NDT question about dosage: Hello, Does anyone... - Thyroid UK

Thyroid UK

140,948 members166,084 posts

NDT question about dosage

Jemari profile image
9 Replies

Hello,

Does anyone know where I can get some good advice/information about taking NDT after coming off synthetic thyroxine please?

I have been taking synthetic T4 + T3 for the last ten years, having been diagnosed with Hashimoto's fifteen years ago. T4 alone didn't work well for me, the dose kept rising, but I still felt awful.

I was also taking Omeprazole (I have acid reflux and other digestive issues, including constipation) for as long, but gave this up last year, because I am now not absorbing nutrients properly. I had a course of 6 x B12 injections two months ago and am taking vitamin D, calcium, magnesium, enzymes and probiotics.

Two weeks ago, I started on NDT, 1/2 grain Nature-throid (on private prescription from my GP after I asked for it) but I don't have any instructions about taking it. The pharmacist couldn't help. I'm feeling marginally better, although tired (nothing new :-) so I wonder if I should just stay on this dose until my next blood test, which I expect will be next month when I see my GP?

I was on 100 mcg T4 and 20 mcg T3. I've had a look on the internet, so I know my current dose is low compared to that.

Thank you for reading this. :-)

Written by
Jemari profile image
Jemari
To view profiles and participate in discussions please or .
Read more about...
9 Replies
helvella profile image
helvellaAdministrator

We often see the suggestion that one grain of any of the prescription desiccated thyroid products works out to be similar to 75 micrograms of levothyroxine. The manufacturers usually suggest one grain as about 100 micrograms of levothyroxine but I think that is conservative.

getrealthyroid.com/the-real...

(Despite the corny site name, that really is the makers of Nature-Throid.)

Your 100 T4 + 20 T3 (using one "conversion" factor) could work out at 160 micrograms of levothyroxine.

Your half grain of Nature-Throid could work out at 37.5 micrograms of levothyroxine.

Which is something like one quarter of the dose you were on! That isn't just a bit low, it is a gross under-dose.

The chart I linked to suggests about 1.5 grains. I suggest that your doctor and pharmacist don't know what they are doing and can't read.

Rod

Jemari profile image
Jemari in reply tohelvella

Thank you for your help, Rod.

I think, after reading one of the links below, they may have started me on a minimal dose because some people get adverse reactions (I'm a bit prone to those, unfortunately). It would have been really helpful if they could have told me that, though. :-) It seems I should increase by 1/2 grain after the first week (oops, missed that) for three more weeks, and then increase again, until I reach my optimal dose. I'll start that today.

helvella profile image
helvellaAdministrator in reply toJemari

Do bear in mind that you were already taking some T3 so super-caution with respect to that constituent seems unnecessary.

It is all very well being cautious, but under-dosing has its own set of problems. For example, there are people who get palpitations from being under-dosed. I'd put it down to ignorance rather than caution, sadly.

Rod

shaws profile image
shawsAdministrator

This is quite a useful site:-

stopthethyroidmadness.com/t...

stopthethyroidmadness.com/m...

Jemari profile image
Jemari in reply toshaws

Thank you, that's a very useful chart. I stopped looking at STTM when they started to scaremonger about some research correlations, but there is obviously some interesting and valuable information on there. I appreciate you taking the time to send me the link. :-)

humanbean profile image
humanbean

tpauk.com/forum/content.php...

Part way down the page is a section entitled : How to Dose with Natural Desiccated Porcine Thyroid Extract

But read the whole page anyway.

Jemari profile image
Jemari in reply tohumanbean

Wow, this is perfect, thank you. It explains my low starting dose too. Very much appreciated. :-)

humanbean profile image
humanbean in reply toJemari

The link I gave is outdated - the new one is :

tpauk.com/forum/resources/t...

cheljane2 profile image
cheljane2

Hello if you go to the website for nature throid by rlc labs they have a conversion chart of all thyroid medication.this will tell u if on 100 levo equivelent nature throid is 1 grain and so on with armour etc.i used it when i changed over.and if i remember liothyronine 5 is equivelent to 25 levo.

Not what you're looking for?

You may also like...

Switched over to NP Thyroid from Synthroid

My GP has finally agreed to switch me to NDT. I have been taking Synthroid for 16 years. But only...
clairclaire profile image

NDT sublingually.

Hello. Male, 40 years old. I want to share my results after trying NDT sublingually to see if this...
Lucas22 profile image

Becoming resistant to NDT dosage?

I posted this question initially over on the Ray peat forum, but I'm cross posting it here to see...

Synthroid and NDT

Hello everyone I have taken NDT for over 7 years and I never felt well no matter what dose I was on...
dragonfly76 profile image

Immediate improvement when switching from NDT to synthetic combo?

I have not been feeling so great on NDT lately and, after reading about other people feeling better...

Moderation team

See all
PurpleNails profile image
PurpleNailsAdministrator
helvella profile image
helvellaAdministrator
SlowDragon profile image
SlowDragonAdministrator

Content on HealthUnlocked does not replace the relationship between you and doctors or other healthcare professionals nor the advice you receive from them.

Never delay seeking advice or dialling emergency services because of something that you have read on HealthUnlocked.