whats the next plan of action ? GP not interest... - Thyroid UK

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whats the next plan of action ? GP not interested in any private blood results.

jenniebee profile image
15 Replies

any suggestions what to do next after recent results .

hi all ,have my medichecks results as recommended by seasidesusie would you have a look and advise what to do next .

vit D 57.5nmol/l (50-175)

vit B12 active 51.2pmol/L (37.5-188)

folate-serum 2.41ug/L >3.89

magnesium serum 0.9mmol/L (0.7-1)

zinc serum 13.36umol/L (10.7-17.5)

ferritin 119ugL (13-150)

CRP hs 12.92mg/L <5

total cholesterol 5.55mmol/L (0-5)

LDL cholesterol 3.19 <3

non HDL cholesterol 4.38mmol/L <4

HDL cholesterol 1.17mmol/L >1.3

total cholesterol:HDL 4.74 ratio <4

tryglycerides 2.61mmol/L <1.7

thankyou

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jenniebee profile image
jenniebee
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15 Replies

Your ferretin looks good but I would want to supplement your vitamin d, folate and B12. I use NOW vit D and K2 spray. I would imagine you have some absorption issues so B12 patches or under the tounge lozenges. I would also suggest you take some vitamin C and zinc to improve your absorption of both nutrician and thyroid hormones as well as bring your zinc up a bit. Do you have white spots on your nails? You GP will only be interested in results out of range and only then if you are lucky re vitamins and minerals. I dont know enough about cholesteral to comment very much other than it appears a bit high which is a symptom of hypothyroidism. The cholesteral test used to be used to diagnose. Optimising thyroid treatment might help.

jenniebee profile image
jenniebee in reply to

hi am currently on 1600iu vit D daily and self medicating 2 grains NDT daily. have more energy than before but as soon as activity stops fatigue takes hold

Nasturtion profile image
Nasturtion in reply to jenniebee

I agree with mandy Jane. Your b12 is definitely low and vitamins d. I havnt read your previous posts but anyone suffering with lack of b12 can feel awfully poorly. I was diagnosed with b12 deficiency. Vit d and folate deficiency . Diagnosed with pernicious anemia so now have b12 injections every 12 weeks. You can get a spray(high dose). B12 from Holland and barrett. It's about £12 a bottle . S have a look at that. And defo vitamins d . Try eating more cereals with added vitamins and folate etc. You can't overdose on b12 as it's just passed out by your urine.its harmless. I have to have injections as my body doesnt make b12. It's not just a deficiency through not enough of the right foods. Go back to your doc and demand to see an endocrinologist. You do have rights.

MaisieGray profile image
MaisieGray in reply to Nasturtion

Just a point - whilst its generally agreed that supplemental vit B12 has a low toxicity in most cases, high levels can't be said to be universally 'harmless'. A 2018 study looked at both very high plasma folate and very high vitamin B12 levels in pregnant women, and found that they were each individually associated with increased risk of autism spectrum disorder in their babies. A 2010 study found that in patients with diabetic kidney disease, high doses of B vitamins (a folic acid, vit B6 & vit B12 combo), compared with placebo, resulted in greater decrease in kidney function and an increase in vascular events, including heart attack and stroke.

helvella profile image
helvellaAdministratorThyroid UK in reply to MaisieGray

I think you mean this paper:

ncbi.nlm.nih.gov/pmc/articl...

A more recent review paper on causes of autism, whilst citing that paper, doesn't even mention B12! Which is interesting but it is not clear why not.

ncbi.nlm.nih.gov/pmc/articl...

And on the kidney disease front, this very recent paper, which cite the 2010,paper, actually comes to the conclusion that folate and B12 supplementation, though possibly not at very high levels (not clear on this) have potential benefit in kidney disease.

ncbi.nlm.nih.gov/pmc/articl...

MaisieGray profile image
MaisieGray in reply to helvella

Yes, am not denying the advantageous nature of supplementation in general, and the paper I referred to cited folate and B12 supplementation as beneficial; but, as I mentioned, it became problematic at very high levels - my point being that it is inaccurate and potentially dangerous to assert that it is absolutely and universally "harmless". Even water isn't harmless in excessive amounts.

experimental1 profile image
experimental1

jenniebee, did you make a typing error of your CRPhs? I hope it was your typo. That test, high sensitivity C-Reactive Protein, a marker of systemic inflammation, looks quite high, unless it was a typo by the lab, a lab calculation error or some other factor(s) that produced that reading. A number that high would have been flagged. I've checked on WebMD and the Mayo Clinic sites to make sure I understand what I'm reading on your results. If that's the actual number,contact Medichecks and ask them for a clarification or request a re-test. My hsCRP, last year, was 2.89 mg/L, putting it at the top of the lab range. Not a good number.

jenniebee profile image
jenniebee in reply to experimental1

hi just looked on last time CRP tested by GP jan 2016 an this is result Serum C reactive protein level 15.0 mg/L [0.0 - 10.0]

experimental1 profile image
experimental1 in reply to jenniebee

Over range, also. It's criminal, IMO, that your doctor won't review your self-ordered labs. Labs are labs, whether ordered by us or a doctor. He or she is an a**hole. The fact that it was elevated three years ago is a red flag, whether of deficiencies, a low grade infection, leaky gut or something else that needs further investigation. Here in the US, the top of the range at the lab I go to is 3.00 and mine was 2.89 mg/L on 10/2019 . I'll be getting retested next month.

HLAB35 has some good recommendations. I could rattle off vitamins and minerals to add to that but, again, there are times it would be good to have a doctor you could work with, as opposed to an arrogant idiot with a stethoscope.

HLAB35 profile image
HLAB35

In her book, The Magnesium Miracle, Dr Carolyn Dean devotes a whole chapter to Cholesterol and Hypertension; there is also a section on C-reactive protein under the chapter on Heart Disease. I recommend you read this book.. as I cannot easily summarise these segments in one paragraph! However, I will quote two extracts,'If sufficient magnesium is present in the body, cholesterol will be limited to it's necessary functions - the production of hormones and the maintenance of membranes - and will not be produced in excess. Remember, most of the cholesterol in the body is produced in the liver, so if it's not needed, the body won't produce it - but this mechanism depends on having sufficient magnesium.' In other words Magnesium acts as a natural statin without all of the side effects. Secondly, CRP is a significant inflammation marker and must be brought down to lower the risk of heart disease, Carolyn Dean says, ' An April 2014 study in the European Journal of Clinical Nutrition concluded, "This meta-analysis and systematic review indicates that dietary Mg intake is significantly and inversely associated with serum CRP levels. The potential beneficial effect of Mg intake on chronic diseases may be, at least in part, explained by inhibiting inflammation." '

Given that you have high cholesterol, high CRP and low vitamin D ( you need Magnesium to help raise vitamin D levels as well) I think it is highly probable that you are Magnesium deficient. Only a RBC blood test ( not available on the NHS, but available through Magnesium aware consultants / functional doctors) will properly show a deficiency. Symptoms are enough, in my opinion, to trial Magnesium in a quality absorbable form - just make sure it is not contra indicated in any medications.

experimental1 profile image
experimental1 in reply to HLAB35

Dr. Dean is sharp and jenniebee's high hsCRP could be a reflection of a deficiency or multiple deficiencies which are driving on inflammation. The fact that her doctor doesn't want to look at her self-ordered labs is problematic. We know most doctors know little about diet and less about supplements. There are times, however, when it's good to have a doctor onboard with whom you can discuss issues and order further tests if needed. That's how I work with my doctors.

HLAB35 profile image
HLAB35 in reply to experimental1

I agree and will do that too and make sure I bring photocopies of any reference material if required... my regular GP is fine with that. It is best to find a few trusted sources of information, ideally by qualified doctors who have done a tonne of research, are known for successfully helping people, and can back up their findings... I keep anything a little more 'out there' to myself and certainly do not mention them to random medical staff. Dr Chaterjee is great ( wish he was my GP) and open-minded even if there is not substantial (pharma approved) evidence. The fact that I am doing better on my low sugar, higher fat/protein, non-celiac, but gluten / casein free diet + a smattering of well-considered supplements is something he and many more GPs these days are ok with and do not consider a fad.

jenniebee profile image
jenniebee in reply to experimental1

hi have read all comments and just ordered Barefoot Nutrition - Vitamin D3 with K2, Magnesium, Boron and Zinc Food Supplement 4000iu - 60 x One a Day Capsules - No artificial fillers or agents and Super B-Complex - High Strength B Vitamins with folate, B6 & B12 plus vitamin C, 60 tablets is there anything i have missed thinking and memory not good at the moment

HLAB35 profile image
HLAB35 in reply to jenniebee

Barefoot nutrition capsules look interesting, but are actually quite low in Magnesium at 100mg, so I would be tempted to add in some extra Magnesium in a few months time if inflammation and cholesterol markers stay stubbornly high.

SlowDragon profile image
SlowDragonAdministrator

Low vitamin D and low B vitamins often go together as explained here

drgominak.com/sleep/vitamin...

Your GP SHOULD prescribe folic acid as your folate is below range

However you may be better off supplementing a good quality daily Vitamin B complex ....

one with folate in not folic acid may be beneficial.

chriskresser.com/folate-vs-...

B vitamins best taken in the morning after breakfast

Recommended brands on here are Igennus Super B complex. (Often only need one tablet per day, not two. Certainly only start with one tablet per day after breakfast. Retesting levels in 6-8 weeks ).

Or Jarrow B-right is popular choice, but is large capsule

If you are taking vitamin B complex, or any supplements containing biotin, remember to stop these 7 days before any blood tests, as biotin can falsely affect test results

endo.confex.com/endo/2016en...

endocrinenews.endocrine.org...

B12 is also low - will improve with a vitamin B complex

Active B12 below 70 is considered suspect

Vitamin D is too low.

GP will only prescribe to bring vitamin D up to 50nmol. Aiming to improve by self supplementing to at least 80nmol and around 100nmol may be better .

Once you Improve level, very likely you will need on going maintenance dose to keep it there.

Retesting twice yearly via vitamindtest.org.uk

Vitamin D mouth spray by Better You is good as avoids poor gut function.

It's trial and error what dose each person needs

Also read up on importance of magnesium and vitamin K2 Mk7 supplements when taking vitamin D

betterbones.com/bone-nutrit...

articles.mercola.com/sites/...

healthy-holistic-living.com...

sciencedaily.com/releases/2...

articles.mercola.com/sites/...

betterbones.com/bone-nutrit...

This article explains should discuss with specialists before taking any vitamin K if you take any blood thinning medication

drsinatra.com/vitamin-k2-su...

Agree with HLAB35 The Magnesium Miracle is well worth reading

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