Update to the ongoing story

[Eccleston]

Hi,Following earlier posts I wrote to, and then consulted my GP, with a refusal to reduce Levothyroxine dosage until, what I perceive as being low fT3 is addressed. A referral to an NHS Endocrinologist has been made. Following this I have taken the advice received on this forum to supplement with the aim of optimising vitamin and iron levels. At the same time a DNA analysis specific to Thyroid has been carried out. The results are revealing!

Critical

DI01 - with a T allele on rs11206244

TSH Signalling - with an A allele on rs4704397

TSHR TSH Receptor - with an A allele on rs179247

TRHR TSH Receptor - with an G allele on rs3134105

The other main recommendation is that Selenium and Iodine levels should be optimal for best results.

Further, my analysis of my condition is that fT3 is not being cleared quickly enough, and may also be being over-produced in the T4 to T3 conversion process, leading to suppressed fT3 levels.

Next step will be to ask GP to advise Endo team of the results for them to come to a more informed decision as to future treatment.

Any comments and advice would be welcome.

Eccleston

[SlowDragon Administrator]

previous post shows significant vitamin deficiencies

Especially Active B12 and vitamin D

healthunlocked.com/thyroidu...

These need working on to improve to optimal for good conversion of Ft4 to Ft3

And 2 x 30mg propranolol will be significantly reducing uptake and conversion of Ft4 to Ft3

Discuss changing to different beta blocker

pubmed.ncbi.nlm.nih.gov/168...

rejuvagencenter.com/hypothy...

escardio.org/Journals/E-Jou...

labtestsonline.org.uk/tests...

Drugs that may decrease PTH include cimetidine and propranolol.

[Eccleston in reply to SlowDragon]

Hi, Apologies for not responding sooner.I have addressed the vitamin issues and am happy with the current situation. Propranolol was not even considered at recent consultation. If I can have sufficient T3 to counter its effects then ......

Eccleston

[SlowDragon Administrator in reply to Eccleston]

what are your most recent vitamin D, folate, B12 and ferritin

What vitamin supplements are you taking

Propranolol was not even considered at recent consultation. If I can have sufficient T3 to counter its effects the

That’s the wrong way to go about it

Other beta blockers don’t affect thyroid hormone levels

Request changing to different beta blocker

I saw 6 different thyroid specialists, not one of them seriously considered why and what effect propranolol was having 🤷‍♀️