Metavive III and IV bovine trial.

[Starsw]

Hello to you all.

After being on Thyroids S for years with some interruption because of shortage.I tried Metavive I and II good level of hormone in the blood there but thyroid inflammation probably because of the added nucleotides then a try Forefront my for ever supressed THS climb to 27 after 5 weeks and a very low level of hormone.

I felt a bit high on Thyroid S even when tweaking on the dosage usually taking 2.75 Thyroid S a day.

I decided to try Metavive bovine because the amount of nucleotides is really low respective to the content in porcine Metavive III has 32mg of dry gland with 8 mg of nucleotides added so sold as 40mg

Metavive IV has 65mg of dry gland and 15mg nucleotides added sold as 80mg.

So for 5 weeks I have taken one Metavive IV plus one metavive III in the morning and one Metavive III in the evening.

My test came back as:

THS: 0.01 (range 0.27-4.2 mU/L)

TF4: 18.1 (range 12-22 pmol/L)

FT3: 3.6 (range 3.1-6.8 pmol/L)

TP0 antibodies: 126IU/mL should be < to 35. too high but I have Hashimoto.

Yes I stopped biotin and my vitamin D level are good also take selenium 200 micrograms most of the time.

I also tested exactly 12 hours after my last dose of metavive.

I recently tested for the DIO2 rs225014 and i have got a CC so i have the double variant making me unlikely to convert T4 into T3 properly which I kind of expected after my very poor experience with levothyroxine. I have been on thyroid S (self medicating) for 10 years now.

Anyway my question is should i persevere with Bovine metavive and add 1 Metavive III which would go as 1 met IV plus one Met III in the morning and 1 Met IV in he evening and test again in 5 weeks to see if my FT3 are coming higher or should i go back to thyroid S as my FT4 were around 17.1 (same range) and my FT3 were at 7 (same range) slightly too high and feeling a bit shaky at time, any experience with bovine glandular welcome.

Thank you.

😊

[Angie33]

Hi, I'm sorry you are trying to get to the bottom of your thyroid too. Interesting for me to read about your experience on metavive Porcine, with the added nucleotides!

I used to be on metavive porcine, and it worked great. However, as I experienced heart fluctuations(for different reasons) I came off these so my GP could monitor me. I then switched to conventional medicine, which didn't work so returned to metavive after 2 years. This time metavive porcine didn't work! I was advised the only new ingredient was nucleotides and should have no affect on me at all. However, you felt it caused inflammation so changed to metavive bovine!! Very interesting!!

I am experimenting myself just now. I wish you all the best. This sure is a journey eh!

[Starsw in reply to Angie33]

Hi Angie

The problem with nucleotides is it depends on the dose there are 50 mg in 1 capsule of Metavive II so if you take 3 to 5 capsules it is all adding up there is only15 mg in the Metavive IV so hopefully even by taking 3 capsules let say it is less than in 1 capsule of metavive II. When I tried Metavive porcine my test were good but i got thyroiditis with violent headaches and thought it was triggering an anti=bodies attack as nucleotides seems to enhanced the immune system.

I wish we had more option with main stream medication. 😊

[Noelnoel in reply to Starsw]

Raising your dose by Met lll x 1 would likely have raised your FT4 and FT3 but the disparity between them might’ve increased if you’re correct in your assertion that you possibly have a conversion problem

I realise this is an old post but your experience may help inform other Metavive users, such as me

Thanks

[TiggerMe in reply to Noelnoel]

I hadn't realised quite how much higher the T3 ratio is in porcine as opposed to bovine so it would seem counter productive to switch to bovine when trying to raise fT3?

I'm only just learning about NDT

[Gingernut44]

I can’t comment on the bovine Metavive but, if you were feeling well on Thyroid S, why not go back on that but lower your dose slightly so that your FT3 doesn’t go above the reference range. It’s just such a trial trying to find the best solution.

[Starsw in reply to Gingernut44]

Thank you for your reply. I have heard that for many Bovine thyroid is better respective to sleep and spike of hyperactivity. even when my levels are good with Thyroid S i find that i suffer from insomnia, which seems better when taking bovine. I know on my results T3 are low (still in range) but this is 12 hours after taking 1/4 of my dose as I take 3/4 in the morning. I also wanted to find an alternative source in the UK.

I cannot increase my dose as my T4 would be over range but i could try 1/2 dose in the morning and 1/2 dose in the evening to balance it out. I could also mix Thyroid S and Metavive Bovine. just looking for answers to help with sleep and a slight elevated heart rate at rest when on Thyroid S which I think is caused by T3.

😊

[Angie33 in reply to Gingernut44]

thank you. Yeah decided to stay on my 40mg of T3 and introduce metavive I for 6 weeks’ to see how l feel. It’s been 2 weeks’ now snd today l managed a 20 min cycle plus chores! Good day!