Thyroid Peroxidase Antibodies

[Zahrazori]

Hello All

Hope your all well and safe

I was wondering if a kind soul can help me again pls this site helped me so much and I feel I need some support again please

I recently went privately and was told my thyroid peroxidase antibodies are very high level 274.0 range is 0-34 iu/ml I was wondering is this something to worry about or is there something I can do to help it come within it’s range I was diagnosed with Graves after a very long period of stress and I was in remission just almost a year now I was hoping someone can help me explain what I can do I’m so worried again x

[greygoose]

You were diagnosed with Grave's, yes, but did you actually have it? Did you every get the results of your TRAB test?

TPO antibodies usually mean Hashi's, and your blood test results two years ago looked far more like Hashi's than Grave's. Do you have any recent TSH/FT4/FT3 results? Are you still taking antithyroid drugs?

[Zahrazori in reply to greygoose]

Thank you for your reply greygoose

I did have Graves and my trab results were high my recent blood test showed all within range spoke to my endocrinologist who said i need to be referred to rheumatologist I definitely had Graves but I am in remission now I have stopped medication for approximately a year now.

[Marz in reply to Zahrazori]

How did the testing for B12 - Folate - Ferritin - VitD gi ? Have been reading your earlier posts and can see testing was suggested.

Can you post your recent results with ranges ?

[Zahrazori in reply to Marz]

Hi Marx all levels are within range

What is gi ?

[Marz in reply to Zahrazori]

Sorry gi a typo !! So what were your in range results? Being in range does not mean optimal ..

[Zahrazori in reply to Marz]

I don’t have the ranges anymore

Do u knw if having this level of tpo is bad

[Marz in reply to Zahrazori]

In my case raised TPO anti-bodies confirmed Hashimotos - back I'm 2005

Do you have your vitamin and mineral results ?

[Zahrazori in reply to Marz]

I don’t have them they checked them a few moths ago and they said they were all fine

[Marz in reply to Zahrazori]

From reading this Forum since 2018 I am sure you will have read daily of the importance of obtaining copies of ALL test results with ranges - results that are legally yours 😷

[Zahrazori in reply to Marz]

I will make sure I get my results thank u for ur help Marz

[ling]

Was your TRAb retested in this latest testing?

Any symptoms currently?

[Zahrazori in reply to ling]

I do have some symptoms like burning hands often and again I need to ask go to retest

[ling in reply to Zahrazori]

You have been off carbimazole for a year? TPO antibodies could indicate either Graves or Hashimoto's. It is likely since u previously had confirmed Graves, the high TPO could be an indication that the Graves will relapse.

I don't think your doctor had your TRAb level tested before stopping the carbimazole? According to the 2018 European Thyroid Association Guideline for the Management of Graves’ Hyperthyroidism, TRAb should be tested to determine if u are suitable to stop carbimazole and try for remission. See here-

karger.com/article/fulltext...

8. Measurement of TSH-R-Ab levels prior to stopping ATD therapy is recommended, as it aids in predicting which patients can be weaned from the medication, with normal levels indicating a greater chance of re￾mission.

9. Patients with persistently high TSH-R-Ab at 12–18 months can continue MMI therapy, repeating the TSH-R-Ab measurement after an additional 12 months, or opt for RAI or thyroidectomy.

Even if your TSH FT4 FT3 levels had been in range but if your TRAb is still above range, you should continue on a low dose of carbimazole. Carbimazole taken long enough, will bring TRAb down to range or zero.

[Zahrazori in reply to ling]

ling I think mine was zero I can recall the test being done

[Zahrazori in reply to ling]

No, I will ask gp to check for me

[Zahrazori]

Hi lora7again

Thank you for sharing your experiences I have read they can lower them somewhere but I wasn’t sure where so I’m trying to find it again

All my levels are done at present and within range

Would u knw if these antibodies can cause miscarriages too?

What has ur consultant said about it?

I’m having a telephone consultation on Friday so I can update more then x

[Zahrazori]

I have lost hope with the NHS too

I lost my identical twins because they failed to pick up I had Graves until 6 moths later they kept saying I had anxiety

Do u knw if there is any help for tpo levels being so high

[Zahrazori]

That’s so sad

The doctors make you so ill similarly the same happened to me they wouldn’t believe me too they said menopause it’s really sad that these doctors can destroy lives too

How are u now ?

Did u have Graves

[Zahrazori]

Where u on a specific diet or did anything different to stay in remission?

I’m really hoping they find a permanent cure for Graves it’s a horrible experience I believe they are doing a research for Graves have you heard about it? Apitope

[Holby18]

I have had extremely high Peroxidase levels for over a decade and have a multi nodular goiter. My GP insists on 6 monthly blood tests which I have had and also kept copies of results. This is must as only you can take control of what is happening.

I have tried a gluten and diary free diet (mostly adhered to it), selenium (or as an alternate three Brazil nuts a day), B12, healthy eating and moderate exercise. It all helps as in ten years my levels have not increased. I am not on medication although this may change as my goiter is getting bigger and eventually I may have to have it removed which means taking thyroxine for the rest of my life.

I have to say that I have never felt unwell in the past decade. I tend not to dwell on negative thoughts as staying positive works wonders. I think suffering from stress is really harmful and I would work on preventing this. Do look after yourself - it will honestly help you. Take care and stay safe.

[Zahrazori in reply to Holby18]

Thank you Holby18 I totally agree how stress can affect u immensely this is what led to my Graves where do u get ur selenium from? How much mg or tablets do u take pls

Thank you for replying means a lot

[littlewelshlamb]

Hi Zahrazori, I've just seen your query regarding miscarriage and I believe TPO can be a cause. I was referred to the Recurrent Miscarriage Clinic after 2 losses (incredibly lucky that my consultant believed in testing every woman after the first 2 losses) I had a whole raft of tests, the only one being high TPO (about 500) He believed this was the cause - as it would mean I have adequate thyroid function normally, but not enough to sustain a pregnacy. I had to start 50mcg Levo before trying to get pregnant, and hey presto, 10 months later I had a healthy baby boy. I've remained on Levo ever since, as my GP said this was safest for me - still wonder if I could have been weaned off it though.

[Zahrazori in reply to littlewelshlamb]

Littlewelsamb

Thank you so much this gives me hope means a lot to me thank you so so much x

[madge1979]

... Zahrazori.. you may be interested to read and learn about

Regular L Carnitine and Acetyl Carnitine

They have been used in the treatment of Graves Disease and there is plenty of Information on the subject .

These two Carnitines have been used to lower the Antibodies in Graves Disease .

Try Googling to find some answers if it is of interest to you .

Good Luck to you ..

Mx🌹

[Zahrazori in reply to madge1979]

Hi Madge

Thank you so much for ur kind reply I will try to look into this

Means a lot thank you all for caring so much xx

[Zahrazori]

Lora7again I’m so sorry to hear you went through such a difficult time similarly this happened to me I lost my dad and he was very poorly I was his only Carer it was very traumatic seeing him so unwell also had to live with a abusive brother who emotionally and physically affected me this all made me so ill that I was in a bad state I really do believe stress can affect u so much pls do stay away from stress and love ur self I try and keep myself happy now