Thyroid UK
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Increase in NDT and blood show no improvement

I have been advised by my new Endo to raise my NDT from 2 grains to 3 grains. And I have had bloods done and my Free T4 and T3 have not improved, but my TSH has gone right down, he did folate, ferritin and B12 again has anyone got any ideas please?

Results and ranges

Free T4 11.8 (12.0-22.0)

Free T3 5.4 (3.1-6.8)

TSH 0.10 (0.27-4.20). Was 1.89

Vitamin B12. 343 (190-660)

Folate 5.8 (5.0-10.0)

Ferritin 74 (13--150)

My Endo would like my FT4 higher and has recommended another 1/2 grain increase

I take two ferritin tablets a day.

5 Replies

How long ago did you increase from 2 to 3 grains?

You really need to get the B12 and folate up. I would recommend 5000 mcg sublingual methylcobalaming daily. Plus a B complex with methylfolate, rather than folic acid to bring the folate up.

1 like

Hi Greygoose, I started the increase 6 weeks ago, the blood test I had done last week show lower levels than when I was on 2 grains last year


Well, jumping a whole grain is a big increase in one go. So, maybe it will take longer for the blood tests to catch up.

However, I Don't think you're going to get that FT4 any higher, because the body just doesn't hang on to it when you're taking T3 as well. Because it just doesn't need it anymore. Your endo ought to know that!


O did the increase at 1/2 tablet for two weeks then upped it to 1 after that, been on 3 now for a month


OK, well, I still say that you are not going to get that FT4 any higher. It's low because you're taking T3.

But, if you still have symptoms, then there is room for an increase to get your FT3 a bit higher. But that will lower your TSH even more. Don't know how your endo will like that! lol


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