Blood tests are in, what’s going on?? - Thyroid UK

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Blood tests are in, what’s going on??

HashisKate profile image
11 Replies

Hi everyone

My private blood tests have arrived, please can I have some help? Your input would be so appreciated as I am feeling so awful with severe muscle aches etc (see last post)

Here are my results; (I am taking 100mcg Levo & have been for around 8 months)

CRP 0.47 (<5)

TSH (was in the red) 0.181 (0.27 - 4.2)

Free Thyroxine 19 (12-22)

T3 3.82 (3.1 - 6.8)

Thyroglobulin antibodies (red) 436 (<115)

Thyroid proxidase antibodies (red) 65.5 (<34)

Ferritin 75.4 (13-150)

Active b12 64.2 (37.5 - 187.5)

Vitamin d 65.1 (50-175)

I’m so glad I didn’t contact my GP as based on these results and knowing the don’t test T3, they’d probably reduce my Levo!

What can I do next to get well? I don’t currently supplement.

Also does anyone know why my TSH is so low when neither T4 or T3 too high??

Thank you x

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HashisKate
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11 Replies
HashisKate profile image
HashisKate

Also does it mean anything that both sets of antibodies are raised?

SlowDragon profile image
SlowDragonAdministrator

High antibodies confirms autoimmune thyroid disease

Are you currently taking vitamin supplements

Are you on strictly gluten free diet ....if not you need coeliac blood test while still on high gluten diet

Vitamins need some improvement

Vitamin D and B12 are a bit low

Pity there’s no folate result

Poor gut function can lead leaky gut (literally holes in gut wall) this can cause food intolerances. Most common by far is gluten. Dairy is second most common.

According to Izabella Wentz the Thyroid Pharmacist approx 5% with Hashimoto's are coeliac, but over 80% find gluten free diet helps, sometimes significantly. Either due to direct gluten intolerance (no test available) or due to leaky gut and gluten causing molecular mimicry (see Amy Myers link)

Changing to a strictly gluten free diet may help reduce symptoms, help gut heal and slowly lower TPO antibodies

While still eating high gluten diet ask GP for coeliac blood test first or buy test online for under £20, just to rule it out first

healthcheckshop.co.uk/store...?

Assuming test is negative you can immediately go on strictly gluten free diet

(If test is positive you will need to remain on high gluten diet until endoscopy, maximum 6 weeks wait officially)

Trying gluten free diet for 3-6 months. If no noticeable improvement then reintroduce gluten and see if symptoms get worse

chriskresser.com/the-gluten...

amymyersmd.com/2018/04/3-re...

thyroidpharmacist.com/artic...

drknews.com/changing-your-d...

restartmed.com/hashimotos-g...

Non Coeliac Gluten sensitivity (NCGS) and autoimmune disease

ncbi.nlm.nih.gov/pubmed/296...

The predominance of Hashimoto thyroiditis represents an interesting finding, since it has been indirectly confirmed by an Italian study, showing that autoimmune thyroid disease is a risk factor for the evolution towards NCGS in a group of patients with minimal duodenal inflammation. On these bases, an autoimmune stigma in NCGS is strongly supported

ncbi.nlm.nih.gov/pubmed/300...

The obtained results suggest that the gluten-free diet may bring clinical benefits to women with autoimmune thyroid disease

nuclmed.gr/wp/wp-content/up...

In summary, whereas it is not yet clear whether a gluten free diet can prevent autoimmune diseases, it is worth mentioning that HT patients with or without CD benefit from a diet low in gluten as far as the progression and the potential disease complications are concerned

restartmed.com/hashimotos-g...

Despite the fact that 5-10% of patients have Celiac disease, in my experience and in the experience of many other physicians, at least 80% + of patients with Hashimoto's who go gluten-free notice a reduction in their symptoms almost immediately.

Clearly FT3 is very low .....you are likely to need addition of small dose of T3 alongside levothyroxine....but getting vitamins optimal first and trialing strictly gluten free diet first recommended

HashisKate profile image
HashisKate in reply to SlowDragon

Thanks, I’m not coeliac but don’t eat much gluten if any due to ibs and following advice on here.

No I haven’t taken supplements on a regular basis and none in the last 3 months plus

SlowDragon profile image
SlowDragonAdministrator in reply to HashisKate

So first step is to improve vitamins and get coeliac blood test .....Then trial ABSOLUTELY STRICTLY Gluten free diet

Vitamin D

GP will often only prescribe to bring levels to 50nmol.

Some areas will prescribe to bring levels to 75nmol

leedsformulary.nhs.uk/docs/...

GP should advise on self supplementing if over 50nmol, but under 75nmol (but they rarely do)

mm.wirral.nhs.uk/document_u...

NHS Guidelines on dose vitamin D required

ouh.nhs.uk/osteoporosis/use...

But with Hashimoto’s, improving to around 80nmol or 100nmol by self supplementing may be better

ncbi.nlm.nih.gov/pubmed/218...

vitamindsociety.org/pdf/Vit...

Once you Improve level, very likely you will need on going maintenance dose to keep it there.

Test twice yearly via vitamindtest.org.uk

Vitamin D mouth spray by Better You is very effective as it avoids poor gut function. There’s a version made that also contains vitamin K2 Mk7

It’s trial and error what dose we need, with hashimoto’s we frequently need higher dose than average

Calculator for working out dose you may need

40ng/ml = 100nmol

grassrootshealth.net/projec...

Government recommends everyone supplement October to April

gov.uk/government/news/phe-...

Also read up on importance of magnesium and vitamin K2 Mk7 supplements when taking vitamin D

betterbones.com/bone-nutrit...

medicalnewstoday.com/articl...

livescience.com/61866-magne...

sciencedaily.com/releases/2...

Vitamin K2 mk7

betterbones.com/bone-nutrit...

healthline.com/nutrition/vi...

recommended also to supplement a good quality daily vitamin B complex, one with folate in (not folic acid) may be beneficial.

This can help keep all B vitamins in balance and will help improve B12 levels too

chriskresser.com/folate-vs-...

Many Hashimoto’s patients have MTHFR gene variation and can have trouble processing folic acid.

thyroidpharmacist.com/artic...

B vitamins best taken after breakfast

Igennus Super B is good quality and cheap vitamin B complex. Contains folate. Full dose is two tablets per day. Many/most people may only need one tablet per day. Certainly only start on one per day (or even half tablet per day for first couple of weeks)

Or Thorne Basic B or jarrow B-right are other options that contain folate, but both are large capsules

If you are taking vitamin B complex, or any supplements containing biotin, remember to stop these 7 days before any blood tests, as biotin can falsely affect test results

endo.confex.com/endo/2016en...

endocrinenews.endocrine.org...

Low B12 symptoms

b12deficiency.info/signs-an...

Only add one supplement at a time or make one change at a time and wait at least 2 weeks after each change before starting another

HashisKate profile image
HashisKate in reply to SlowDragon

Thanks for replying - I’m not coeliac I’ve had a blood test and an endoscopy.

I will definitely get my levels up for vitamin d using a better you spray. Do you happen to know what an ideal active b12 result would be? Something I should aim for? Should I do the vitamin b supplement alongside a b12 spray?

Thanks again

SlowDragon profile image
SlowDragonAdministrator in reply to HashisKate

I know you aren't coeliac...but extremely common with hashimoto's to be gluten intolerant....so strictly gluten free diet often helps or is essential

Approx 86% hashimoto's patients need to be strictly gluten free

HashisKate profile image
HashisKate in reply to SlowDragon

Yes I agree it’s a shame no folate. I hadn’t realised it was no longer included on the Medichecks

SlowDragon profile image
SlowDragonAdministrator in reply to HashisKate

Taking a good quality daily vitamin B complex will improve all B vitamins, including folate and B12

But remember to stop taking a week before ALL blood tests as B complex contains biotin and biotin can falsely affect test results

Arlie123 profile image
Arlie123 in reply to SlowDragon

I think active b12 needs to be over 100 or total b12 over 550 ideally. Is that right SlowDragon SeasideSusie ?

SeasideSusie profile image
SeasideSusieRemembering in reply to Arlie123

I think active b12 needs to be over 100 or total b12 over 550 ideally.

Active B12 below 70 suggests testing for B12 deficiency according to Viapath at St Thomas' Hospital:

viapath.co.uk/our-tests/act...

Reference range:>70. *Between 25-70 referred for MMA

and for Total B12 the following applies:

According to an extract from the book, "Could it be B12?" by Sally M. Pacholok:

"We believe that the 'normal' serum B12 threshold needs to be raised from 200 pg/ml to at least 450 pg/ml because deficiencies begin to appear in the cerebrospinal fluid below 550".

"For brain and nervous system health and prevention of disease in older adults, serum B12 levels should be maintained near or above 1000 pg/ml."

HashisKate

HashisKate profile image
HashisKate in reply to SeasideSusie

Thank you very much. My active b12 was 65, I had my serum b12 done by the GP last year only to be told it’s fine. I don’t know what the result was but I had a b12 test via Medichecks at the same time and active b12 was 62. So I’m guessing it would have been the low side of normal.

I’ve bought the igennus b that was recommended here so fingers crossed I can get things improved! Will retest in 2-3 months

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