tiromel

[Gilbert2023]

anyone taking this version of t3 ?

I was on 100mg of levo and my Tsh lowered to 0.38 but my symptoms continue ,

If I take tiromel what dose should I start with ? Should I lower my levo ?

[TiggerMe Ambassador]

What is your current fT4 result?

When adding T3 start as small as your tablets allow so if you can cut into 8ths and take 1 with your T4 dose and wait at least 2 weeks to see how that settles, adding too much too soon can really mess people up and miss their sweet spot

It is fast acting but it takes your body months to re-adjust

[Gilbert2023 in reply to TiggerMe]

is ft4 free thyroxine? If so my test in august it was 25.8 ( medichecks )

[TiggerMe Ambassador in reply to Gilbert2023]

Yes, so you are above range (12-22) Was this 24 hours after last dose? What was your fT3?

You don’t want to change two things at once and adding T3 will likely lower your fT4.

When you recheck in 8weeks you might need to adjust then

[Gilbert2023 in reply to TiggerMe]

T3 was 4 at that time , would you stick to 100 levo though for now as my result for free thyroxine was high ?

[Gilbert2023 in reply to Gilbert2023]

My levothyroxine is 100 micro-grams daily ( I didn’t take it on my test day til after )

My inflammation CRP HS is 1.39

Ferritin is 275ug/L ( a bit high I think )

FOLATE 20.1nmol/L

Vitamin B12 active 64.9pmol/L

Vitamin D 78.8nmol/L

TSH 1.16 mIU/L

FREE T 3 4 pmol/L

FREE THYROXINE 25.8pmol/L

Results from medichecks ,

[TiggerMe Ambassador in reply to Gilbert2023]

I'd suggest sticking with 100mcg whilst you add T3 and reviewing in 8 weeks, you also need to improve your Vit D level, aiming for 100-150nmol/L grassrootshealth.net/projec...

Also your B12 would benefit by pushing to top of range 150pmol/L

You have a little general inflammation which could be why ferritin is a little raised, could also be raised if post menopausal?

[helvella Administrator]

If it is genuine Tiromel T3 then, whilst there has been some discussion over the years about whether it is slightly different in potency to other products, it is a perfectly decent product. Some members have used it for years.

However, there are all too many questionable suppliers who appear to be sending poor quality product. Whether it is an outright fake, out of date, or in some other way questionable.

📢 ⚠️ Purchasing thyroid (and other) medication without prescription - Please Be Wary! ⚠️ 📢 (Repost)

healthunlocked.com/thyroidu...

[sonia54]

When I was staring with T3 many years ago I first took 1/2 tablet. Most thyroid experts advised it should be done that way. Most tablets can be cut in 1/4 as well but it can never be done totally precisely even with the best pill cutter and on that way your daily dose will be uneven which is very important when you first start, not so much later. Cutting T3 pills in 1/8 is impossible without making crumbs.

[TiggerMe Ambassador in reply to sonia54]

Tiromel cuts quite well and tbh crumbs isn't a bad way to start to see how your body is going to react. Any pill splitting is going to be a bit hit and miss as the minuscule amount of T3 contained in a pill isn't going to be evenly spread

[SlowDragon Ambassador]

I would recommend you improve vitamin D, B12 levels FIRST before adding T3

Then retest

Exactly what vitamin supplements have you been taking

Which brand of levothyroxine are you taking do you always get same brand

You could try splitting Levo taking half at bedtime and half waking

This might increase TSH a little

[Sleepman]

I take tiromel and cut into quarters . I cut just now to 1/8 OK - not dust

I use a dedicated set of new/unused nail clippers to cutting them.

They are potent and fast acting.

I started on a 1/4 then a 1/2 that was too much in one go. My blood sugar dropped till I got used to it.

Then it was 1/4 x 2 times per day. Now take a 1/4 3 times per day.

My levo was 150 went to 100 in attempt to get TSH higher but not great at that. I am now on 125 mg. There is no magic formula.

It took a year and half to level things out as mostly well and no need to act too fast.

[SlowDragon Ambassador]

There’s nothing on your profile

is your hypothyroidism autoimmune?

What were TPO and TG antibodies

Have you had coeliac blood test

Hashimoto's affects the gut and leads to low stomach acid and then low vitamin levels

Low vitamin levels affect Thyroid hormone working

Poor gut function can lead leaky gut (literally holes in gut wall) this can cause food intolerances and IBS

Most common by far is gluten.

Dairy is second most common.

A trial of strictly gluten free diet is always worth doing

Only 5% of Hashimoto’s patients test positive for coeliac but a further 81% of Hashimoto’s patients who try gluten free diet find noticeable or significant improvement or find it’s essential

A strictly gluten free diet helps or is essential due to gluten intolerance (no test available) or due to leaky gut and gluten causing molecular mimicry (see Amy Myers link)

Changing to a strictly gluten free diet may help reduce symptoms, help gut heal and may slowly lower TPO antibodies

While still eating high gluten diet ask GP for coeliac blood test first as per NICE Guidelines

nice.org.uk/guidance/ng20/c...

Or buy a test online, about £20

Assuming test is negative you can immediately go on strictly gluten free diet 

(If test is positive you will need to remain on high gluten diet until endoscopy, maximum 6 weeks wait officially) 

Trying gluten free diet for 3-6 months. If no noticeable improvement then reintroduce gluten and see if symptoms get worse

chriskresser.com/the-gluten...

amymyersmd.com/2018/04/3-re...

thyroidpharmacist.com/artic...

drknews.com/changing-your-d...

Non Coeliac Gluten sensitivity (NCGS) and autoimmune disease

pubmed.ncbi.nlm.nih.gov/296...

The predominance of Hashimoto thyroiditis represents an interesting finding, since it has been indirectly confirmed by an Italian study, showing that autoimmune thyroid disease is a risk factor for the evolution towards NCGS in a group of patients with minimal duodenal inflammation. On these bases, an autoimmune stigma in NCGS is strongly supported

nuclmed.gr/wp/wp-content/up...

In summary, whereas it is not yet clear whether a gluten free diet can prevent autoimmune diseases, it is worth mentioning that HT patients with or without CD benefit from a diet low in gluten as far as the progression and the potential disease complications are concerned

restartmed.com/hashimotos-g...

Despite the fact that 5-10% of patients have Celiac disease, in my experience and in the experience of many other physicians, at least 80% + of patients with Hashimoto's who go gluten-free notice a reduction in their symptoms almost immediately.

Similarly few months later consider trying dairy free too.

Approx 50-60% find dairy free beneficial

With loads of vegan dairy alternatives these days it’s not as difficult as in the past

If you find dairy free helpful, change Levo to lactose free as well

Vencamil is best option for lactose free levothyroxine

Post discussing gluten

healthunlocked.com/thyroidu...

Recent research in China into food intolerances with Hashimoto’s

healthunlocked.com/thyroidu...

More interesting Chinese research on Hashimoto’s and leaky gut

nature.com/articles/s41598-...

[Gilbert2023]

all good info , I posted in my thread ‘ no improvements in a year ‘ showing I’m autoimmune and tests say not coeliac

[SlowDragon Ambassador in reply to Gilbert2023]

Only 5% of Hashimoto’s patients test positive for coeliac but a further 81% of Hashimoto’s patients who try gluten free diet find noticeable or significant improvement or find it’s essential

I would recommend trying it BEFORE T3

Do you always get same brand of levothyroxine

[Sleepman]

+1 for SlowDragon trying GF etc.

T3 needs more tests, more faff etc. - you also end up having issues with doctor as your TSH will likely be too low.

Have you got several blood tests showing very low T3 levels. I would only act after several.

I did not show on Celiac blood test but I cannot handle any without being tired and feeling pants for a week. We are not all the same though ... good luck