Reacted badly to liothyronine again.: Have... - Thyroid UK

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Reacted badly to liothyronine again.

Mugs19 profile image
4 Replies

Have already received a lot of advice when I reacted badly to what you all considered was too high a dose too soon. After Lyn Mynot's survey of side effects to Teva Levo I examined my prescription and found it was Teva. I have had drug reactions before so decided to change brands and stop the Liothyronine whilst i tested if this eliminated any of the side effects I was getting. After ten days on just Levothyroxine 75 mcg daily I had a big reduction in some of my pain and tried to reintroduce T3 gradually as suggested After2 weeks on 5mcg daily Iwas tolerating it but my symptons of tiredness muscle weakness etc were no better. Raised the dose to 5mcg x 2 daily for 10 days after which I had a huge reaction with extreme pain in my pelvis and back. I have again stopped the T3 and t is slowly alleviating the pain. I have had some blood results taken 1 day after increasing T3 as follows:

CRPHS 0.97 (0-5)

Ferritin 55.2 (13-150)

Vitamins Folate Serum 6,07 (3.89-19.45)

B12 Active 104 (37.5-187.5)

Vit D 71.5 (50-175)

TSH 0.512 (0.27-4.2)

FT3 4.6 (3.1-6.8)

FT4 21.1 (12-22)

TG Antibodies 165 (0-115)

TPO Ab 341 (0-34)

I am on Morningside Liothyronine which does not have Mannitol in it but as I have had adverse reactions before I am pretty sure that is why I feel so bad now. What upsets me is that the very first dose of 20mcg that I took made me feel unrecognisably better for a few hours and seemed to hold out so much promise.I have paid attentions to my diet and eaten no gluten for the past 2 weeks. I was hardly consuming any any way.

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SlowDragon profile image
SlowDragonAdministrator

Personally I think you need to concentrate on improving your vitamins and strictly gluten free diet for longer before trying any T3 .....or certainly trying to increase T3

Exactly what vitamin supplements are you currently taking?

Vitamin D is likely too low

Folate is very low

Ferritin borderline

Optimal vitamin D is at least around 80nmol and frequently we need it around 100nmol

Are you supplementing magnesium?

Mugs19 profile image
Mugs19 in reply to SlowDragon

Thank you for such a prompt reply. Yes , the first thing is to sort out the vitamins. I have just started magnesium and will start the others. I take selenium200 daily and goop (rose hip and vitamin c, turmeric 400 mg x 3 daily. I will attend to my diet and give it time. There is a problem that the Endo may call time on the t3 trial as regulations only allow 3 months. Will cross that bridge if it comes. Thank you again for the advice.

SlowDragon profile image
SlowDragonAdministrator in reply to Mugs19

Vitamin D

GP will only prescribe to bring levels to 50nmol.

ouh.nhs.uk/osteoporosis/use...

But improving to around 80nmol or 100nmol may be better

ncbi.nlm.nih.gov/pubmed/218...

vitamindsociety.org/pdf/Vit...

Once you Improve level, very likely you will need on going maintenance dose to keep it there.

Test twice yearly via vitamindtest.org.uk

Vitamin D mouth spray by Better You is very effective as it avoids poor gut function. There’s a version made that also contains vitamin K2 Mk7

It’s trial and error what dose we need, with hashimoto’s we frequently need higher dose than average

Government recommends everyone supplement October to April

gov.uk/government/news/phe-...

Also read up on importance of magnesium and vitamin K2 Mk7 supplements when taking vitamins

betterbones.com/bone-nutrit...

medicalnewstoday.com/articl...

livescience.com/61866-magne...

sciencedaily.com/releases/2...

Bone pain

easy-immune-health.com/pain...

naturalnews.com/038286_magn...

Vitamin K2 mk7

betterbones.com/bone-nutrit...

folate very low

Supplementing a good quality daily vitamin B complex, one with folate in not folic acid may be beneficial.

chriskresser.com/folate-vs-...

B vitamins best taken in the morning after breakfast

Igennus Super B complex are nice small tablets. Often only need one tablet per day, not two. Certainly only start with one tablet per day after breakfast. Retesting levels in 6-8 weeks

Or Thorne Basic B or jarrow B-right are other options that contain folate, but both are large capsules

If you are taking vitamin B complex, or any supplements containing biotin, remember to stop these 7 days before any blood tests, as biotin can falsely affect test results

endo.confex.com/endo/2016en...

endocrinenews.endocrine.org...

Are you supplementing any B12?

Low vitamin D and low B vitamins may be linked as explained here

drgominak.com/sleep/vitamin...

In YouTube video...vitamin D at 40ng/ml (USA units) is equal to 100nmol (UK units)

Dr Gominak

youtu.be/74F22bjBmqE

Mugs19 profile image
Mugs19 in reply to SlowDragon

Thank you so much for all this information. I will get reading and ordering the right supplements. Best wishes to you.

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