Help understanding coeliac test results - Thyroid UK

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Help understanding coeliac test results

Feelingrubbish profile image
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Recent results of testing for coeliac. Doctor says 'no further action'.

Tissue transglutaminase IgA level 0.3 U/mL [0.0 - 10.9]

Immunoglobulin A level 2.06 g/L [0.8 - 4.0]

Should I be concerned that the first result is very low in the range?

My ferritin and iron were tested at the same time (again noted with 'no further action').

Serum ferritin level 31 ug/L [30.0 - 250.0] was 26 @ 30/8/22

Serum iron level 21 umol/L [9.0 - 30.0] was 15 @ 30/8/22

Serum transferrin level 2.77 g/L [1.8 - 3.82]

Transferrin saturation index 29 % [15.0 - 50.0] was 23% @ 30/8/22

I have been working on increasing my ferritin and iron by eating liver, liver pate and red meat regularly and I also daily supplement Solgar Gentle Iron 20mg with Solgar Vit C 500mg. I am trying to improve my hair loss.

Should I increase the amount of supplements?

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SlowDragon profile image
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Coeliac blood test is negative

So you can now trial absolutely strictly gluten free diet for 3-6 months

Likely to see benefit, it’s ALWAYS worth trying

Hashimoto's affects the gut and leads to low stomach acid and then low vitamin levels 

Low vitamin levels affect Thyroid hormone working 

Poor gut function can lead leaky gut (literally holes in gut wall) this can cause food intolerances. Most common by far is gluten. Dairy is second most common. 

According to Izabella Wentz the Thyroid Pharmacist approx 5% with Hashimoto's are coeliac, but over 80% find gluten free diet helps, sometimes significantly. Either due to direct gluten intolerance (no test available) or due to leaky gut and gluten causing molecular mimicry (see Amy Myers link) 

Changing to a strictly gluten free diet may help reduce symptoms, help gut heal and slowly lower TPO antibodies 

Trying gluten free diet for 3-6 months.

If no noticeable improvement then reintroduce gluten and see if symptoms get worse

chriskresser.com/the-gluten...

amymyersmd.com/2018/04/3-re...

thyroidpharmacist.com/artic...

drknews.com/changing-your-d...

Non Coeliac Gluten sensitivity (NCGS) and autoimmune disease

pubmed.ncbi.nlm.nih.gov/296...

The predominance of Hashimoto thyroiditis represents an interesting finding, since it has been indirectly confirmed by an Italian study, showing that autoimmune thyroid disease is a risk factor for the evolution towards NCGS in a group of patients with minimal duodenal inflammation. On these bases, an autoimmune stigma in NCGS is strongly supported

nuclmed.gr/wp/wp-content/up...

In summary, whereas it is not yet clear whether a gluten free diet can prevent autoimmune diseases, it is worth mentioning that HT patients with or without CD benefit from a diet low in gluten as far as the progression and the potential disease complications are concerned

restartmed.com/hashimotos-g...

Despite the fact that 5-10% of patients have Celiac disease, in my experience and in the experience of many other physicians, at least 80% + of patients with Hashimoto's who go gluten-free notice a reduction in their symptoms almost immediately.

Similarly in say 6 months after trialing gluten free, worth trying dairy free

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