Recent Blood Results: Hi All, I have just got my... - Thyroid UK

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Recent Blood Results

3mmarose profile image
18 Replies

Hi All,

I have just got my blood results back and I am wanting to know what you all think and if you have any suggestions on how to improve. I don't understand my antibodies results and why my LDL is so high.

Active B12 - 39 pmol/L (Normal Range 38 - 188)

Corrected Calcium - 2.18 mmol/L (Normal Range 2.05 - 2.55)

HDL - 1.91 mmol/L (Normal Range 1.16 - 1.68)

LDL - 3.5 mmol/L (Normal Range 0 - 3)

Total Cholesterol 5.8 mmol/L (Normal Range 0 - 5)

Triglycerides 0.93 mmol/L (Normal Range 0.84 - 1.94)

Thyroglobulin Antibodies - 297 IU/mL (Normal Range 0 - 115)

Thyroid Peroxidase Antibodies - 90 IU/mL (Normal Range 0 - 34)

TSH - 1.23 mIU/L (Normal Range 0.27 - 4.2)

T4 - 20.1 pmol/L (Normal Range 12 - 22)

T3 - 4.5 pmol/L (Normal Range 3.1 - 6.8)

Thank you x

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18 Replies
SlowDragon profile image
SlowDragonAdministrator

Your B12 is EXTREMELY low

Active B12 below 70 is considered suspect

Are you vegetarian or vegan

Request GP test B12 and folate together and full test for Pernicious Anaemia BEFORE considering starting any B vitamins

No ferritin or vitamin D test results?

3mmarose profile image
3mmarose in reply toSlowDragon

Thank you. My Vitamin D is low. I got it tested a few months ago and it was very low so I didn't retest it this time but will do next month.

For Ferritin, I had requested this to be checked but the provider, Forth, told me that they were unable to get a reading as the sample took too long to deliver which I thought was strange.

I am not a Vegetarian or Vegan. I eat chicken and fish maybe once or twice a week.

3mmarose profile image
3mmarose in reply to3mmarose

Also do you think the LDL is worrying or is this normal for those with hypothyroidism?

greygoose profile image
greygoose in reply to3mmarose

Also do you think the LDL is worrying or is this normal for those with hypothyroidism?

No. It isn't. High cholesterol levels are never anything to worry about. It's a symptom, not a disease. And yours is only very slightly high, anyway. And that's because of your low FT3.

High cholesterol does not cause heart attacks or strokes, as doctors would have you believe - because they want to prescribe statins. It's low cholesterol that is more likely to do that. And no-one has yet figured out a way to raise cholesterol if it's naturally too low. So, forget cholesterol and concentrate on raising your FT3 and your other nutrients. :)

3mmarose profile image
3mmarose in reply togreygoose

Thank you for this. How do I increase my FT3?

greygoose profile image
greygoose in reply to3mmarose

Good question. Well, T4 (levo) is supposed to convert to T3. But, judging by your blood test results, you are a poor converter. The could be due to low nutrient levels, so first step is to optimise those. But it could also be due to many other things over which you have no control.

So, if optimising nutrients doesn't help, then the other option is to obtain T3 and take that along side your levo. This can be problematic because it's very hard to get it on the NHS. And you would have to see and endo and 'prove' you need it. But, if that fails, you could buy your own on-line without a prescription. Many of us do that. :)

3mmarose profile image
3mmarose in reply togreygoose

Thank you!

I will start with my vitamins and failing that, will look at T3. When would you recommend re-testing vitamin levels?

Also, is there a brand of T3 that you would recommend? :)

Thanks again

greygoose profile image
greygoose in reply to3mmarose

Some nutrient levels can take a long time to raise - iron and vit D especially. With B vits it's quicker. But, I would leave at least six weeks, like for thyroid.

With T3 I'm afraid you have to take what you can get. You rarely get a choice. But, I've tried most of them and find them much of a muchness. Although I did find it difficult to get the right dose with Thybon Henning. In any case, we're all different and have to find what suits us as an individual, never mind what suits everyone else. :)

SlowDragon profile image
SlowDragonAdministrator in reply to3mmarose

Request GP test full iron panel including ferritin

Your conversion of Ft4 (levothyroxine) to Ft3 (active hormone) is currently very poor

Improving low vitamin levels essential to improve poor conversion

Low Ft3 tends to result in vitamin levels dropping further

Low Ft3 will also result in higher cholesterol

nhs.uk/conditions/statins/c...

If you have an underactive thyroid (hypothyroidism), treatment may be delayed until this problem is treated. This is because having an underactive thyroid can lead to an increased cholesterol level, and treating hypothyroidism may cause your cholesterol level to decrease, without the need for statins. Statins are also more likely to cause muscle damage in people with an underactive thyroid.

3mmarose profile image
3mmarose in reply toSlowDragon

Thank you. I prefer to have finger prick tests instead of in arm blood tests like at the GP. I had my Ferritin levels last checked in December 2023 and they were low, I went to the GP about it and they did a full panel and told me I was fine.

Feritin Level was 27 ug/l (Normal range 30-150)

Folate was 9.6 nmol (Normal range 8.83 - 60.8)

Might need a new GP!

SlowDragon profile image
SlowDragonAdministrator in reply to3mmarose

GP needs to go to Specsavers

So what are you doing about low ferritin

cks.nice.org.uk/topics/anae...

Serum ferritin level is the biochemical test, which most reliably correlates with relative total body iron stores. In all people, a serum ferritin level of less than 30 micrograms/L confirms the diagnosis of iron deficiency.

Never supplement iron without doing full iron panel test for anaemia first and retest 3-4 times a year if self supplementing.

It’s possible to have low ferritin but high iron

Test early morning, only water to drink between waking and test. Avoid high iron rich dinner night before test

Medichecks iron panel test

medichecks.com/products/iro...

Look at increasing iron rich foods in diet

Eating iron rich foods like liver or liver pate once a week plus other red meat, pumpkin seeds and dark chocolate, plus daily orange juice or other vitamin C rich drink can help improve iron absorption

List of iron rich foods

dailyiron.net

Links about iron and ferritin

irondisorders.org/too-littl...

davidg170.sg-host.com/wp-co...

Great in-depth article on low ferritin

oatext.com/iron-deficiency-...

drhedberg.com/ferritin-hypo...

This is interesting because I have noticed that many patients with Hashimoto’s disease and hypothyroidism, start to feel worse when their ferritin drops below 80 and usually there is hair loss when it drops below 50.

healthunlocked.com/thyroidu...

Posts discussing Three Arrows as very effective supplement

Great replies from @FallingInReverse

re ferritin and Three arrows

healthunlocked.com/thyroidu......

healthunlocked.com/thyroidu...

healthunlocked.com/thyroidu...

Iron patches

healthunlocked.com/thyroidu...

Thyroid disease is as much about optimising vitamins as thyroid hormones

healthunlocked.com/thyroidu...

restartmed.com/hypothyroidi...

Post discussing just how long it can take to raise low ferritin

healthunlocked.com/thyroidu...

Iron and thyroid link

healthunlocked.com/thyroidu...

Posts discussing why important to do full iron panel test

healthunlocked.com/thyroidu...

Good iron but low ferritin

healthunlocked.com/thyroidu...

healthunlocked.com/thyroidu...

Chicken livers if iron is good, but ferritin low

healthunlocked.com/thyroidu...

Shellfish and Mussels are excellent source of iron

healthline.com/nutrition/he...

Iron deficiency without anaemia

healthunlocked.com/thyroidu...

Ferritin over 100 to alleviate symptoms

healthunlocked.com/thyroidu...

healthunlocked.com/thyroidu...

Great research article discussing similar…..ferritin over 100 often necessary

ncbi.nlm.nih.gov/pmc/articl...

Low Iron implicated in hypothyroidism

healthunlocked.com/thyroidu...

Really interesting talk on YouTube, link in reply by Humanbean discussing both iron deficiency and towards end how inflammation can also be an issue

healthunlocked.com/thyroidu...

Inflammation affecting ferritin

healthunlocked.com/thyroidu...

Updated reference ranges for top of ferritin range depending upon age

healthunlocked.com/thyroidu...

Thank you for your incredible patience while you have been awaiting the outcome of our ferritin reference range review. We conducted this with Inuvi lab, which has now changed the reference ranges to the following:

Females 18 ≤ age < 40. 30 to 180

Females 40 ≤ age < 50. 30 to 207

Females 50 ≤ age < 60. 30 to 264l

Females Age ≥ 60. 30 to 332

Males 18 ≤ age < 40 30 to 442

Males Age ≥ 40 30 to 518

The lower limits of 30 are by the NICE threshold of <30 for iron deficiency. Our review of Medichecks data has determined the upper limits. This retrospective study used a large dataset of blood test results from 25,425 healthy participants aged 18 to 97 over seven years. This is the most extensive study on ferritin reference ranges, and we hope to achieve journal publication so that these ranges can be applied more widely.

SlowDragon profile image
SlowDragonAdministrator in reply to3mmarose

Folate was 9.6 nmol (Normal range 8.83 - 60.8)

What was B12 at GP test ?

Note that improving folate when B12 is very low is not a good idea. Taking folate before B12 is good enough can lead to severe neurological problems.

en.wikipedia.org/wiki/Subac...

It is vital if you intend to supplement both B12 and folate that B12 is started a week before the folate.

If GP is unhelpful you could consider private B12 injections

Low B12 symptoms

b12deficiency.info/signs-an...

methyl-life.com/blogs/defic...

With serum B12 result below 500, (Or active B12 below 70) recommended to be taking a separate B12 supplement

A week later add a separate vitamin B Complex 

Then once your serum B12 is over 500 (or Active B12 level has reached 70), you may be able to reduce then stop the B12 and just carry on with the B Complex.

If Vegetarian or vegan likely to need ongoing separate B12 few times a week

Highly effective B12 drops

natureprovides.com/products...

Or

B12 sublingual lozenges

uk.iherb.com/pr/jarrow-form...

cytoplan.co.uk/shop-by-prod...

B12 range in U.K. is too wide

Interesting that in this research B12 below 400 is considered inadequate

healthunlocked.com/thyroidu...

Low folate

supplementing a good quality daily vitamin B complex, one with folate in (not folic acid)

This can help keep all B vitamins in balance and will help improve B12 levels too

Difference between folate and folic acid

healthline.com/nutrition/fo...

Many Hashimoto’s patients have MTHFR gene variation and can have trouble processing folic acid supplements

thyroidpharmacist.com/artic...

B vitamins best taken after breakfast

Igennus B complex popular option. Nice small tablets. Most people only find they need one per day. But a few people find it’s not high enough dose

Post discussing different B complex

healthunlocked.com/thyroidu...

Thorne Basic B recommended vitamin B complex that contains folate, but they are large capsules. (You can tip powder out if can’t swallow capsule) Thorne can be difficult to find at reasonable price, should be around £20-£25. iherb.com often have in stock. Or try ebay

IMPORTANT......If you are taking vitamin B complex, or any supplements containing biotin, remember to stop these 7 days before ALL BLOOD TESTS , as biotin can falsely affect test results

endo.confex.com/endo/2016en...

endocrinenews.endocrine.org...

In week before blood test, when you stop vitamin B complex, you might want to consider taking a separate folate supplement (eg Jarrow methyl folate 400mcg) and continue separate B12

Post discussing how biotin can affect test results

healthunlocked.com/thyroidu...

helvella.blogspot.com/p/hel...

Post discussing start B12 injections

healthunlocked.com/thyroidu...

SlowDragon profile image
SlowDragonAdministrator in reply to3mmarose

My Vitamin D is low. I got it tested a few months ago and it was very low so I didn't retest it this time but will do next month.

How low was vitamin D. How much vitamin D are you taking

3mmarose profile image
3mmarose in reply toSlowDragon

It was 45 nmol/l (Normal range 50-250)

3mmarose profile image
3mmarose in reply to3mmarose

I am taking 1000IU Vitamind D Spray

SlowDragon profile image
SlowDragonAdministrator in reply to3mmarose

Quite likely not high enough dose

GP should prescribe 1600iu everyday for 6 months

NHS Guidelines on dose vitamin D required says at least 1600iu daily

ouh.nhs.uk/osteoporosis/use...

GP will often only prescribe to bring vitamin D levels to 50nmol.

Some areas will prescribe to bring levels to 75nmol or even 80nmol

leedsformulary.nhs.uk/docs/...

GP should advise on self supplementing if over 50nmol, but under 75nmol (but they rarely do)

mm.wirral.nhs.uk/document_u...

But with Thyroid issues, improving to around 80nmol or 100nmol by self supplementing may be better

pubmed.ncbi.nlm.nih.gov/218...

vitamindsociety.org/pdf/Vit...

Once you Improve level, very likely you will need on going maintenance dose to keep it there.

Test twice yearly when supplementing

Can test via NHS private testing service

vitamindtest.org.uk

Vitamin D mouth spray by Better You is very effective as it avoids poor gut function.

There’s a version made that also contains vitamin K2 Mk7.

One spray = 1000iu

amazon.co.uk/BetterYou-Dlux...

It’s trial and error what dose we need, with thyroid issues we frequently need higher dose than average

Vitamin D and thyroid disease

grassrootshealth.net/blog/t...

Vitamin D may prevent Autoimmune disease

newscientist.com/article/23...

Web links about taking important cofactors - magnesium and Vit K2-MK7

Magnesium best taken in the afternoon or evening, but must be four hours away from levothyroxine

betterbones.com/bone-nutrit...

medicalnewstoday.com/articl...

livescience.com/61866-magne...

sciencedaily.com/releases/2...

Interesting article by Dr Malcolm Kendrick on magnesium

drmalcolmkendrick.org/categ...

Vitamin K2 mk7

betterbones.com/bone-nutrit...

healthline.com/nutrition/vi...

Too much Vitamin D is toxic

Test twice a year

healthunlocked.com/thyroidu...

Rosills1 profile image
Rosills1

Have you considered gluten sensitivity?

3mmarose profile image
3mmarose in reply toRosills1

I don’t eat a lot of gluten and I did try gluten free along with a dairy free diet a few months back and didn’t really see much of a difference to be honest but do you think a gluten sensitivity would have an effect on my nutrient levels? If so, I would definitely try going off it again!

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