So I made the switch to NDT just this past week. My doc prescribed Erfa thyroid one 30 mg tab twice a day (so total 60 mg). so I take one at 7:00 am and the other at 2:00 pm. This is now day 4 and I am more achey, more emotional, gut upset, and generally tired (tho not as exhausted in late afternoon and into the evening).
Prior to starting the erfa NDT, I was taking .125 synthroid and 5mcg slow release cytomel each morning and 1/2 capsule of over the counter 65mg thyroid at 1:00 in the afternoon. Initially felt better with the addition of the 1/2 capsule but, after three weeks or so, had noticed higher fatigue and constipation returning.
My labs done just prior to starting the Erfa NDT were:
TSH : .03
Free T4: 23.5 (range 10 to 25)
FreeT3: 3.8. (Range 3.6 to 6.8)
TPO: 113. (Up from 85 at previous measurement before over the counter NDT)
So my doc is telling me the NDT dose I am on contains less T4 and more T3 so she is hoping to see the T4 go down (goal is around 18) and the T3 to go up (goal is around 5).
In the meantime I am not feeling great. I tend to be very sensitive to changes in dose of almost anything.
Is it usual for people to have difficulty with this transition? Does the dosage and the rationale for the dose i am now on make sense?
Any suggestions or thoughts would be much appreciated!!