Advice please.: Hi i have my latest results could... - Thyroid UK

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Advice please.

Doublevision profile image
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Hi i have my latest results could somebody kindly take a look at them and give me some advice,I do have Hashimotos and i am seeing the Endo soon so would like to go armed with some information.

I am on 75 mg levo which has just been put up 25mg by my GP yesterday.

Free T4 11.4 pmol/l 6.5-17.0

TSH 8.01 ulu/ml 0.34-5.60

Free T3 5.4 pmol/l 4.2-6.7

Vit D 88./nmol/l

Vit b12 276 pg/ml

Serum folate 9.6ng/ml 31-19.9

Serum iron 6.0umol/l 5.0-30.4

Percentage iron saturate 11% 14-51

Serum ferritin 26ng/ml 11-307

I am dairy free i eat a little fish but no meat,i did go gluten free for 6 months but found no difference in how i felt,i am completely exhausted and have brain fog also very emotional.

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SlowDragon profile image
SlowDragonAdministrator

Your thyroid results show you were very under medicated

Bloods should be retested 6-8 weeks after each dose increase

Aim is to bring TSH under 2

Many need TSH under one

Most important results are FT4 and FT3

What’s the ranges on B12 results

Looks very low

Ferritin is far too low, GP should be prescribing iron supplements

SeasideSusie profile image
SeasideSusieRemembering

Doublevision

With these results on 75mcg Levo:

Free T4 11.4 pmol/l 6.5-17.0

TSH 8.01 ulu/ml 0.34-5.60

Free T3 5.4 pmol/l 4.2-6.7

Your GP was right to increase your Levo. Your TSH is way over range and your FT4 is only 47% through it's range.

You should be retested 6-8 weeks after the dose change to check your levels and increase again if necessary.

Vit D 88./nmol/l

This isn't too bad but the Vit D Council recommends a level of 125nmol/L and the Vit D Society recommends a level of 100-150nmol/L. It will down to you to buy your own supplements if you wish to and the Vit D Council suggests supplementing with 2,500iu D3 daily to raise your current level to their recommended level. As you have Hashi's then an oral spray, eg BetterYou, is recommended for best absorption as it bypasses the gut, although some Hashi's patients have done well with an oil based softgel, eg Doctor's Best.

You should retest after 3 months then once the recommended level is reached you'll need to find your maintenance dose by trial and error (it may be 2,000iu D3, maybe more, maybe less, maybe more in winter than summer) and retest twice a year to check levels.

Home fingerprick blood spot test with an NHS lab costs £29 vitamindtest.org.uk/

When taking D3 we also need it's important cofactors - magnesium and Vit K2-MK7 - see vitamindcouncil.org/about-v...

Vit b12 276 pg/ml

This is low. Do you have signs of B12 deficiency? Check here:

b12deficiency.info/signs-an...

If you do you should list them to discuss with your GP and ask for testing for B12 deficiency and pernicious anaemia. Many people with a level in the 300s have been found to need B12 injections.

If you don't have any signs then you could supplement with sublingual methylcobalamin, 1000mcg, use one bottle along with a good B Complex to balance all the B vitamins, then just taking the B Complex should be enough.

According to an extract from the book, "Could it be B12?" by Sally M. Pacholok:

"We believe that the 'normal' serum B12 threshold needs to be raised from 200 pg/ml to at least 450 pg/ml because deficiencies begin to appear in the cerebrospinal fluid below 550".

"For brain and nervous system health and prevention of disease in older adults, serum B12 levels should be maintained near or above 1000 pg/ml."

Serum folate 9.6ng/ml 31-19.9

There appears to be something wrong with that range. Is it 3.1 - 19.9? If so then you're a touch low. Folate is recommended to be at least half way through range so that would be 11.5+

Eating folate rich foods will help, also a good B Compex but don't start taking that until further testing of B12 has been completed, if necessary.

Good B Complex supplements recommended here are Thorne Basic B or Igennus Super B.

Serum iron 6.0umol/l 5.0-30.4

Percentage iron saturate 11% 14-51

Serum ferritin 26ng/ml 11-307

These aren't good. Optimal levels for an iron panel are, according to web.archive.org/web/2018083... :

Serum iron: 55 to 70% of the range, higher end for men - yours is 3.94% through range.

Saturation: optimal is 35 to 45%, higher end for men - yours is 11%

Ferritin: Low level virtually always indicates need for iron supplementation - yours is 5% through the range, recommended is half way through range.

TIBC (total iron binding capacity) or Transferrin: Low in range indicates lack of capacity for additional iron, High in range indicates body's need for supplemental iron - you don't appear to have either of these results

Did you have a full blood count done to include haemoglobin, MCV, MCH, MCHC? These results would show if you have iron deficiency anaemia. If those results are fine then you could have iron deficiency without anaemia. Although they are in range they are very poor and should be discussed with your GP.

Most GPs know little about nutrient levels and where they are best for us, they just see something in range and declare everything is fine, so you may have a problem with getting your B12 and iron looked into. Hashi's often causes low nutrient levels and deficiencies.

If you start any supplements then don't start them all at once. Start with one, give it a week or two and if no adverse reaction then add the next one. Again, wait a week or two and if no adverse reaction add the next one. Continue like this. If you do have any adverse reaction then you will know what caused it.

Vit D, magnesium and iron need to be taken 4 hours away from Levo.

Iron needs to be taken 2 hours away from any other supplements and medication as it affects their absorption.

Doublevision profile image
Doublevision in reply toSeasideSusie

Thankyou so much for your advice Seasidesusie ,i have looked for Mcv,Mch,Mchc but can only find .

Mcv 86.6fl 80.0-99.0

I also have these if they show anything.

Hba1c level(dcct aligned) 6.8 4.5-6.5

Hba1c levl standardised 51mmol/mol 26-48

Gfr calculated abbreviated MDRD 84ml/min N/A

Its no wonder i feel so rubbish i saw an ENT yesterday as i have had horrendous earache for almost 2 years now and he is going to do an MRI on my neck as he thinks the pain may be coming from a thyroid problem!

The message from my GP said i was borderline for my tsh so i needed to raise my levo ,she was right about raising it but borderline!.

I really hope i will be able to sort my health issues out and im grateful for your time.x

SeasideSusie profile image
SeasideSusieRemembering in reply toDoublevision

MCV below range would suggest iron anaemia, so you could have iron deficiency without anaemia. Discuss those iron results with your doctor.

Also discuss your HbA1C results, this looks like a pre-diabetes result.

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