Cortisol results + Hashimotos : Hello! Hoping... - Thyroid UK

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Cortisol results + Hashimotos

Mfjames profile image
4 Replies

Hello! Hoping someone can help me understand high cortisol results and possible next steps, alongside thyroid results from a Blue Horizon blood test - thanks!

For context I was diagnosed with Hashimotos 5 months ago and am currently on 50 mg Levo , but feeling unwell, fatigued, joint point - so decided to do a private test to see if any other underlying issues at hand:

Cortisol hormone (blood test)

562 at 8 am (Range for 6am - 10 am 113-456)

- 24 hour saliva test recommended

Magnesium 1.09

(Range 0.7-1.0)

Vitamin D 59

(Range 50-175)

Serum folate 16.6

(Range 8.83- 60.8)

antibody TPO - 309

( range < 34)

TSH 3.91 - on 50mg Levo

(Range 0.27-4.20)

Hoping to increase to 75 in new year but need to get blood test with GP before this

T4 and T3 in middle of UK normal ranges, as was B12 results so seemed ok.

Thanks :)

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SlowDragon profile image
SlowDragonAdministrator

High cortisol is common when hypothyroid as adrenals try to compensate for lack of thyroid hormones

Please add actual B12 result too

Vitamin D 59

(Range 50-175)

Vitamin D is too low

Are you currently taking any vitamin supplements ?

GP will often only prescribe to bring levels to 50nmol.

Some areas will prescribe to bring levels to 75nmol or even 80nmol

leedsformulary.nhs.uk/docs/...

GP should advise on self supplementing if over 50nmol, but under 75nmol (but they rarely do)

mm.wirral.nhs.uk/document_u...

NHS Guidelines on dose vitamin D required

ouh.nhs.uk/osteoporosis/use...

But with Hashimoto’s, improving to around 80nmol or 100nmol by self supplementing may be better

ncbi.nlm.nih.gov/pubmed/218...

vitamindsociety.org/pdf/Vit...

Once you Improve level, very likely you will need on going maintenance dose to keep it there.

Test twice yearly via vitamindtest.org.uk

Vitamin D mouth spray by Better You is very effective as it avoids poor gut function. There’s a version made that also contains vitamin K2 Mk7

amazon.co.uk/BetterYou-Dlux...

It’s trial and error what dose we need, with hashimoto’s we frequently need higher dose than average

Calculator for working out dose you may need to bring level to 40ng/ml = 100nmol

grassrootshealth.net/projec...

Government recommends everyone supplement October to April

gov.uk/government/news/phe-...

Taking too much vitamin D is not a good idea

chriskresser.com/vitamin-d-...

Web links about taking important cofactors - magnesium and Vit K2-MK7

Magnesium best taken in the afternoon or evening, but must be four hours away from levothyroxine

betterbones.com/bone-nutrit...

medicalnewstoday.com/articl...

livescience.com/61866-magne...

sciencedaily.com/releases/2...

Vitamin K2 mk7

betterbones.com/bone-nutrit...

healthline.com/nutrition/vi...

SlowDragon profile image
SlowDragonAdministrator

antibody TPO - 309

( range < 34)

This confirms autoimmune thyroid disease aka Hashimoto’s

Hashimoto's frequently affects the gut and leads to low stomach acid and then low vitamin levels

Low vitamin levels affect Thyroid hormone working

Poor gut function can lead leaky gut (literally holes in gut wall) this can cause food intolerances. Most common by far is gluten. Dairy is second most common.

According to Izabella Wentz the Thyroid Pharmacist approx 5% with Hashimoto's are coeliac, but over 80% find gluten free diet helps, sometimes significantly. Either due to direct gluten intolerance (no test available) or due to leaky gut and gluten causing molecular mimicry (see Amy Myers link)

Changing to a strictly gluten free diet may help reduce symptoms, help gut heal and slowly lower TPO antibodies

While still eating high gluten diet ask GP for coeliac blood test first or buy test online for under £20, just to rule it out first

healthcheckshop.co.uk/store...?

Assuming test is negative you can immediately go on strictly gluten free diet

(If test is positive you will need to remain on high gluten diet until endoscopy, maximum 6 weeks wait officially)

Trying gluten free diet for 3-6 months. If no noticeable improvement then reintroduce gluten and see if symptoms get worse

chriskresser.com/the-gluten...

amymyersmd.com/2018/04/3-re...

thyroidpharmacist.com/artic...

drknews.com/changing-your-d...

restartmed.com/hashimotos-g...

Non Coeliac Gluten sensitivity (NCGS) and autoimmune disease

ncbi.nlm.nih.gov/pubmed/296...

The predominance of Hashimoto thyroiditis represents an interesting finding, since it has been indirectly confirmed by an Italian study, showing that autoimmune thyroid disease is a risk factor for the evolution towards NCGS in a group of patients with minimal duodenal inflammation. On these bases, an autoimmune stigma in NCGS is strongly supported

ncbi.nlm.nih.gov/pubmed/300...

The obtained results suggest that the gluten-free diet may bring clinical benefits to women with autoimmune thyroid disease

nuclmed.gr/wp/wp-content/up...

In summary, whereas it is not yet clear whether a gluten free diet can prevent autoimmune diseases, it is worth mentioning that HT patients with or without CD benefit from a diet low in gluten as far as the progression and the potential disease complications are concerned

restartmed.com/hashimotos-g...

Despite the fact that 5-10% of patients have Celiac disease, in my experience and in the experience of many other physicians, at least 80% + of patients with Hashimoto's who go gluten-free notice a reduction in their symptoms almost immediately.

SlowDragon profile image
SlowDragonAdministrator

What were TSH, Ft4 and Ft3 results?

Mfjames profile image
Mfjames

Hi SlowDragon - thanks so much for your quick and helpful responses !

I’ll make sure I add full test results here, I wasn’t sure if they were needed as apparently in the ‘normal’ range :)

Also I should have added I’m a woman in my thirties and recently had a negative test for coeliac disease which is in my family.

Vitamin B12 - 356

(Range 145-569)

Ferritin - 96.8

(Range 13-150)

T4 total - 91

(66-181)

Free T4 - 16.9

(12-22)

Free T3 - 5.04

(3.01-6.8)

I realise I also didn’t add my anti thyroglobulin antibodies which are at : 100

(Range <115)

Thank you!

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