How much time between split NDT doses ? - Thyroid UK

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How much time between split NDT doses ?

Val-55 profile image
8 Replies

How much time should be between split NDT doses ? I take first dose at 7 and wait an hour before eating drinking . I'm finding that I don't take the second dose till nearly 3 , is that too late .? Thanks

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Val-55
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8 Replies
Clutter profile image
Clutter

Val-55,

Whatever suits you is fine. If it were me I'd take the first dose on waking and the second before bedtime, the same way as I take T4+T3.

Val-55 profile image
Val-55 in reply toClutter

Ah ok , would be easier than trying to find a window between food drink etc . Does it not keep you awake ?

Clutter profile image
Clutter in reply toVal-55

Val-55,

No. It helps some people sleep but will disrupt sleep in others. I'm not suggesting you change what is working for you but if 3pm interferes with drinks/food you can certainly shift the second dose to later.

Val-55 profile image
Val-55 in reply toClutter

I don't sleep well so it might be worth a try .. Thankyou

HarryE profile image
HarryE

I don't believe that eating or drinking affects NDT in the same way it does Levo. I have never avoided it.

Clutter profile image
Clutter in reply toHarryE

HarryE,

The T4 and T3 in NDT, Liothyronine and Levothyroxine bind with proteins in food which reduces absorption. If you've always taken NDT with food you will probably need to reduce dose if you change that.

TupennyRush profile image
TupennyRush

Hi there

I have the same regimen (7 am first dose and second 3-5 ish). I think everyone is a bit different so try various times and see what suits.

I started out taking a single dose at 7 am and noticed I flagged around 6 ish. The'top up' afternoon dose seems to sort it out

Val-55 profile image
Val-55

Yes Thankyou , I'm trying a t time dose now . See how it goes ,!

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