T3 and fluoxetine and trazodone can I take thes... - Thyroid UK

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T3 and fluoxetine and trazodone can I take these together?

789happy profile image
40 Replies

Hello I am new here, and could do with some help. I take 5x25mg T3 and feel so much better but can I take Trazodone or fluoxetine with this T3 as I still struggle with the blues big time. I take 1 vitamin D3 also as blood tests showed that I was low in this. Would be grateful of your thoughts on this

thanks

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789happy
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40 Replies
greygoose profile image
greygoose

You're taking 125 mcg T3 split into 5 doses? You don't really have time to take anything else. How do you manage to eat? Vit D should be taken four hours away from thyroid hormone. And, if you take other things as well, I would imagine that you're not absorbing an awful lot of T3. And, that's possibly why you're on such a high dose. But, can you be more precise about when you take what? Because, ideally, for maximum absorption, you shouldn't take anything at the same time as thyroid hormone. :)

789happy profile image
789happy in reply to greygoose

Hello greygoose I take 5xT3 which are 25mg each in the morning in one go , and one 5000iu vitamin D3 in the evening that's all I take in a day. I am due to do another blood test as I have changed from NTD to t3 over the last month.

greygoose profile image
greygoose in reply to 789happy

OK, I see. Sorry, but what you said before was rather ambiguous! lol So, how much NDT were you taking? Because that is a huge dose of T3. The equivalent of about 6 grains NDT?

789happy profile image
789happy in reply to greygoose

I was taking 5 grains and 2 x 25 mg T3

greygoose profile image
greygoose in reply to 789happy

OK, so that was still quite a hefty dose.

It would appear you don't absorb very well. So, very important to get your ferritin tested, too, as others have said. When are you due your next blood test?

789happy profile image
789happy in reply to greygoose

thought I should do a test in 6 weeks time thinking the T4 from NTD will have left my system by then

greygoose profile image
greygoose in reply to 789happy

It will take about ten weeks to get rid of it completely.

789happy profile image
789happy in reply to greygoose

wow, 10 weeks time then

greygoose profile image
greygoose in reply to 789happy

10 weeks from when you stopped the NDT, that is.

SeasideSusie profile image
SeasideSusieRemembering

You can't take them at the same time as you take your T3, leave as long as possible between them, mimimum 2 hours.

I take 1 vitamin D3 also as blood tests showed that I was low in this

Also, leave plenty of time between D3 and T3. It's 4 hours between Levo and D3 so again I'd leave as long as possible between T3 and D3.

What was your test result for Vit D3? Saying you take 1 x Vit D3 doesn't tell us the dose you are taking and D3 comes in many doses, and the dose you need is crucial and should be based on the result of your test and how to aim for the level recommended by the Vit D Council/Vit D Society (which is 100-150nmol/L or 40-60ng/ml).

Are you also taking D3's very important cofactors - magnesium and Vit Kk2-MK7?

789happy profile image
789happy in reply to SeasideSusie

I did a blood test about 3 months ago, I then started taking two 5,000iu vitamin D3 for the first month and now take just one always in the evening. My blood test then showed my B12 levels to be good. I do take Magnesium baths often but that is all, apart from the 5 T3 in the morning, I feel good and my resting pulse rate is 72

SeasideSusie profile image
SeasideSusieRemembering in reply to 789happy

But what was your test result for Vit D?

It so important to take the right amount because D3 is fat soluble and excess gets stored and can lead to toxicity.

If you were taking 10,000iu daily for a month, that's 300,000iu for the month which is the loading dose for Vit D deficiency of <25nmol/L or <10ng/ml.

Did you retest after the month? It's important to check level after loading dose so that you know what dose to follow up with. 5000iu D3 daily may be too much as a maintenance dose, it's essential to retest now.

Also essential is to take Vit K2-mk7, this is because taking D3 improves uptake of calcium from food and K2 directs calcium to bones and teeth where it is needed and away from arteries and soft tissue where it can be deposited and cause problems such as kidney stones, etc.

789happy profile image
789happy in reply to SeasideSusie

sorry I think I gave your answer to SlowDragon getting a bit confused didn't how much help I would get from everyone thank you

SeasideSusie profile image
SeasideSusieRemembering in reply to 789happy

789happy

Having read all the replies you've posted in the thread, I can't see a result for Vit D anywhere. It will have a unit of measurement of either nmol/L or ng/ml which is important to state when posting the result.

789happy profile image
789happy in reply to SeasideSusie

sorry my vitamin d result was 32 the norm range being 50 - 175

SeasideSusie profile image
SeasideSusieRemembering in reply to 789happy

So 32nmol/L was in the Insufficiency category, not the deficiency category, and you took 10,000iu D3 daily for one month, followed by 5,000iu daily for the following 2 months up to the present time.

If you had been prescribed the loading doses for Vit D deficiency by your GP they would have totalled 300,000iu over 6 weeks then followed by a much lower dose which should be based on the new level after the loading doses.

In the first month you took 300,000iu and the following 2 months you have taken another 300,000iu.

I seriously urge to to retest as a matter of urgency to check your level as you will very likely need to adjust your dose now.

It's also important that you take Vit K2-mk7 as a cofactor of D3. I explained above why it is needed, and it's essential with high dose D3.

789happy profile image
789happy in reply to SeasideSusie

gosh that sounds scary I will stop taking D3 till I get a blood test done and I will sort out Vit k2-mk7 thank you

Marz profile image
Marz

If you are low in VitD then it is possible you will be low in B12 which can also be a cause of LOW mood. How long have you been taking that dose of T3 ?

789happy profile image
789happy in reply to Marz

I have been taking NTD and T3 for about a year I have slowly changed to all T3 . My blood test results were good for B12 but not D

Marz profile image
Marz in reply to 789happy

How good was good ? Over 500 ?

789happy profile image
789happy in reply to Marz

my b 12 results were96.9 with a range of 37.5 - 187.5 as the norm so in the middle of the range

Marz profile image
Marz in reply to 789happy

Ah - the Active test. So yes your result is fine. Are you supplementing ?

789happy profile image
789happy in reply to Marz

no I am not supplementing

SlowDragon profile image
SlowDragonAdministrator in reply to 789happy

Very important to retest vitamin D. Some people only need low dose of vitamin D to improve levels

To much vitamin D is toxic

Have you also tested folate and ferritin

Do you have hashimoto’s? Autoimmune thyroid disease diagnosed by high thyroid antibodies?

789happy profile image
789happy in reply to SlowDragon

yes on 22 November my ferritin was 280 with normal range 13 - 150 . I have since had a blood test on the NHS and my ferritin levels were 280 with a normal range of 50 - 300 I have since given blood. Folate-serum on 22 November was 14.17 with a normal range of 3.89-19.45

I don't know if I have hashimoto's can I get that tested?

SlowDragon profile image
SlowDragonAdministrator in reply to 789happy

Ask GP to test thyroid antibodies

Though You may need to get full Thyroid testing privately as NHS refuses to test TG antibodies if TPO antibodies are negative

Private tests are available. Thousands on here forced to do this as NHS often refuses to test FT3 or BOTH antibodies

thyroiduk.org.uk/tuk/testin...

For thyroid including antibodies and vitamins

Medichecks Thyroid plus ultra vitamin or Blue Horizon Thyroid plus eleven are the most popular choice. DIY finger prick test or option to pay extra for private blood draw. Both companies often have special offers, Medichecks usually have offers on Thursdays, Blue Horizon its more random

If you can get GP to test vitamins and antibodies then cheapest option for just TSH, FT4 and FT3 £29 (via NHS private service )

monitormyhealth.org.uk/thyr...

20% of Hashimoto's patients never have raised antibodies

healthunlocked.com/thyroidu...

789happy profile image
789happy in reply to SlowDragon

I have given up with the GP they just don't want to know and will not do further tests on thyroid. Thank you for your help I have so far used medicheck so will book a test. In july 2019 tsh was 1.89 freeT3 3.9 free Thyroxine 9.39 reverse T3 9.8 and RT3 25.91 I have upped my dose since these results

SlowDragon profile image
SlowDragonAdministrator in reply to 789happy

So you should have thyroid antibodies tested with that Medichecks test in July

Thyroid Peroxidase antibodies and thyroglobulin antibodies

High antibodies confirms cause of hypothyroidism is autoimmune thyroid disease also called hashimoto’s

789happy profile image
789happy in reply to SlowDragon

thyroglobulin antibodies were 12.9

thyroid peroxidase antibodies <9

SlowDragon profile image
SlowDragonAdministrator in reply to 789happy

What’s vitamin D result?

Are you on gluten free diet or tried it?

What’s your most recent TSH, Ft3 and Ft4 result

Recommended on here that all thyroid blood tests should ideally be done as early as possible in morning and before eating or drinking anything other than water .

Last dose of Levothyroxine 24 hours prior to blood test. (taking delayed dose immediately after blood draw).

This gives highest TSH, lowest FT4 and most consistent results. (Patient to patient tip, best not mentioned to GP or phlebotomist)

If/when also on T3, make sure to take last dose 8-12 hours prior to test, even if this means adjusting time or splitting of dose day before test

Is this how you do your tests?

How much T3 are you taking?

How do you take T3 as single or split dose?

Always same brand?

Have you tried adding in small dose of levothyroxine alongside T3

Some of us need good levels of Ft4 and Ft3

789happy profile image
789happy in reply to SlowDragon

my vitamin D was 32 norm levels 50 - 175, no not on any special diets. TSH .005,freeT3 7.84, free Thyroxine 11.6. Yes that is how I take the tests. 150mg T3 in one dose in the morning. Yes doctors put me on levothyroxine for years four a day and I felt awful and exhausted, this is why I started self medicating and now have lots of energy and feel so much better.

789happy profile image
789happy in reply to 789happy

sorry 125mg T3 not 150mg

SlowDragon profile image
SlowDragonAdministrator in reply to 789happy

Vitamin D ideally should be at least 40ng/ml

Windsinger profile image
Windsinger

I am curious that no one answered the original question " T3 and fluoxetine and trazodone can I take these together"? I hope someone will, as I would like to know the answer too... Please 😊

SlowDragon profile image
SlowDragonAdministrator in reply to Windsinger

As they are both antidepressants......it suggests thyroid isn’t correctly treated as depression is frequent hypothyroid symptom

789happy profile image
789happy in reply to SlowDragon

My heart rate is 72 resting and I at last, after years I have energy .The depression has also been a huge problem, which whilst on levothyroxine that caused my severe lack of energy did not help at all, that is why I am taking T3 now , the doctors will not help me . My first question can I take antidepressants with T3 is because I am not in a good place and have to give up the fight and take something.

SlowDragon profile image
SlowDragonAdministrator in reply to 789happy

Many people do take both

Obviously don’t take any other medication at THE SAME TIME as levothyroxine

Levothyroxine must be taken on its own. Any other medication at least 2 hours away

789happy profile image
789happy in reply to SlowDragon

Thank you for that answer

789happy profile image
789happy

yes that would be good to know

Windsinger profile image
Windsinger in reply to 789happy

SlowDragon replied above 😊... I really hope that getting the right dose of T3 would eliminate the need for antidepressants😊

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