As shown from my saliva cortisol test, I have very high cortisol level especially in the morning and depressed DHEA, I read somewhere that high cortisol interferes in the transfer from T4 to T3 so can you advise on this issue? Also high cortisol and low DHEA affects the testosterone level which was low in my case. The question I need to ask is why I might have high cortisol is it because the T4 is not converting to T3 and rather to RT3 which is high in my case? Also, I have low vitamin D, low folate, somehow low B12, I might have low stomach acid and bad absorption of vitamins and minerals . Main Symptoms are low temperature and total hair loss. Does the sympathetic nervous system play a role in all this? I am on T4 medicine for 17 years and doctors refuse to consider changing the medicine?