Advice Please Tyroid and Ferritin

[jamondo]

Okay so been on Levothyroxine for 18 months with result coming down slowly whilst dose being increased. Continued to feel rough, tired, suffering severe depression levels at times, high blood pressure, brain fog.

Read about Hashimoto's Disease and ticked a lot of boxes and discussed this with GP after last TSH levels jumped.

Recent readings :-

19th Sept Non Fasting Test

TSH 3.4mIU/L (0.4 - 5.0)

FT4 12 pmol/L (9-19)

4th October Non Fasting Test _ GP Raised meds to 175m from 150m Levothyroxine

TSH 5.7mIU/L (0.4 - 5.0)

FT4 12 pmol/L (9-19)

31st Oct Fasting Test (No eating or Tyroid meds from 9pm previous evening)

TSH 1.5mIU/L (0.4 - 5.0)

FT4 15 pmol/L (9-19)

Se Tyroid Peroxidase Ab conc TPO Antibody Negative (52 iu/mL)

(Negative <60)

Serum Ferritin 656 ug/L (22.00 - 275ug/L)

Folate 4 ug/L (4.8 - 19ug/L)

Vit B12 539 ng/L (189 - 883 ng/L)

VIT D Level 25-OH its says Test not clinically indicated.

Saw GP who has upped Levotyroxine to 200mg and put me on Folic Acid and doing another blood test next week.

I have quite a clear band around my neck, when I had a scan he said my thyroid was borderline enlarged but on the letter said I was fine. What do you make of my results? Especially the ferritin thats a worry, but strangely I was expecting my TSH to be higher because I fasted.?

[startagaingirl]

Hi - raised ferritin is often due to inflammation somewhere. The body tries to starve the inflammation by withdrawing iron into the ferritin stores instead, hence the raised level. Your GP should be doing another couple of checks to try this down or taking a really good look at your full medical picture to try to tie it down. Have you any gut issues at all? These could be caused by gluten intolerance which would cause inflammation.

You really should have a vit d test as deficiencies can cause a lot of symptoms. If GP won't do it is available through city assays for £28. vitamindtest.org.uk/

Your swinging TSH could be due to Hashis, but the only way to tell really is to have a positive test for either or both of the anti-bodies TpoAb (the one you had tested) and TgAb, which NHS rarely test. As they fluctuate, one negative doesn't prove non Hashis. In your case, since your TpoAb was relatively close to positive, you could perhaps assume positive, or you could try again through either Medichecks or Blue Horizons to test both.

Gillian

[jamondo in reply to startagaingirl]

Thanks Gillian thats really helpful.