2014. Had a follow-up biopsy in 2014, 18 core, was negative, but received a severe infection, prostatitis from it. Almost went sepsis, because they had me on CIPRO, and the e-coli infection was resistant to fluoroquinolones.
PSA under
Avodart
had been running around 2.0 since 2014. Had a follow-up biopsy in 2014, 18 core, was negative, but received a severe infection, prostatitis from it. Almost went sepsis, because they had me on CIPRO, and the e-coli infection was resistant to fluoroquinolones.
Yearofthecow
in
Prostate Cancer Network
1 year ago
Catheter
I know there are oral meds out there such as
avodart
. Anyways, when I got home after the scope, I was not able to urinate. I rushed myself to ER and they put a catheter. it's discomforting but I'll take it in emptying my bladder. God bless you all. Nick
I know there are oral meds out there such as
avodart
. Anyways, when I got home after the scope, I was not able to urinate. I rushed myself to ER and they put a catheter. it's discomforting but I'll take it in emptying my bladder. God bless you all. Nick
Nicnatno
in
Advanced Prostate Cancer
1 year ago
Questions for 2nd Meeting with MO tomorrow about reaction to 2 months on Orgovyx and Zytiga
They said the size of my prostate even after 12 years of
Avodart
precludes me having brachytherapy. RO and MO said they can treat me with “ curative intent “ as shown in STAMPEDE trial.
They said the size of my prostate even after 12 years of
Avodart
precludes me having brachytherapy. RO and MO said they can treat me with “ curative intent “ as shown in STAMPEDE trial.
PBnative
in
Advanced Prostate Cancer
1 year ago
Darolutamide & Simvastatin?
Another escape pathway is the manufacture of DHT (dihydrotestosterone) via the alternate pathway that does not require testosterone,
Avodart
will inhibit that.
Another escape pathway is the manufacture of DHT (dihydrotestosterone) via the alternate pathway that does not require testosterone,
Avodart
will inhibit that.
pjoshea13
in
Advanced Prostate Cancer
2 years ago
Looking for anyone else with the RAD51B mutation with mets to liver.
PSA before - 4.0 PSA after - 0.3 He has been able to control with
Avodart
, Casodex and Metformin. 06/27/18 started Lupron when PSA was 1.1 10/16/19 started Xtandi PSA 9.3 6/16/21 Pet CT PSMA mets to liver.
PSA before - 4.0 PSA after - 0.3 He has been able to control with
Avodart
, Casodex and Metformin. 06/27/18 started Lupron when PSA was 1.1 10/16/19 started Xtandi PSA 9.3 6/16/21 Pet CT PSMA mets to liver.
Dadslove
in
Advanced Prostate Cancer
2 years ago
Anyone taking a 5ARI (dutasteride/finasteride) with Abiraterone?
I haven't really seen anything on this since Patrick (pjoshea13) had written about it a few years ago: https://healthunlocked.com/advanced-prostate-cancer/posts/139885449/dutasteride-
avodart
-abiraterone-zytiga Has anyone discussed it with their docs? I plan to, later this week.
I haven't really seen anything on this since Patrick (pjoshea13) had written about it a few years ago: https://healthunlocked.com/advanced-prostate-cancer/posts/139885449/dutasteride-
avodart
-abiraterone-zytiga Has anyone discussed it with their docs? I plan to, later this week.
noahware
in
Advanced Prostate Cancer
1 year ago
Impact of Dutasteride on PSA Kinetics and Time to Progression in Men with PSA-only Recurrent Prostate Cancer - medRxiv - pre-pub May 5, 2021
I know we have some members who will vouch for the effectiveness of
Avodart
in managing their own disease state.
I know we have some members who will vouch for the effectiveness of
Avodart
in managing their own disease state.
cujoe
in
Fight Prostate Cancer
2 years ago
No adverse effect from the covid vaccine to my PSA
FYI, apart from statins,
Avodart
and a long list of supplements I am not under any treatment.
FYI, apart from statins,
Avodart
and a long list of supplements I am not under any treatment.
Justfor_
in
Prostate Cancer Network
2 years ago
5α-Reductase Inhibitors are Associated with Reduced Risk of SARS-COV-2 Infection
[1] Note: 5α-Reductase Inhibitors [5ARIs] - such as Dutasteride [
Avodart
] - inhibit the conversion of testosterone to dihydrotestosterone [DHT]. "SARS-CoV-2 has a disproportionately severe effect on men, suggesting that the androgen pathway plays a role in the disease.
[1] Note: 5α-Reductase Inhibitors [5ARIs] - such as Dutasteride [
Avodart
] - inhibit the conversion of testosterone to dihydrotestosterone [DHT]. "SARS-CoV-2 has a disproportionately severe effect on men, suggesting that the androgen pathway plays a role in the disease.
pjoshea13
in
Advanced Prostate Cancer
2 years ago
TRUP vs. alternatives
Dutasteride (
Avodart
) and finasteride (Proscar) are two types of 5-alpha reductase inhibitors. You’ll generally have to wait three to six months for symptom relief with 5-alpha reductase inhibitors.
Dutasteride (
Avodart
) and finasteride (Proscar) are two types of 5-alpha reductase inhibitors. You’ll generally have to wait three to six months for symptom relief with 5-alpha reductase inhibitors.
Scout4answers
in
Advanced Prostate Cancer
2 years ago
Eleven Years Updates. Starting EstroGel.
Again slow rise and I off and on used
Avodart
and Casadox during the last three years. Had two 68 GL PSMA in the last three years which came out negative. Now I am planning to start EstroGel therapy. Had been closely monitoring the progress of some of the esteemed members who are on this group.
Again slow rise and I off and on used
Avodart
and Casadox during the last three years. Had two 68 GL PSMA in the last three years which came out negative. Now I am planning to start EstroGel therapy. Had been closely monitoring the progress of some of the esteemed members who are on this group.
KSK54
in
Advanced Prostate Cancer
2 years ago
Side effect comparisons: Adovart vs Lupron
I have not had
Avodart
but might consider it down the road. My main complaints about Lupron include: decreased metabolism leading to obesity, loss of muscle mass, loss of bone density, fatigue and lethargy.
I have not had
Avodart
but might consider it down the road. My main complaints about Lupron include: decreased metabolism leading to obesity, loss of muscle mass, loss of bone density, fatigue and lethargy.
ron_bucher
in
Advanced Prostate Cancer
2 years ago
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