Thyroid UK

Metabolic disorders and nutritional status in autoimmune thyroid diseases

An interesting paper which pulls together several thoughts/ideas about thyroid and diet with a lot of focus on vitamins, coeliac disease and gluten/gliadin, protein and sugars. Quite a lof of confirmation of what has often been posted here.

Metabolic disorders and nutritional status in autoimmune thyroid diseases

Zaburzenia metaboliczne i stan odżywienia w autoimmunologicznych chorobach tarczycy

Anna Kawicka, Bożena Regulska-Ilow

Department of Dietetics, Wroclaw Medical University, Wroclaw, Poland


In recent years, the authors of epidemiological studies have documented that autoimmune diseases are a major problem of modern society and are classified as diseases of civilization. Autoimmune thyroid diseases (ATDs) are caused by an abnormal immune response to autoantigens present in the thyroid gland – they often coexist with other autoimmune diseases. The most common dysfunctions of the thyroid gland are hypothyroidism, Graves-Basedow disease and Hashimoto’s disease. Hashimoto’s thyroiditis can be the main cause of primary hypothyroidism of the thyroid gland.

Anthropometric, biochemical and physicochemical parameters are used to assess the nutritional status during the diagnosis and treatment of thyroid diseases. Patients with hypothyroidism are often obese, whereas patients with hyperthyroidism are often afflicted with rapid weight loss. The consequence of obesity is a change of the thyroid hormones’ activity; however, weight reduction leads to their normalization. The activity and metabolic rate of thyroid hormones are modifiable.

ATDs are associated with abnormalities of glucose metabolism and thus increased risk of developing diabetes mellitus type 1 and type 2. Celiac disease (CD) also increases the risk of developing other autoimmune diseases.

Malnutrition or the presence of numerous nutritional deficiencies in a patient’s body can be the cause of thyroid disorders. Coexisting deficiencies of such elements as iodine, iron, selenium and zinc may impair the function of the thyroid gland. Other nutrient deficiencies usually observed in patients suffering from ATD are: protein deficiencies, vitamin deficiencies (A, C, B6, B5, B1) and mineral deficiencies (phosphorus, magnesium, potassium, sodium, chromium). Proper diet helps to reduce the symptoms of the disease, maintains a healthy weight and prevents the occurrence of malnutrition. This article presents an overview of selected documented studies and scientific reports on the relationship of metabolic disorders and nutritional status with the occurrence of ATD.

autoimmune thyroid disease • metabolic disorders • nutritional deficiencies • nutritional status

Link to full paper as PDF:

PubMed link:


3 Replies

Thanks Rod - think this is something many of us talk about with grim regularity :-) Healthy guts...

Thank you for posting....


Really interesting article, thank you. I am convinced this is key to all good health.


I am learning more and more how important the gut is. I bet that there are millions of people out there that have hypo/hyper problems that are not even aware of all this. It is because I have studied and studied and used these wonderful sites to learn. I know myself that I am finding I am low in most vits ex- ferritin, vit d, b12 etc. No endocronologist ever asks this why oh why have we been left in the dark for son long. No wonder that it has become a world wide epedemic.


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