Thyroid Antibodies.: Hi Does anyone have any... - Thyroid UK

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Thyroid Antibodies.

lucylocks profile image
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Hi

Does anyone have any information regarding the levels and ranges for thyroid antibodies, and how the levels are interpretated. We all know how Doctors stick rigidly to the TSH range so can we also think they stick to the antibody ranges when diagnosing hashi's.

Both mine are near to top of the range and the TPA have risen

slightly.

May 2017 TPA antibodies 32.02 range 0 - 34, this has risen from 27.5 in August 2015

TPO antibodies 95.77 range 0 - 115.00, same as in August 2015

Even though this is only a small raise in TPA, I did feel very ill around the time of the blood test. I felt I had a really bad virus, shivering and shaking, throbbing whooshing sensation in my head, aches and pains and frequent motions.

My T3 had also dropped low at this time.

I had something very similar to this a couple of months after starting levothyroxine and have had episodes of feeling as though I was getting a virus, but then it did not develop into one, this has happened periodically since diagnoses.

As we know doctors stick rigidly to the ranges but with my antibodies been so high could it actually mean I have hashi's

I have just read a reply to a post from SeasideSusie advising a member she could in fact have hashi's as her TPO are high, but in range.

As anyone got any research papers or info. regarding how the levels and ranges should be interpretated.

Any advice gratefully received.

Thank you,

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lucylocks
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Clutter profile image
Clutter

Lucylocks,

Your May 2017 result 32.02 is for thyoid peroxidase antibodies (TPOab). It is currently negative because it is < 34. As it is rising and close to top of range it is likely you are developing autoimmune thyroiditis (Hashimoto's).

The range 0 - 115 is usually for thyroglobulin antibodies (TgAb). 95.77 is within range so not positive for Hashimoto's.

The symptoms you described could be a Hashi's attack. There is no cure for Hashimoto's which causes 90% of hypothyroidism. Levothyroxine treats the low thyroid levels it causes. Many people have found that 100% gluten-free diet is helpful in reducing Hashi flares, symptoms and eventually antibodies.

chriskresser.com/the-gluten...

thyroiduk.org.uk/tuk/about_...

lucylocks profile image
lucylocks in reply to Clutter

Many thanks clutter,

the different antibodies still confuse me, so I apologise if I have not written them right.

I have had a few attempts of gluten free but always seem to slip up. I really must try harder.

I will have a read of the links you kindly provided, thank you.

Best wishes.

SeasideSusie profile image
SeasideSusieRemembering

Lucy, I think you have that a bit wrong. Whenever my antibodies have been tested this is what they say

Anti-Thyroperoxidase Abs (TPO) <34

Anti-Thyroglobulin Abs (TG) <115

So what are you saying is TPA?

As far as I am aware, if your TPO Abs are greater than 34 this confirms autoimmune thyroid disease. If your TG antibodies are greater than 115, this again confirms autoimmune thyroid disease.

Anything lower doesn't rule it out, it just means the antibodies were low(er) at the time of testing and would be classed as negative. One would need a few negative results to rule out Hashi's.

The post you are referring to, where I mentioned that the antibodies were quite high, was in particular meaning TG Abs.

TgAb 70.170 (0-115)

TPO 15.11 (0-34)

I personally would be keeping an eye on these levels and whether my symptoms fluctuate.

My own antibodies have never been more than 21 for TG and about 13 for TPO, and I've tested 5 or 6 times over the years, about 17 years altogether. As I've never had any fluctuations of symptoms that are common with Hashi's, I have ruled it out.

If your TPO are 32.02 <34 and TG 95.77 <115 then both of yours are close to the top of the range and more than likely suggestive of Hashi's. Some of your symptoms could suggest that too.

lucylocks profile image
lucylocks in reply to SeasideSusie

Many thanks SeasideSusie,

Apologises regarding my mistake in writing the antibodies, they still confuse me as you can see.

Yes I meant the TPO had risen.

I was told by my G.P. when fist diagnosed I did not have hashi's but looking at my high levels made me think I possible could have.

Thank you for explaining things to me.

Best wishes.

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