I split it initially but after a few years I found it made no difference if I took it in one daily dose so I’ve done that since. It’s better absorbed taken at night before bed rather than first thing in the morning , but some find sleeping an issue with night time dosing I just fall asleep the minute my head hits the pillow! Low ferritin caused me to have a serious afternoon slump but yours is excellent .
As you don’t take it at night I’d try that, as a bit extra might make the difference you need
there is a very good explanation written by diogenes(on this community) from 2 yrs. ago re: NDT It is entitled: Pharmacokinetics of NDT. If you can't find it, I'll do some cut & paste. I have been on NDT for most of my Ord's/Hashi life (35yrs). I have, only, ever taken it once daily in the a.m.
So if I understand the post correctly, it says that with T3 from NDT you do NOT get the boost you get from synthetic T3? And that it does a lot longer to break down and enter the bloodstream.
So it doesn’t matter what time of day you take it?
My own experience of taking NDT agrees with the slower release of hormone compared to the synthetics. For me, it's a 'smoother ride', meaning I don't feel my levels peaking in the way it can feel with synthetics. But I wouldn't say that's a reason not to split the dose. Tolerance of thyroid hormones can vary from one person to another. Some people can tolerate it all in one go, others need to split dose. Actual time of day isn't necessarily important (as long as enough time is left before/after eating etc.), but consistency is best.
3.75 grains is quite a high dose. Most people don't need that much. And looking at your FT4 and FT3 numbers, I'm guessing you could drop your dose down a bit. Tiredness can certainly be a symptom of too much thyroid hormone for me.
That is sage advice. I don’t struggle with taking it all at once but I hear you re over medicated. I will try 3.5 grains in the morning and see if that works better
Don’t seem to. Some say you need a lot of t3 in one go to get the benefit DippyDame and taking it two doses don’t do it. You can but try and see if it helps . The peak can be a lot longer to happen in some people maybe 8-12 hours
I don’t notice any peak whatsoever, it all feels very smooth, pretty normal in fact I take 1.25 grains a day
So do I (feels smooth). I had terrible peaks on T3 and didn’t get on with it. The only problem with taking my NDT in the morning that persists is the afternoon slump. But still a lot better than on Levo, T3, combo or splitting NDT 😂
I split my Thyro-Gold bovine desiccated thyroid into two doses, 1 hour before and 4 hours after food as follows: Wake & take Thyro-Gold
After 1 hour eat breakfast
11:30‐12 eat dinner
4pm take Thyro-Gold
5pm or later eat
I personally would take 2 grains in the morning and 1.75 grains between 12-4pm.
By splitting your NDT dose, you get a boost from the T3 in each dose. By taking the second dose at lunch (remember to do an hour before eating), you should avoid the energy dip in the afternoon as it takes the T3, 2-4 hours to peak. I'm now on T3-only and get some benefit within 30 minutes of taking a dose.
It would be useful to know how long after taking your last NDT dose your blood test was done.
I have no thyroid and have been taking NDTs for about 8/9 years now. At first I took it all in one go AM. But for the past seven years have split the dose. I take 1.25 at 6am and the other one at around 1pm one hour after lunch. This works well for me with no thyroid. I don't have any other things stopping it i.e. age allergies etc.
Your levels seem good to me but I always feel well when my FT3 is higher above 6.
I split mine - 1.25 on waking and then 1.25 usually an hour after lunch (or an hour before if I'm late eating lunch). I still get a slump in the afternoon but it's not as bad as when I was on Levothyroxine.
The other day I read on a post on here about the optimum time to take supplements that Vitamin B (not sure if this was B12 or B complex) can prevent you sleeping so it's better to take it in the morning. Someone suggested taking Vit B in the afternoon to give you a boost if you get a slump. I've tried taking vitamin B a bit later a couple of times and I think it might help but it's quite hard to fit it in so that it can be far enough away from the NDT.
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