I found a post about this but since it's a couple of years old I thought it would be preferable to start a new thread.
I have read that Thyroid-S contains a substance that will cause it to pass through the stomach and not be absorbed until it has reached the intestine. This will supposedly result in slower release of hormones into the bloodstream and more stable hormone levels. If you chew it up before swallowing, will that not cause the pill to melt and be digested in the stomach already? Those of you who chew Thyroid-S up, have you noticed a difference in how it effects you compared to when you swallow the pills?
I like Thyroid-S more and more, as I feel stable on it (on other brands of NDT, I have tended to feel ups and downs, probably because I take it once a day for the sake of convenience instead of multi dosing). I have no hypo symptoms left that I can think of, and I am not gaining weight (usually the first sign I am under medicated). But my FTs are lowish considering the dose I take; this summer, on 7 grains of Thyroid-S, my FT4 levels were at the bottom of range and my FT3 levels midrange only, 24 h after latest dose. I feel fine, so I am not really worried; I am just wondering if anyone has gone from swallowing to chewing Thyroid-S up, and noticed a difference in symptoms or lab results...?
This question only concerns Thyroid-S, as it's the only brand of NDT (to my knowledge) to contain a slow-release substance (I think it's called Eudragit).