Good afternoon. The past three weeks my heart rate has been really high (taking beta blockers as Resting heart rate is increased from 65 to 95). I’ve been advised to drop my levothyroxine from 100 down to to then 25. I was also advised to get a blood test... the results are below.
Should I be concerned that my TP0 antibodies have increased? I’m till feeling symptomatic ... fatigue, tired, shaky, and heart racing.
My T4 has increased a lot in the past month, it has been slow in the months before.
My tsh is suppressed and has dropped down again. Any advice gratefully received. I can’t seem to get any answers as to what’s happening to me!
Thanks!
TPO ANTIBODIES (range 0-5.60ku/L)
JAN 2020 - 150.8 POSITIVE
JULY 2020 - 39.6 POSITIVE
OCT 2020 - 231 POSITIVE
SERUM TSH (range 0.35-5.00mu/L)
JAN 2020 - 1.75
MAR 2020 - 1.51
APRIL 2020 - 0.66
JULY 2020 - 0.41
SEPT 2020 - 0.07
OCT 2020 - <0.01
SERUM FREE T4 (range 9.00-22.0pmol/L)
JAN 2020 - 9.7
MAR 2020 - 11.1
APRIL 2020 - 13.3
JULY 2020 - 11.7
SEPT 2020 - 13.6
OCT 2020 - 21
SERUM FREE T3 (range 2.40-6.00pmo/L)
MAY 2020 - 3.80
JULY 2020 - 4.6
FERRITIN (range 10.00-200.00)
AUG 2019 - 8
JAN 2020 - 50
MAR 2020 - 32
MAY 2020 - 23
JULY 2020 - 31
SEPT 2020 - 36
OCT 2020 - 42
VITAMIN B12 (range 200.00 - 910.00ng/L)
NOV 2019 - 840
JAN 202 - 705
MAY 2020 - 705
JULY 2020 - 869
SEPT 2020 - 1036 (OVER RANGE)
OCT 2020 - 880
SERUM FOLATE (range 3.00 - 20.00ug/L)
NOV 2019 - 8.4
JULY 2020 - 8.2
SEPT 2020 - 17.7
OCT 2020 - 19.7
VITAMIN D (range 50.00 - 200.00nmol/L)
JULY 2020 - 119
OCT 2020 - 118
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Flashgirl
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So high thyroid antibodies confirms autoimmune thyroid disease also called Hashimoto’s
Hashimoto’s, especially in early stages has temporary transient hyperthyroid flares.....where cells of thyroid break down releasing excess thyroid hormones
This may be what you are currently experiencing
High heart rate can also be due to low Ft3
July Ft3 was low
Poor conversion of Ft4 to Ft3 is common with Hashimoto’s
Recommended on here that all thyroid blood tests should ideally be done as early as possible in morning and before eating or drinking anything other than water .
Last dose of Levothyroxine 24 hours prior to blood test. (taking delayed dose immediately after blood draw).
This gives highest TSH, lowest FT4 and most consistent results. (Patient to patient tip)
Is this how you do your tests?
Private tests are available as NHS currently rarely tests Ft3 or thyroid antibodies or all relevant vitamins
Vitamin levels look pretty good ...apart from ferritin...but even ferritin is going in right direction
Are you currently on strictly gluten free diet?
Poor gut function can lead leaky gut (literally holes in gut wall) this can cause food intolerances. Most common by far is gluten. Dairy is second most common.
According to Izabella Wentz the Thyroid Pharmacist approx 5% with Hashimoto's are coeliac, but over 80% find gluten free diet helps, sometimes significantly. Either due to direct gluten intolerance (no test available) or due to leaky gut and gluten causing molecular mimicry (see Amy Myers link)
Changing to a strictly gluten free diet may help reduce symptoms, help gut heal and slowly lower TPO antibodies
While still eating high gluten diet ask GP for coeliac blood test first or buy test online for under £20, just to rule it out first
The predominance of Hashimoto thyroiditis represents an interesting finding, since it has been indirectly confirmed by an Italian study, showing that autoimmune thyroid disease is a risk factor for the evolution towards NCGS in a group of patients with minimal duodenal inflammation. On these bases, an autoimmune stigma in NCGS is strongly supported
In summary, whereas it is not yet clear whether a gluten free diet can prevent autoimmune diseases, it is worth mentioning that HT patients with or without CD benefit from a diet low in gluten as far as the progression and the potential disease complications are concerned
Despite the fact that 5-10% of patients have Celiac disease, in my experience and in the experience of many other physicians, at least 80% + of patients with Hashimoto's who go gluten-free notice a reduction in their symptoms almost immediately.
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Please could someone give advice on blood results 
Updated blood results
Blood test results - anxiety 
