Metavive dosage: Hi all, Hope you are doing ok... - Thyroid UK

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Metavive dosage

CBann profile image
9 Replies

Hi all,

Hope you are doing ok.

I just wondered if anyone could provide some advice on swapping from T4 and T3 synthetic to metavive. In terms of how I move over and by how much. I have metavive in the post. I am not sure I’m comfortable with dropping the synthetics completely and starting at 1 dose of metavive 1.

Bit of background. I was happily dosing 3.5 grains of nature throid before it went south. I only noticed the change in around feb this year. At that point I decided to switch to the synthetic combo but unfortunately it doesn’t seem to work for me. I mean it works to a certain extent - my blood work looks fine (T4 top third of range and T3 top) but I’m still left with symptoms, the worst offender being hair loss, as well as low mood, spots and getting cold to my bones. I am currently taking 75 T4 and 62.5 T3 (T3 is dosed through the day)

I’ve done all vitamin tests and they come up fine (top of range or slightly above) , apart from I don’t think I have had my folate tested.

I have tried decreasing T4, ignoring bloods and adding more T3. Going T3 only which I only managed for 4 days - I woke every night with really bad body aches. Result was about 4hrs sleep. I’m a working mum to a 2 year old so would not survive living off 4 hrs sleep.

My gut tells me that there is something in the synthetic T4 that is not agreeing with me or that there was something in the NDT that I need to make everything work. Possibly I just need all the hormones (inc. t1 and 2) in the right natural balance to feel well.

Anyway any support would be massively appreciated. If metavive does not work my next move would be to try armour but the cost is quite high for a trail and there are so many mixed reviews

Sorry for the long boring post.

X

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CBann
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9 Replies
Canu profile image
Canu

Hi CBann. I've just switched from NDT to Metavive but Im still new to all this myself. From what I understand, theoretically, Metavive I is supposed to be equivalent to 1/4 grain NDT and Metavive II to 1/2 grain NDT. But, from reading some posts on here where people shared their experiences when switching from NDT to Metavive, it looks like many had overmedication symptoms. As Metavive seems to be more potent for some people, if I were you, I would start with 3 Metavive II and build up as needed.

(And test your folate.) :)

CBann profile image
CBann in reply to Canu

Hi Canu

Thanks so much for your reply. That’s really helpful. What brand of NDT are you switching from? And how have things gone so far for you with metavive? I wish I had this information before I ordered, I’ve only got one bottle of metavive 1. Nevermind I’ll start with 6 and see where that gets me. Does feel quite scary tho as the amount of T3 I’d be getting is so low in comparison to now. 🤔

Do you split the dose of metavive? And do you track your temperature?

Sorry so many questions.

I’ll request a folate test from the GP’s on Monday. Thanks 😊

Canu profile image
Canu in reply to CBann

Hi! I was on Armour before switching to Metavive. I only switched 3 days ago, so I can't say much about it yet. Yes, I split the dose - half in the morning and half at 3pm (even though I didn't when I was on Armour). I think there's more to it than just how much T4 and how much T3 is in it. Apparently, there are other helpful things in whole desiccated thyroid that NDT doesn't have, though I don't remember what exactly. But you may need to increase at some point.

Yes, tracking your basal temperature is a good idea. I usually forget to do that as soon as I wake up, and I remember after I've moved about too much.

CBann profile image
CBann in reply to Canu

Hi. So armour didn’t work for you then? I got my metavive in the post today. Thermometer on the way. I’m going to give it a go tomorrow. Fingers crossed it works for us 🤞

Canu profile image
Canu in reply to CBann

I've generally been having a lot of trouble balancing my thyroid, but I've also been wanting to try Metavive because it's more natural and pure than Armour, as well as much cheaper and no need to get a prescription for it.

Fingers crossed!!!

reliablerebel profile image
reliablerebel

Hi there, I have moved from ndt (thiroyd) to metavive. Was taking 3 thiroyd/day, now taking 2 metavive11/day. Did try to take 3 metavive11/day but ended up overmedicated. Recent blood tests are good, could probably try raising a little with adding in one metavive1/day, and have ordered some. But I feel great, no symptoms, so if adding a little extra causes overmedication again, I will be quite happy to stay on current dose. Metavive is definitely stronger than most people realize, I am one of many who has managed to overmedicate on it initially. Good luck x

CBann profile image
CBann in reply to reliablerebel

Hiya. Thanks so much for the reply. It’s really good to know how people are getting on. Glad your doing well on it. Do you split the dose or just take it all in one go? X

reliablerebel profile image
reliablerebel in reply to CBann

No I don't split the dose, I probably should, but I work varied shifts, so take it at 7am either getting up or going to bed. I would get in a terrible muddle if I tried to split it and that would be worse.

CBann profile image
CBann in reply to reliablerebel

Ok thanks. I’m probably going to split it to start with as I have been doing with the synthetics, also to avoid taking too much in one go and judging how I feel.

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