Hi, I have an 18 year old daughter who is suffering from chronic fatigue (amongst other symptoms such as very low immunity, acne and awful constipation/stomach problems, hair loss and elevated LDL cholesterol). She's currently so ill that she's had to withdraw from her A levels and sadly won't be able to start Uni in the Autumn which is devastating for her.
I've posted some previous blood tests results about a month ago (from Medichecks) and I received some very helpful advice about a possible diagnosis of central hypothyroidism. Since then we've had more blood tests carried out and she has also been seen by an endo. Her most recent blood tests are as follows:
TSH - 1.54 (carried out at 4.30pm)
FT3 - 3.4 (3.1-6.8), her level was then tested a week later and it was exactly the same!
FT4 - 12.7 (12 - 22)
Thyroid antibodies tested previously and all normal
Vitamin D - 119 (50 - 200)
Ferritin - 75 (13-150)
Active B12 - 150 (37.5 - 150)
Folate - 12.23 (no range given)
9am Cortisol - 242
Short Synatchen test - base level 170 (at 11.15am) increased to over 600 an hour later. ACTH - still waiting for this result, but endo says it will be fine as she passed the SST with flying colours.
IGF1 - 37.9
All female hormones were in range when tested although she does have very irregular periods.
We assumed that her endo would diagnose her with central hypothyroidism, however all she's really said so far is that her thyroid hormones look a bit sluggish. As her females hormones and IGF-1 have come back as normal she doesn't think she has hypopituitarism but she seems very unwilling to offer any other suggestions as to what else might be causing her chronic fatigue and other problems. Her letter to our GP stated "this young lady is convinced that her problems are related to low thyroid levels"!!
She has been willing to give my daughter a trial of Levothyroxine, with 25 grs as a starting dose, but has advised us that if it doesn't work we would be able to rule out a problem with her thyroid. We are pretty sure that many of my daughters problems are caused by low thyroid levels - her vitamin levels are very healthy and she also has a pretty good diet, so I don't really know where we go from here if our endo advises us that her chronic fatigue isn't caused by hypothyroidism. We're very concerned that she might end up with a diagnosis of CFS which would mean that no one would have to provide her with any further help!
I'd would love to know whether anyone has any thoughts on these results and where we might go from here. We're aware that her 9am cortisol result was pretty low (242) but as she passed the SST, our endo doesn't think it's an issue.
Many thanks for your help.