I was diagnosed 11 years ago with hypothyroidism. Been on 100mcg levothyroxine and 20mcg liothyronine throughout prescribed by endocrinologist who I see once a year . Last visit 6 months ago .
I’ve been feeling off for a while and had a private blood test as I have to wait 6 weeks for one with the GP. I am alarmed by my antibody levels ( which have never been tested by NHS so I have no comparison )
Thyroglobulin antibodies range 0-115
Mine are 1073kIU/L
Thyroid peroxidase Antibodies range 0-34
Mine are 492 kIU/L
Cortisol is also low . Range 133-537.
Mine is 124 nmol/L
TSH is 0.006 . It has been suppressed for years . Free T3 5.9 and Free Thyroxine 17.5
All other markers and vitamins are in range
I scanned the results to the Endo . He stated the antibodies were not a concern as they are not clinically relevant . Reduced my Levo to 75mcg and is arranging a sycanthen test to check my adrenal glands . “Dr google “says high antibodies can indicate thyroid cancer
Should I be concerned and insist on a thyroid scan ( I’ve never had one )
thank you in advance
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brewster01
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Recommended that all thyroid blood tests early morning, ideally just before 9am, only drink water between waking and test and last dose levothyroxine 24 hours before test
This gives highest TSH, lowest FT4 and most consistent results. (Patient to patient tip)
T3 ….day before test split T3 as 2 or 3 smaller doses spread through the day, with last dose approximately 8-12 hours before test
Is this how you do your tests?
About 90% of primary hypothyroidism is autoimmune thyroid disease, usually diagnosed by high TPO and/or high TG thyroid antibodies
Autoimmune thyroid disease with goitre is Hashimoto’s
Autoimmune thyroid disease without goitre is Ord’s thyroiditis.
Both are autoimmune and generally called Hashimoto’s.
In U.K. medics hardly ever refer to autoimmune thyroid disease as Hashimoto’s (or Ord’s thyroiditis)
Hashimoto's affects the gut and leads to low stomach acid and then low vitamin levels
Low vitamin levels affect Thyroid hormone working
when were vitamin D, folate, B12 and ferritin last tested
Thorne Basic B recommended vitamin B complex that contains folate, but they are large capsules. (You can tip powder out if can’t swallow capsule) Thorne can be difficult to find at reasonable price, should be around £20-£25. iherb.com often have in stock. Or try ebay
IMPORTANT......If you are taking vitamin B complex, or any supplements containing biotin, remember to stop these 7 days before ALL BLOOD TESTS , as biotin can falsely affect test results
In week before blood test, when you stop vitamin B complex, you might want to consider taking a separate folate supplement (eg Jarrow methyl folate 400mcg) and continue separate B12
Post discussing how biotin can affect test results
once your serum B12 is over 500 (or Active B12 level has reached 70), you may be able to reduce then stop the B12 and just carry on with the B Complex.
If Vegetarian or vegan likely to need ongoing separate B12 few times a week
My B12 active was 126 and I had stopped taking it 2 weeks before the test so I have not resumed as it is in range without the supplement . What are your thoughts on the alarmingly high antibody results ?
Poor gut function can lead leaky gut (literally holes in gut wall) this can cause food intolerances.
Most common by far is gluten.
Dairy is second most common.
A trial of strictly gluten free diet is always worth doing
Only 5% of Hashimoto’s patients test positive for coeliac but a further 81% of Hashimoto’s patients who try gluten free diet find noticeable or significant improvement or find it’s essential
A strictly gluten free diet helps or is essential due to gluten intolerance (no test available) or due to leaky gut and gluten causing molecular mimicry (see Amy Myers link)
Changing to a strictly gluten free diet may help reduce symptoms, help gut heal and may slowly lower TPO antibodies
While still eating high gluten diet ask GP or endocrinologist for coeliac blood test first as per NICE Guidelines
The predominance of Hashimoto thyroiditis represents an interesting finding, since it has been indirectly confirmed by an Italian study, showing that autoimmune thyroid disease is a risk factor for the evolution towards NCGS in a group of patients with minimal duodenal inflammation. On these bases, an autoimmune stigma in NCGS is strongly supported
In summary, whereas it is not yet clear whether a gluten free diet can prevent autoimmune diseases, it is worth mentioning that HT patients with or without CD benefit from a diet low in gluten as far as the progression and the potential disease complications are concerned
Despite the fact that 5-10% of patients have Celiac disease, in my experience and in the experience of many other physicians, at least 80% + of patients with Hashimoto's who go gluten-free notice a reduction in their symptoms almost immediately.
Similarly few months later consider trying dairy free too. Approx 50-60% find dairy free beneficial
With loads of vegan dairy alternatives these days it’s not as difficult as in the past
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High thyroid antibodies
Thyroid function is fine thyroid antibodies very high. What's going on?
Vitamin D deficiency and very high thyroid peroxidase antibody test result
Is it possible to have high thyroid antibodies without having hashimotos? 
